A Tandem C-H Insertion—Acetal Cleavage Sequence: Stereocontrolled Synthesis of Substituted Tetrahydrofurans.

A short sequence involving Rh(II) mediated carbene insertion followed by Lewis acid promoted reductive acetal cleavage with Et3SiH provides a stereoselective method for the construction of 2,3,5-trisubstituted tetrahydrofuran rings

There is a riskreturn trade-off after all,”

Abstract This paper studies the ICAPM intertemporal relation between conditional mean and conditional variance of the aggregate stock market return. We introduce a new estimator that forecasts monthly variance with past daily squared returns -the Mixed Data Sampling (or MIDAS) approach. Using MIDAS, we find that there is a significantly positive relation between risk and return in the stock market. This finding is robust in subsamples, to asymmetric specifications of the variance process, and to controlling for variables associated with the business cycle. We compare the MIDAS results with other tests of the ICAPM based on alternative conditional variance specifications and explain the conflicting results in the literature. Finally, we offer new insights about the dynamics of conditional variance. * We than