The influence of social networks on the formation of the communicative competence of a modern young person

The purpose of the study is to identify the factors of influence of social networks on the communicative competence of a modern young person.Цель исследования – выявить факторы влияния социальных сетей на коммуникативную компетентность современного молодого человека

ОСОБЕННОСТИ ОБМЕНА БИОПОЛИМЕРОВ СОЕДИНИТЕЛЬНОЙ ТКАНИ В ПЕЧЕНИ КРЫС С АЛЛОКСАНОВЫМ ДИАБЕТОМ

Aim. Study of the exchange of liver and blood plasma biopolymers of alloxan diabetic rats.Materials and Methods. Diabetes mellitus was modeled in rats by single subcutaneous injection of alloxan tetrahydrate (170 mg per100 gbody weight). Blood glucose, glycosylated hemoglobin were controlled and morphometric study of the pancreas was carried out for the verification of the model. A month later, concentration of glycosaminoglycans, free hydroxyproline and the level of hyaluronidase and collagenolytic activity in plasma were determined. The total concentration of collagen, glycosaminoglycans, and their fractions, the level of hyaluronidase and collagenolytic activity in rat liver homogenate were measured.Results. The level of all the parameters of interest in the liver and blood plasma increased on 30 day after alloxan injection, the accumulation of glycosaminoglycans in the liver occurred mainly due to unsulfonated fraction.Conclusion. The development of experimental diabetes in rats is accompanied by activation of both decay processes and synthesis of biopolymers studied. Accumulation of total collagen and glycosaminoglycans was observed in rats’ liver, which probably lead to the fibrosis changes in it.Цель исследования – изучить особенности обмена биополимеров матрикса печени и плазмы крови крыс при аллоксановом диабете. Материал и методы. Сахарный диабет у крыс моделировали однократным подкожным введением аллоксана тетрагидрата в дозе 170 мг/кг массы тела животного (для верификации модели определяли в крови содержание глюкозы, гликозилированного гемоглобина, проводили морфометрическое исследование поджелудочной железы). Через 1 мес в плазме крови определяли концентрацию гликозаминогликанов, свободного гидроксипролина, уровень гиалуронидазной и коллагенолитической активности. В гомогенате печени крыс определяли концентрацию суммарного коллагена, гликозаминогликанов, их фракций, уровень гиалуронидазной и коллагенолитической активности. Результаты. На 30-е сут после введения аллоксана в плазме крови и печени крыс наблюдалось возрастание уровня всех исследуемых показателей, причем накопление гликозаминогликанов в печени происходило преимущественно за счет несульфатированной фракции. Заключение. Развитие экспериментального диабета у животных сопровождается активацией как процессов распада, так и синтеза исследуемых биополимеров. В печени крыс отмечается накопление суммарного коллагена и гликозаминогликанов, что, вероятно, служит причиной фиброзных изменений в исследуемом органе

Selection of the quantity of the allowance at rough treatment of large – size parts from titanium alloy of BT6 (Russian State Standard GOST 19807-91)

The article presents the results of experimental studies of the effect of cutting depth on cutting force and the procedure of assignment of allowance value at rough turning and melting of stamped blanks for large- size parts of rocket equipment from titanium alloy VT6. As a result of the studies carried out, empirical dependence of cutting force on cutting depth was obtained, and method of allocation of allowance value was created, which is very important in processing of large-size stamped blanks

Selection of the quantity of the allowance at rough treatment of large – size parts from titanium alloy of BT6 (Russian State Standard GOST 19807-91)

The article presents the results of experimental studies of the effect of cutting depth on cutting force and the procedure of assignment of allowance value at rough turning and melting of stamped blanks for large- size parts of rocket equipment from titanium alloy VT6. As a result of the studies carried out, empirical dependence of cutting force on cutting depth was obtained, and method of allocation of allowance value was created, which is very important in processing of large-size stamped blanks

THE EXCHANGE OF CONNECTIVE TISSUE BIOPOLYMERS IN THE LIVER OF ALLOXAN DIABETIC RATS

Aim. Study of the exchange of liver and blood plasma biopolymers of alloxan diabetic rats.Materials and Methods. Diabetes mellitus was modeled in rats by single subcutaneous injection of alloxan tetrahydrate (170 mg per100 gbody weight). Blood glucose, glycosylated hemoglobin were controlled and morphometric study of the pancreas was carried out for the verification of the model. A month later, concentration of glycosaminoglycans, free hydroxyproline and the level of hyaluronidase and collagenolytic activity in plasma were determined. The total concentration of collagen, glycosaminoglycans, and their fractions, the level of hyaluronidase and collagenolytic activity in rat liver homogenate were measured.Results. The level of all the parameters of interest in the liver and blood plasma increased on 30 day after alloxan injection, the accumulation of glycosaminoglycans in the liver occurred mainly due to unsulfonated fraction.Conclusion. The development of experimental diabetes in rats is accompanied by activation of both decay processes and synthesis of biopolymers studied. Accumulation of total collagen and glycosaminoglycans was observed in rats’ liver, which probably lead to the fibrosis changes in it