1,017 research outputs found

    Complexity science for sleep stage classification from EEG

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    Automatic sleep stage classification is an important paradigm in computational intelligence and promises consider- able advantages to the health care. Most current automated methods require the multiple electroencephalogram (EEG) chan- nels and typically cannot distinguish the S1 sleep stage from EEG. The aim of this study is to revisit automatic sleep stage classification from EEGs using complexity science methods. The proposed method applies fuzzy entropy and permutation entropy as kernels of multi-scale entropy analysis. To account for sleep transition, the preceding and following 30 seconds of epoch data were used for analysis as well as the current epoch. Combining the entropy and spectral edge frequency features extracted from one EEG channel, a multi-class support vector machine (SVM) was able to classify 93.8% of 5 sleep stages for the SleepEDF database [expanded], with the sensitivity of S1 stage was 49.1%. Also, the Kappa’s coefficient yielded 0.90, which indicates almost perfect agreement

    1.3 mm Polarized emission in the circumstellar disk of a massive protostar

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    We present the first resolved observations of the 1.3 mm polarized emission from the disk-like structure surrounding the high-mass protostar Cepheus A HW2. These CARMA data partially resolve the dust polarization, suggesting a uniform morphology of polarization vectors with an average position angle of 57° ± 6° and an average polarization fraction of 2.0% ± 0.4%. The distribution of the polarization vectors can be attributed to (1) the direct emission of magnetically aligned grains of dust by a uniform magnetic field, or (2) the pattern produced by the scattering of an inclined disk. We show that both models can explain the observations, and perhaps a combination of the two mechanisms produces the polarized emission. A third model including a toroidal magnetic field does not match the observations. Assuming scattering is the polarization mechanism, these observations suggest that during the first few 104 years of high-mass star formation, grain sizes can grow from1 mm to several 10s μm.Fil: Fernandez Lopez, Manuel. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Instituto Argentino de Radioastronomía. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Argentino de Radioastronomia; ArgentinaFil: Stephens, I. W.. Harvard-Smithsonian Center for Astrophysics; Estados Unidos. Boston University; Estados Unidos. University of Illinois; Estados UnidosFil: Girart, J. M.. Harvard-Smithsonian Center for Astrophysics; Estados Unidos. Institut de Ciències de l’Espai; EspañaFil: Looney, L.. University of Illinois; Estados UnidosFil: Curiel, S.. Universidad Nacional Autónoma de México; MéxicoFil: Segura Cox, D.. University of Illinois; Estados UnidosFil: Eswaraiah, C.. National Tsing Hua University; República de ChinaFil: Lai, S. P.. National Tsing Hua University; República de Chin

    Radioactive Probes of the Supernova-Contaminated Solar Nebula: Evidence that the Sun was Born in a Cluster

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    We construct a simple model for radioisotopic enrichment of the protosolar nebula by injection from a nearby supernova, based on the inverse square law for ejecta dispersion. We find that the presolar radioisotopes abundances (i.e., in solar masses) demand a nearby supernova: its distance can be no larger than 66 times the size of the protosolar nebula, at a 90% confidence level, assuming 1 solar mass of protosolar material. The relevant size of the nebula depends on its state of evolution at the time of radioactivity injection. In one scenario, a collection of low-mass stars, including our sun, formed in a group or cluster with an intermediate- to high-mass star that ended its life as a supernova while our sun was still a protostar, a starless core, or perhaps a diffuse cloud. Using recent observations of protostars to estimate the size of the protosolar nebula constrains the distance of the supernova at 0.02 to 1.6 pc. The supernova distance limit is consistent with the scales of low-mass stars formation around one or more massive stars, but it is closer than expected were the sun formed in an isolated, solitary state. Consequently, if any presolar radioactivities originated via supernova injection, we must conclude that our sun was a member of such a group or cluster that has since dispersed, and thus that solar system formation should be understood in this context. In addition, we show that the timescale from explosion to the creation of small bodies was on the order of 1.8 Myr (formal 90% confidence range of 0 to 2.2 Myr), and thus the temporal choreography from supernova ejecta to meteorites is important. Finally, we can not distinguish between progenitor masses from 15 to 25 solar masses in the nucleosynthesis models; however, the 20 solar mass model is somewhat preferred.Comment: ApJ accepted, 19 pages, 3 figure

    Modeling the magnetic field in the protostellar source NGC 1333 IRAS 4A

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    Magnetic fields are believed to play a crucial role in the process of star formation. We compare high-angular resolution observations of the submillimeter polarized emission of NGC 1333 IRAS 4A, tracing the magnetic field around a low-mass protostar, with models of the collapse of magnetized molecular cloud cores. Assuming a uniform dust alignment efficiency, we computed the Stokes parameters and synthetic polarization maps from the model density and magnetic field distribution by integrations along the line-of-sight and convolution with the interferometric response. The synthetic maps are in good agreement with the data. The best-fitting models were obtained for a protostellar mass of 0.8 solar masses, of age 9e4 yr, formed in a cloud with an initial mass-to-flux ratio ~2 times the critical value. The magnetic field morphology in NGC 1333 IRAS 4A is consistent with the standard theoretical scenario for the formation of solar-type stars, where well-ordered, large-scale, rather than turbulent, magnetic fields control the evolution and collapse of the molecular cloud cores from which stars form.Comment: 4 pages, 5 figures. Accepted by Astronomy and Astrophysic

