The Expression of the Epithelial Blood-group Substances: Normal and Malignant Tissues

The blood-group isoantigens are macromolecules localized to the plasma membranes of certain epithelial tissues.2,11-15 These substances are not detectable on the epithelium once it has undergone malignant transformation.2,9,13 Results of this investigation have demonstrated that the loss of detectability of the blood-group isoantigens does not appear to be related to a "masking" effect by an increase in surface sialic acid. Using fluorescein-labeled lectins specific for sugar subunits which are components of the blood-group oligosaccharide chain, it was found that the malignant cells and cells of the para basal layer of normal oral epithelium had high levels of N-acetyl-D-glucosamine (GlcNAC), the subterminal sugar residue of the blood-group chain. The basal cells of normal epithelium and a minority of the malignant cells demonstrated levels of D-galactose-N-acetyl-D-galactosamine, which are the most proximal blood-group sugar subunits, as well as subunits of other membrane antigens. Our results indicate that malignant cells seem to be capable of synthesizing the blood-group oligosaccharide chains to the same level as the normal cells of the para basal layer of stratified squamous epithelium. This level is just subjacent to the terminal D-galactose residue of the blood-group precursor chain. Increased or decreased differentiation characteristics of squamous cell carcinomas did not alter the level of blood-group synthesis. However, there may be a correlation between the level of synthesis of these antigens and the ability of the cells to demonstrate motility and to proliferate.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/66719/2/10.1177_00220345800590112001.pd

Cell Proliferation after Flap Surgery, Root Conditioning and Fibronectin Application

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141171/1/jper0661.pd

Hall Effect in a Quasi-One-Dimensional System

We consider the Hall effect in a system of weakly coupled one-dimensional chains with Luttinger interaction within each chain. We construct a perturbation theory in the inter-chain hopping term and find that there is a power law dependence of the Hall conductivity on the magnetic field with an exponent depending on the interaction constant. We show that this perturbation theory becomes valid if the magnetic field is sufficiently large.Comment: 20 page

Oxygen-conducting Composites Based on Me2(WO4)3 (Me = Sm, Al)

Composites Sm2(WO4)3-WO3 and Al2(WO4)3-WO3 were prepared by the solid-state method and a systematic study of their electrotransport properties has been carried out. A sharp increase in the oxygen-ion conductivity is observed in composites Sm2(WO4)3–WO3 at small WO3 values (about 10 mol.%). This effect is probably caused by formation of the non-autonomous interface phase covering grain boundaries of Sm2(WO4)3. These composite O2− – electrolytes are perspective materials for high temperature fuel cells. Тhe composite effect is absent in the Al2(WO4)3–WO3 system. This is probably due to the negative thermal expansion coefficient of Al2(WO4)3, which prevents the formation of a continuous high-conducting microphase film. Keywords: composites, ionic conductivity, heterogeneous doping, microphas

Hall effect in quasi one-dimensional organic conductors

We study the Hall effect in a system of weakly coupled Luttinger Liquid chains, using a Memory function approach to compute the Hall constant in the presence of umklapp scattering along the chains. In this approximation, the Hall constant decomposes into two terms: a high-frequency term and a Memory function term. For the case of zero umklapp scattering, where the Memory function vanishes, the Hall constant is simply the band value, in agreement with former results in a similar model with no dissipation along the chains. With umklapp scattering along the chains, we find a power-law temperature dependance of the Hall constant. We discuss the applications to quasi 1D organic conductors at high temperatures.Comment: Proceedings of the ISCOM conference "Sixth International Symposium on Crystalline Organic Metals, Superconductors, and Ferromagnets", Key West, Florida, USA (Sept. 2005), to be plublished in the Journal of Low Temperature Physic

The Role of Structured Telephone Support in the Development of Self-care in Comorbid Patients with Chronic Heart Failure

