Management of Wintering Short-eared Owls at Airports in the Lower Great Lakes Region

USDA Wildlife Services airport wildlife biologists have been tasked with reducing the hazards that raptors (including owls) pose to safe aircraft operations at airports and military airfields throughout the USA. A review of available wildlife strike information suggests short-eared owls (Asio flammeus) are frequently struck by aircraft during the winter months at numerous airports within the Lower Great Lakes Region of the United States. Further, this species is listed as ‘endangered’ by state fish and wildlife agencies in many states, although not at the federal level. Consequently, there is particular interest in developing non-lethal management tools for reducing the hazards posed by this species. In an effort to gain a better understanding of the efficacy of managing the hazards to aviation posed by short-eared owls, we developed methods to live-capture, mark with USGS aluminum leg bands, and translocate short-eared owls from airport environments (i.e., airfield areas) as part of the overall programs to reduce wildlife hazards to safe aircraft operations at airports. During 2012−2015, a total of 32 short-eared owls was live-captured, banded, and translocated to release sites approximately 64 to 80 km (40 to 50 miles) away from the airports. Only 1 short-eared owl (3%) was resighted and this bird was found on a different airport from where it had been translocated from. Future research in needed to evaluate the efficacy of translocating wintering short-eared owls from airport environments

Management of Wintering Short-eared Owls at Airports in the Lower Great Lakes Region

USDA Wildlife Services airport wildlife biologists have been tasked with reducing the hazards that raptors (including owls) pose to safe aircraft operations at airports and military airfields throughout the USA. A review of available wildlife strike information suggests short-eared owls (Asio flammeus) are frequently struck by aircraft during the winter months at numerous airports within the Lower Great Lakes Region of the United States. Further, this species is listed as ‘endangered’ by state fish and wildlife agencies in many states, although not at the federal level. Consequently, there is particular interest in developing non-lethal management tools for reducing the hazards posed by this species. In an effort to gain a better understanding of the efficacy of managing the hazards to aviation posed by short-eared owls, we developed methods to live-capture, mark with USGS aluminum leg bands, and translocate short-eared owls from airport environments (i.e., airfield areas) as part of the overall programs to reduce wildlife hazards to safe aircraft operations at airports. During 2012−2015, a total of 32 short-eared owls was live-captured, banded, and translocated to release sites approximately 64 to 80 km (40 to 50 miles) away from the airports. Only 1 short-eared owl (3%) was resighted and this bird was found on a different airport from where it had been translocated from. Future research in needed to evaluate the efficacy of translocating wintering short-eared owls from airport environments

Management of Wintering Short-eared Owls at Airports in the Lower Great Lakes Region

USDA Wildlife Services airport wildlife biologists have been tasked with reducing the hazards that raptors (including owls) pose to safe aircraft operations at airports and military airfields throughout the USA. A review of available wildlife strike information suggests short-eared owls (Asio flammeus) are frequently struck by aircraft during the winter months at numerous airports within the Lower Great Lakes Region of the United States. Further, this species is listed as ‘endangered’ by state fish and wildlife agencies in many states, although not at the federal level. Consequently, there is particular interest in developing non-lethal management tools for reducing the hazards posed by this species. In an effort to gain a better understanding of the efficacy of managing the hazards to aviation posed by short-eared owls, we developed methods to live-capture, mark with USGS aluminum leg bands, and translocate short-eared owls from airport environments (i.e., airfield areas) as part of the overall programs to reduce wildlife hazards to safe aircraft operations at airports. During 2012−2015, a total of 32 short-eared owls was live-captured, banded, and translocated to release sites approximately 64 to 80 km (40 to 50 miles) away from the airports. Only 1 short-eared owl (3%) was resighted and this bird was found on a different airport from where it had been translocated from. Future research in needed to evaluate the efficacy of translocating wintering short-eared owls from airport environments

Management of Wintering Short-eared Owls at Airports in the Lower Great Lakes Region

USDA Wildlife Services airport wildlife biologists have been tasked with reducing the hazards that raptors (including owls) pose to safe aircraft operations at airports and military airfields throughout the USA. A review of available wildlife strike information suggests short-eared owls (Asio flammeus) are frequently struck by aircraft during the winter months at numerous airports within the Lower Great Lakes Region of the United States. Further, this species is listed as ‘endangered’ by state fish and wildlife agencies in many states, although not at the federal level. Consequently, there is particular interest in developing non-lethal management tools for reducing the hazards posed by this species. In an effort to gain a better understanding of the efficacy of managing the hazards to aviation posed by short-eared owls, we developed methods to live-capture, mark with USGS aluminum leg bands, and translocate short-eared owls from airport environments (i.e., airfield areas) as part of the overall programs to reduce wildlife hazards to safe aircraft operations at airports. During 2012−2015, a total of 32 short-eared owls was live-captured, banded, and translocated to release sites approximately 64 to 80 km (40 to 50 miles) away from the airports. Only 1 short-eared owl (3%) was resighted and this bird was found on a different airport from where it had been translocated from. Future research in needed to evaluate the efficacy of translocating wintering short-eared owls from airport environments

