Pseudomicetoma felino causado por Microsporum canis: descripción de un caso clínico y su tratamiento

En la presente comunicación se describe un caso clínico de dermatofitosis en un gato persa, producida por Microsporum canis, con manifestaciones cutáneas de pseudomicetoma (granuloma de Majocchi). Se detallan los diagnósticos clínico e histopatológico, así como el tratamiento instaurado

Enhanced Thermal Object Imaging by Photon Addition or Subtraction

Long-baseline interferometry (LBI) is used to reconstruct the image of faint thermal objects. The image quality, for a given exposure time, is in general limited by a low signal-to-noise ratio (SNR). We show theoretically that a significant increase of the SNR, in a LBI, is possible by adding or subtracting photons to the thermal beam. At low photon counts, photon addition-subtraction technology strongly enhances the image quality. We have experimentally realized a nondeterministic physical protocol for photon subtraction. Our theoretical predictions are supported by experimental results.Comment: 4 pages, 5 figure

Pneumoproteins and biomarkers of inflammation and coagulation do not predict rapid lung function decline in people living with HIV

Chronic obstructive pulmonary disease (COPD) is among the leading causes of death worldwide and HIV is an independent risk factor for the development of COPD. However, the etiology of this increased risk and means to identify persons with HIV (PWH) at highest risk for COPD have remained elusive. Biomarkers may reveal etiologic pathways and allow better COPD risk stratification. We performed a matched case:control study of PWH in the Strategic Timing of Antiretoviral Treatment (START) pulmonary substudy. Cases had rapid lung function decline (> 40 mL/year FEV1 decline) and controls had stable lung function (+ 20 to − 20 mL/year). The analysis was performed in two distinct groups: (1) those who were virally suppressed for at least 6 months and (2) those with untreated HIV (from the START deferred treatment arm). We used linear mixed effects models to test the relationship between case:control status and blood concentrations of pneumoproteins (surfactant protein-D and club cell secretory protein), and biomarkers of inflammation (IL-6 and hsCRP) and coagulation (d-dimer and fibrinogen); concentrations were measured within ± 6 months of first included spirometry. We included an interaction with treatment group (untreated HIV vs viral suppression) to test if associations varied by treatment group. This analysis included 77 matched case:control pairs in the virally suppressed batch, and 42 matched case:control pairs in the untreated HIV batch (n = 238 total) who were followed for a median of 3 years. Median (IQR) CD4 + count was lowest in the controls with untreated HIV at 674 (580, 838). We found no significant associations between case:control status and pneumoprotein or biomarker concentrations in either virally suppressed or untreated PWH. In this cohort of relatively young, recently diagnosed PWH, concentrations of pneumoproteins and biomarkers of inflammation and coagulation were not associated with subsequent rapid lung function decline. Trial registration: NCT00867048 and NCT01797367

Larval development of Aelurostrongylus abstrusus in experimentally infected Rumina decollata snails

Aelurostrongylus abstrusus is a lungworm distributed worldwide that affects wild and domestic cats, causing bronchopneumonia of varying intensity. Snails serve as intermediate hosts. The aim of the present study was to assess the larval development of A. abstrusus in R. decollata snails and to investigate its potential as an intermediate host. For this purpose, first-stage larvae (L1) of A. abstrusus were obtained from the faeces of naturally infected cats. Doses of 500 L1/snail were given to 24 R. decollata snails, placed on the soil of the breeder chamber, and maintained under laboratory conditions. Three snails were killed at 8, 10, 12, 16, 22, 26, 45 and 55 days post-infection (dpi), and the muscular foot and visceral body were separately digested by an artificial digestion technique. The morphometric parameters of different larval stages were recorded. The mean number of larvae reaching the infective stage at the end of the study (L3) was 262 larvae/snail. The greatest development to L3 was recorded from days16 to 55 pi, during which the isolation was maximum. A. Abstrusus L3 were isolated from the viscera, but isolation from the snail foot was significantly higher. Our results showed for the first time the ability of A. Abstrusus larvae to develop in R. decollata, thus serving as a potential intermediate host

Changes in behavior among the College of Medical Laboratory Science students of De La Salle Medical and Health Sciences Institute before and after COVID-19 vaccination

During the peak of the COVID-19 pandemic, heightened restrictions coupled with personal health and preventive behaviors protect the public from acquiring the infection before the provision of COVID-19 vaccines. However, as COVID-19 vaccination becomes available to the public, there is an observable weakening of personal health and preventive behaviors as the restrictions weaken. This observation is important for students as they are now more exposed as face-to-face classes are being established again. In this study, we investigate if there is a significant change in COVID-19 related behaviors before and after COVID-19 vaccination among College of Medical Laboratory Science (CMLS) students of De La Salle Medical and Health Sciences Institute (DLSMHSI). We conducted a survey among 263 vaccinated students out of 808 total vaccinated students from first year to fourth year students using stratified random sampling for selecting the respondents, proportionate sampling for determining the sample size, and simple random sampling for determining the respondents per stratum. To maximize our results’ capacity to correlate with our objective, we embed quantitative and cross-sectional research design. Our analysis implied that all variables of COVID-19 related behaviors we measured significantly changed after COVID-19 vaccination from their behavior before COVID-19 vaccination. Additionally, only the proper handwashing and wearing of face masks remained the same after having COVID-19 vaccination. Based on the findings, the researchers recommend that the concerned institution continues establishing health protocols for students to reduce potential transmission of SARS-CoV-2. As some COVID-19-related behaviors begin to deteriorate, the likelihood of viral transmission may increase

Larval development of Aelurostrongylus abstrusus in experimentally infected Rumina decollata snails

Aelurostrongylus abstrusus is a lungworm distributed worldwide that affects wild and domestic cats, causing bronchopneumonia of varying intensity. Snails serve as intermediate hosts. The aim of the present study was to assess the larval development of A. abstrusus in R. decollata snails and to investigate its potential as an intermediate host. For this purpose, first-stage larvae (L1) of A. abstrusus were obtained from the faeces of naturally infected cats. Doses of 500 L1/snail were given to 24 R. decollata snails, placed on the soil of the breeder chamber, and maintained under laboratory conditions. Three snails were killed at 8, 10, 12, 16, 22, 26, 45 and 55 days post-infection (dpi), and the muscular foot and visceral body were separately digested by an artificial digestion technique. The morphometric parameters of different larval stages were recorded. The mean number of larvae reaching the infective stage at the end of the study (L3) was 262 larvae/snail. The greatest development to L3 was recorded from days16 to 55 pi, during which the isolation was maximum. A. Abstrusus L3 were isolated from the viscera, but isolation from the snail foot was significantly higher. Our results showed for the first time the ability of A. Abstrusus larvae to develop in R. decollata, thus serving as a potential intermediate host