Aim. To research the effect of structured telephone support on the self-care in comorbid patients with chronic heart failure (CHF) over 12 months of follow-up.Material and methods. Self-care was assessed using The Self-care of Heart Failure Index (SCHFI, version 6.2) in 130 patients with CHF II-IV functional class according to NYHA, mean age 63.2±9.6 years old, left ventricular ejection fraction averaged 47.1±11.6%, men (70.8%) and patients with ischemic etiology of CHF (78.5%) prevailed. After fixed simple randomization by the envelope method, the patients were divided into groups of standard (control) and active outpatient follow-up (additional telephone contacts or correspondence using available messengers – structured telephone support). All patients received CHF therapy in accordance with the current Russian clinical guidelines. The indicators evaluated initially and after 12 months of follow-up.Results. Over 12 months, total SCHFI scores increased significantly by 62% in the telephone support group and by 34.7% in the comparison group (p<0.001). A significant maximum improvement in the score was noted in section B of this scale (self-care management) in patients in the telephone support group (by 100%; p<0.001).There was an improvement in the clinical condition and an increase in exercise tolerance in both groups, somewhat more in the telephone support group (p>0.05).However, there were no statistically significant differences in the intake of the main groups of drugs and the achievement of their target dosages (p>0.05).Conclusion. The study found a positive effect of structured telephone support on the self-care and the clinical condition of patients with CHF, although it did not reach the maximum possible acceptable values. Further studies are need to assess the self-care in patients with CHF

Instanton approach to the Langevin motion of a particle in a random potential

We develop an instanton approach to the non-equilibrium dynamics in one-dimensional random environments. The long time behavior is controlled by rare fluctuations of the disorder potential and, accordingly, by the tail of the distribution function for the time a particle needs to propagate along the system (the delay time). The proposed method allows us to find the tail of the delay time distribution function and delay time moments, providing thus an exact description of the long-time dynamics. We analyze arbitrary environments covering different types of glassy dynamics: dynamics in a short-range random field, creep, and Sinai's motion.Comment: 4 pages, 1 figur

Effect of Citric Acid and Various Concentrations of Fibronectin on Healing Following Periodontal Flap Surgery in Dogs

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/142283/1/jper0667.pd

On Lagrangian formulations for arbitrary bosonic HS fields on Minkowski backgrounds

We review the details of unconstrained Lagrangian formulations for Bose particles propagated on an arbitrary dimensional flat space-time and described by the unitary irreducible integer higher-spin representations of the Poincare group subject to Young tableaux $Y(s_1,...,s_k)$ with $k$ rows. The procedure is based on the construction of Verma modules and finding auxiliary oscillator realizations for the symplectic $sp(2k)$ algebra which encodes the second-class operator constraints subsystem in the HS symmetry algebra. Application of an universal BRST approach reproduces gauge-invariant Lagrangians with reducible gauge symmetries describing the free dynamics of both massless and massive bosonic fields of any spin with appropriate number of auxiliary fields.Comment: 8 pages, no figures, extended Contribution to the Proceedings of the International Workshop "Supersymmetry and Quantum Symmetries" (SQS'2011, July 18- July 23, 2011, Dubna, Russia), v.2: 9 pages, 2 references with comments in Introduction adde

MAIN STAGES OF CONTINENTAL CRUST FORMATION IN THE WESTERN ALDAN SHIELD: CONSTRAINTS FROM SM-ND ISOTOPE SYSTEMATICS OF CENOZOIC SANDS IN THE CHARA AND TOKKA BASINS

Previous geochronological and Sm-Nd isotopegeochemical studies have identified the main stages of the Precambrian continental crust formation in the central and eastern parts of the Aldan Shield [Kotov et al., 2006], while its western part (Chara-Olekma Geoblock) has not been adequately investigated yet in this respect.Previous geochronological and Sm-Nd isotopegeochemical studies have identified the main stages of the Precambrian continental crust formation in the central and eastern parts of the Aldan Shield [Kotov et al., 2006], while its western part (Chara-Olekma Geoblock) has not been adequately investigated yet in this respect