Management of Wintering Short-eared Owls at Airports in the Lower Great Lakes Region

USDA Wildlife Services airport wildlife biologists have been tasked with reducing the hazards that raptors (including owls) pose to safe aircraft operations at airports and military airfields throughout the USA. A review of available wildlife strike information suggests short-eared owls (Asio flammeus) are frequently struck by aircraft during the winter months at numerous airports within the Lower Great Lakes Region of the United States. Further, this species is listed as ‘endangered’ by state fish and wildlife agencies in many states, although not at the federal level. Consequently, there is particular interest in developing non-lethal management tools for reducing the hazards posed by this species. In an effort to gain a better understanding of the efficacy of managing the hazards to aviation posed by short-eared owls, we developed methods to live-capture, mark with USGS aluminum leg bands, and translocate short-eared owls from airport environments (i.e., airfield areas) as part of the overall programs to reduce wildlife hazards to safe aircraft operations at airports. During 2012−2015, a total of 32 short-eared owls was live-captured, banded, and translocated to release sites approximately 64 to 80 km (40 to 50 miles) away from the airports. Only 1 short-eared owl (3%) was resighted and this bird was found on a different airport from where it had been translocated from. Future research in needed to evaluate the efficacy of translocating wintering short-eared owls from airport environments

Management of Wintering Short-eared Owls at Airports in the Lower Great Lakes Region

USDA Wildlife Services airport wildlife biologists have been tasked with reducing the hazards that raptors (including owls) pose to safe aircraft operations at airports and military airfields throughout the USA. A review of available wildlife strike information suggests short-eared owls (Asio flammeus) are frequently struck by aircraft during the winter months at numerous airports within the Lower Great Lakes Region of the United States. Further, this species is listed as ‘endangered’ by state fish and wildlife agencies in many states, although not at the federal level. Consequently, there is particular interest in developing non-lethal management tools for reducing the hazards posed by this species. In an effort to gain a better understanding of the efficacy of managing the hazards to aviation posed by short-eared owls, we developed methods to live-capture, mark with USGS aluminum leg bands, and translocate short-eared owls from airport environments (i.e., airfield areas) as part of the overall programs to reduce wildlife hazards to safe aircraft operations at airports. During 2012−2015, a total of 32 short-eared owls was live-captured, banded, and translocated to release sites approximately 64 to 80 km (40 to 50 miles) away from the airports. Only 1 short-eared owl (3%) was resighted and this bird was found on a different airport from where it had been translocated from. Future research in needed to evaluate the efficacy of translocating wintering short-eared owls from airport environments

Management of Wintering Short-eared Owls at Airports in the Lower Great Lakes Region

USDA Wildlife Services airport wildlife biologists have been tasked with reducing the hazards that raptors (including owls) pose to safe aircraft operations at airports and military airfields throughout the USA. A review of available wildlife strike information suggests short-eared owls (Asio flammeus) are frequently struck by aircraft during the winter months at numerous airports within the Lower Great Lakes Region of the United States. Further, this species is listed as ‘endangered’ by state fish and wildlife agencies in many states, although not at the federal level. Consequently, there is particular interest in developing non-lethal management tools for reducing the hazards posed by this species. In an effort to gain a better understanding of the efficacy of managing the hazards to aviation posed by short-eared owls, we developed methods to live-capture, mark with USGS aluminum leg bands, and translocate short-eared owls from airport environments (i.e., airfield areas) as part of the overall programs to reduce wildlife hazards to safe aircraft operations at airports. During 2012−2015, a total of 32 short-eared owls was live-captured, banded, and translocated to release sites approximately 64 to 80 km (40 to 50 miles) away from the airports. Only 1 short-eared owl (3%) was resighted and this bird was found on a different airport from where it had been translocated from. Future research in needed to evaluate the efficacy of translocating wintering short-eared owls from airport environments

Management of Wintering Short-Eared Owls at Airports in the Lower Great Lakes Region

USDA Wildlife Services airport wildlife biologists have been tasked with reducing the hazards that raptors (including owls) pose to safe aircraft operations at airports and military airfields throughout the USA. A review of available wildlife strike information suggests short-eared owls (Asio flammeus) are frequently struck by aircraft during the winter months at numerous airports within the Lower Great Lakes Region of the United States. Further, this species is listed as ‘endangered’ by state fish and wildlife agencies in many states, although not at the federal level. Consequently, there is particular interest in developing non-lethal management tools for reducing the hazards posed by this species. In an effort to gain a better understanding of the efficacy of managing the hazards to aviation posed by short-eared owls, we developed methods to live-capture, mark with USGS aluminum leg bands, and translocate short-eared owls from airport environments (i.e., airfield areas) as part of the overall programs to reduce wildlife hazards to safe aircraft operations at airports. During 2012−2015, a total of 32 short-eared owls was live-captured, banded, and translocated to release sites approximately 64 to 80 km (40 to 50 miles) away from the airports. Only 1 short-eared owl (3%) was resighted and this bird was found on a different airport from where it had been translocated from. Future research in needed to evaluate the efficacy of translocating wintering short-eared owls from airport environments