    The immediate environment of the Class 0 protostar VLA1623, on scales of ~50-100 AU, observed at millimetre and centimetre wavelengths

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    We present high angular resolution observations, taken with the Very Large Array (VLA) and Multiple Element Radio Linked Interferometer Network (MERLIN) radio telescopes, at 7mm and 4.4cm respectively, of the prototype Class 0 protostar VLA1623. At 7mm we detect two sources (VLA1623A & B) coincident with the two previously detected components at the centre of this system. The separation between the two is 1.2arcsec, or ~170AU at an assumed distance of 139pc. The upper limit to the size of the source coincident with each component of VLA1623 is ~0.7arcsec, in agreement with previous findings. This corresponds to a diameter of ~100AU at an assumed distance of 139pc. Both components show the same general trend in their broadband continuum spectra, of a steeper dust continuum spectrum shortward of 7mm and a flatter spectrum longward of this. We estimate an upper limit to the VLA1623A disc mass of <0.13Msol and an upper limit to its radius of ~50AU. The longer wavelength data have a spectral index of \alpha~0.6+/-0.3. This is too steep to be explained by optically thin free-free emission. It is most likely due to optically thick free-free emission. Alternatively, we speculate that it might be due to the formation of larger grains or planetesimals in the circumstellar disc. We estimate the mass of VLA1623B to be <0.15M$sol. We can place a lower limit to its size of ~30x7 AU, and an upper limit to its diameter of ~100AU. The longer wavelength data of VLA1623B also have a spectral index of \alpha~0.6+/-0.3. The nature of VLA1623B remains a matter of debate. It could be a binary companion to the protostar, or a knot in the radio jet from VLA1623A.Comment: 7 pages, 3 figures, 1 table, accepted for publication in MNRA

    Tumour-associated macrophages and oncolytic virotherapies:a mathematical investigation into a complex dynamics

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    Anti-cancer therapies based on oncolytic viruses are emerging as important approaches in cancer treatment. However, the effectiveness of these therapies depends significantly on the interactions between the oncolytic viruses and the host immune response. Macrophages are one of the most important cell types in the anti-viral immune responses, by acting as a first line of defence against infections. Here, we consider a mathematical approach to investigate the possible outcomes of the interactions between two extreme phenotypes of macrophages (M1 and M2 cells) and an oncolytic virus (VSV), in the context of B16F10 melanoma. We show that polarization towards either an M1 or M2 phenotype can enhance oncolytic virus therapy through either (i) anti-tumour immune activation, or (ii) enhanced oncolysis. Moreover, we show that tumour reduction and elimination does not depend only on the ratio of M1:M2 cells, but also on the number of tumour-infiltrating macrophages

    CARMA Large Area Star Formation Survey: Observational Analysis of Filaments in the Serpens South Molecular Cloud

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    We present the N2H+(J=1-0) map of the Serpens South molecular cloud obtained as part of the CARMA Large Area Star Formation Survey (CLASSy). The observations cover 250 square arcminutes and fully sample structures from 3000 AU to 3 pc with a velocity resolution of 0.16 km/s, and they can be used to constrain the origin and evolution of molecular cloud filaments. The spatial distribution of the N2H+ emission is characterized by long filaments that resemble those observed in the dust continuum emission by Herschel. However, the gas filaments are typically narrower such that, in some cases, two or three quasi-parallel N2H+ filaments comprise a single observed dust continuum filament. The difference between the dust and gas filament widths casts doubt on Herschel ability to resolve the Serpens South filaments. Some molecular filaments show velocity gradients along their major axis, and two are characterized by a steep velocity gradient in the direction perpendicular to the filament axis. The observed velocity gradient along one of these filaments was previously postulated as evidence for mass infall toward the central cluster, but these kind of gradients can be interpreted as projection of large-scale turbulence.Comment: 12 pages, 4 figures, published in ApJL (July 2014

    A Bima Array Survey of Molecules in Comets Linear (C/2002 T7) and Neat (C/2001 Q4)

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    We present an interferometric search for large molecules, including methanol, methyl cyanide, ethyl cyanide, ethanol, and methyl formate in comets LINEAR (C/2002 T7) and NEAT (C/2001 Q4) with the Berkeley-Illinois-Maryland Association (BIMA) array. In addition, we also searched for transitions of the simpler molecules CS, SiO, HNC, HN13C and 13CO . We detected transitions of methanol and CS around Comet LINEAR and one transition of methanol around Comet NEAT within a synthesized beam of ~20''. We calculated the total column density and production rate of each molecular species using the variable temperature and outflow velocity (VTOV) model described by Friedel et al.(2005).Considering the molecular production rate ratios with respect to water, Comet T7 LINEAR is more similar to Comet Hale-Bopp while Comet Q4 NEAT is more similar to Comet Hyakutake. It is unclear, however, due to such a small sample size, whether there is a clear distinction between a Hale-Bopp and Hyakutake class of comet or whether comets have a continuous range of molecular production rate ratios.Comment: Accepted for Publication in the Astrophysical Journa
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