17 research outputs found

    West London first-episode study of schizophrenia - clinical correlates of duration of untreated psychosis

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    Background: Studies in schizophrenia suggest that a longer initial period of untreated illness is associated with a poorer clinical outcome. Aims: To determine whether, in first-episode schizophrenia, a longer duration of untreated psychosis (DUP) or of untreated illness (DUI) (DUP plus any prodrome) is associated with clinical variables that could mediate a poor prognosis. Method: Clinical, social, neuropsychological and oculomotor function data on 53 patients with first-episode schizophrenia were related to the DUP and DUI. Results: Comparing short and long DUP groups split around the median showed no statistically significant differences (except age); patients in the latter group tended to perform worse on an executive attentional set-shifting task, and were more likely to be unemployed, and living alone or homeless. Conclusions: There was little evidence of any association between either DUP or DUI and progressive deterioration in the schizophrenic illness or the development of resistance to initial drug treatment. Social variables that augur a poor prognosis may be associated with delayed presentation of schizophrenia to psychiatric services. Declaration of interest: Supported by the Wellcome Trust

    Flying Foxes (Chiroptera: Pteropodidae): Threatened Animals of Key Ecological and Economic Importance

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    Flying foxes are animals of extraordinary ecological and economic importance throughout forests of the Old World tropics Nearly 200 species play an essential role as forest pollinators and seed dispersers, yet they are frequently misunderstood intensely persecuted and exceptionally vulnerable to extinction Their role in the propagation of numerous important plants remains virtually uninvestigated. However, our review of already available literature demonstrates that at least 289 plant species rely to vatying degrees on large populations of flying foxes for propagation. These plants, in addition to their many ecological contributing produce some 448 economically valuable products. The fact that flying foxes are increasingly threaten and that few baseline data exist on population trends is cause for concern Many appear to be in severe decline, and several species are already extinct. We present initial observations on flying fox importance and survival threats in hopes of highlighting research and conservation needs
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