Hepatitis C Virus Core Protein Induces Neuroimmune Activation and Potentiates Human Immunodeficiency Virus-1 Neurotoxicity

BACKGROUND: Hepatitis C virus (HCV) genomes and proteins are present in human brain tissues although the impact of HIV/HCV co-infection on neuropathogenesis remains unclear. Herein, we investigate HCV infectivity and effects on neuronal survival and neuroinflammation in conjunction with HIV infection. METHODOLOGY: Human microglia, astrocyte and neuron cultures were infected with cell culture-derived HCV or exposed to HCV core protein with or without HIV-1 infection or HIV-1 Viral Protein R (Vpr) exposure. Host immune gene expression and cell viability were measured. Patch-clamp studies of human neurons were performed in the presence or absence of HCV core protein. Neurobehavioral performance and neuropathology were examined in HIV-1 Vpr-transgenic mice in which stereotaxic intrastriatal implants of HCV core protein were performed. PRINCIPAL FINDINGS: HCV-encoded RNA as well as HCV core and non-structural 3 (NS3) proteins were detectable in human microglia and astrocytes infected with HCV. HCV core protein exposure induced expression of pro-inflammatory cytokines including interleukin-1β, interleukin-6 and tumor necrosis factor-α in microglia (p<0.05) but not in astrocytes while increased chemokine (e.g. CXCL10 and interleukin-8) expression was observed in both microglia and astrocytes (p<0.05). HCV core protein modulated neuronal membrane currents and reduced both β-III-tubulin and lipidated LC3-II expression (p<0.05). Neurons exposed to supernatants from HCV core-activated microglia exhibited reduced β-III-tubulin expression (p<0.05). HCV core protein neurotoxicity and interleukin-6 induction were potentiated by HIV-1 Vpr protein (p<0.05). HIV-1 Vpr transgenic mice implanted with HCV core protein showed gliosis, reduced neuronal counts together with diminished LC3 immunoreactivity. HCV core-implanted animals displayed neurobehavioral deficits at days 7 and 14 post-implantation (p<0.05). CONCLUSIONS: HCV core protein exposure caused neuronal injury through suppression of neuronal autophagy in addition to neuroimmune activation. The additive neurotoxic effects of HCV- and HIV-encoded proteins highlight extrahepatic mechanisms by which HCV infection worsens the disease course of HIV infection

Multisystem Inflammatory Syndrome in Children — Initial Therapy and Outcomes

This article is made available for unrestricted research re-use and secondary analysis in any form or be any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.Background: The assessment of real-world effectiveness of immunomodulatory medications for multisystem inflammatory syndrome in children (MIS-C) may guide therapy. Methods: We analyzed surveillance data on inpatients younger than 21 years of age who had MIS-C and were admitted to 1 of 58 U.S. hospitals between March 15 and October 31, 2020. The effectiveness of initial immunomodulatory therapy (day 0, indicating the first day any such therapy for MIS-C was given) with intravenous immune globulin (IVIG) plus glucocorticoids, as compared with IVIG alone, was evaluated with propensity-score matching and inverse probability weighting, with adjustment for baseline MIS-C severity and demographic characteristics. The primary outcome was cardiovascular dysfunction (a composite of left ventricular dysfunction or shock resulting in the use of vasopressors) on or after day 2. Secondary outcomes included the components of the primary outcome, the receipt of adjunctive treatment (glucocorticoids in patients not already receiving glucocorticoids on day 0, a biologic, or a second dose of IVIG) on or after day 1, and persistent or recurrent fever on or after day 2. Results: A total of 518 patients with MIS-C (median age, 8.7 years) received at least one immunomodulatory therapy; 75% had been previously healthy, and 9 died. In the propensity-score-matched analysis, initial treatment with IVIG plus glucocorticoids (103 patients) was associated with a lower risk of cardiovascular dysfunction on or after day 2 than IVIG alone (103 patients) (17% vs. 31%; risk ratio, 0.56; 95% confidence interval [CI], 0.34 to 0.94). The risks of the components of the composite outcome were also lower among those who received IVIG plus glucocorticoids: left ventricular dysfunction occurred in 8% and 17% of the patients, respectively (risk ratio, 0.46; 95% CI, 0.19 to 1.15), and shock resulting in vasopressor use in 13% and 24% (risk ratio, 0.54; 95% CI, 0.29 to 1.00). The use of adjunctive therapy was lower among patients who received IVIG plus glucocorticoids than among those who received IVIG alone (34% vs. 70%; risk ratio, 0.49; 95% CI, 0.36 to 0.65), but the risk of fever was unaffected (31% and 40%, respectively; risk ratio, 0.78; 95% CI, 0.53 to 1.13). The inverse-probability-weighted analysis confirmed the results of the propensity-score-matched analysis. Conclusions: Among children and adolescents with MIS-C, initial treatment with IVIG plus glucocorticoids was associated with a lower risk of new or persistent cardiovascular dysfunction than IVIG alone. (Funded by the Centers for Disease Control and Prevention.)