43 research outputs found
An observational study on oesophageal variceal endoscopic injection sclerotherapy in patients with portal hypertension seen at the Centre for Clinical Research, Kenya Medical Research Institute
Bleeding oesophageal varices still remain a common cause of significant
morbidity and mortality in Kenya and is the leading cause of upper
gastrointestinal haemorrhage as seen at Kenyatta National Hospital,
Nairobi. We report on our experiences in the management of oesophageal
varices using injection sclerotherapy. The study site was the Centre
for Clinical Research, Kenya Medical Research Institute (KEMRI).
Records from structured reporting on procedures and findings during
oesophageal variceal injection sclerotherapy were reviewed. All the
patients with portal hypertension and previous history of acute
variceal blood who underwent endoscopic injection sclerotherapy between
August 1998 and May 2001 in the endoscopy unit, KEMRI, had between 2
and 8 sessions of sclerotherapy with 10-15 ml of 5% ethanolamine oleate
during each session. The injection sclerotherapy was done under
sedation and pharyngeal local anaesthesia. This was followed by regular
surveillance endoscopic examination at 1,3,6 months then yearly. A
total of 112 patients underwent vericeal injection sclerotherapy. Male:
Female of 2:2:1 and mean age was 32.8 \ub1 3.3 years. Eighty-five
(75.9%) of the patients received at least 4 sessions of injections
sclerotherapy. 82.4% of those who received sclerotherapy upto 4
sessions had regression of varices and 15% of patients\u2019 required
more than 6 sessions. The report concludes that variceal injection
sclerotherapy is a useful method of treating oesophageal varices and
can be performed on an out patient basis