Information, information processing and gravity

I discuss fundamental limits placed on information and information processing by gravity. Such limits arise because both information and its processing require energy, while gravitational collapse (formation of a horizon or black hole) restricts the amount of energy allowed in a finite region. Specifically, I use a criterion for gravitational collapse called the hoop conjecture. Once the hoop conjecture is assumed a number of results can be obtained directly: the existence of a fundamental uncertainty in spatial distance of order the Planck length, bounds on information (entropy) in a finite region, and a bound on the rate of information processing in a finite region. In the final section I discuss some cosmological issues related to the total amount of information in the universe, and note that almost all detailed aspects of the late universe are determined by the randomness of quantum outcomes. This paper is based on a talk presented at a 2007 Bellairs Research Institute (McGill University) workshop on black holes and quantum information.Comment: 7 pages, 5 figures, revte

Journal of African Christian Biography: v. 1, no. 2

A publication of the Dictionary of African Christian Biography with U.S. offices located at the Center for Global Christianity and Mission at Boston University. This issue focuses on: 1. Bishop Josiah Kibira of Tanzania, Ecumenical Statesman. 2. Josiah Mutabuzi Isaya Kibira. 3. Josiah Kibira. 4. Recent Print and Digital Resources Related to Christianity in Africa

Efficient Bayesian Nonparametric Modelling of Structured Point Processes

This paper presents a Bayesian generative model for dependent Cox point processes, alongside an efficient inference scheme which scales as if the point processes were modelled independently. We can handle missing data naturally, infer latent structure, and cope with large numbers of observed processes. A further novel contribution enables the model to work effectively in higher dimensional spaces. Using this method, we achieve vastly improved predictive performance on both 2D and 1D real data, validating our structured approach.Comment: Presented at UAI 2014. Bibtex: @inproceedings{structcoxpp14_UAI, Author = {Tom Gunter and Chris Lloyd and Michael A. Osborne and Stephen J. Roberts}, Title = {Efficient Bayesian Nonparametric Modelling of Structured Point Processes}, Booktitle = {Uncertainty in Artificial Intelligence (UAI)}, Year = {2014}

Activation of σ28-dependent transcription inEscherichia coliby the cyclic AMP receptor protein requires an unusual promoter organization

The Escherichia coli aer regulatory region contains a single promoter that is recognized by RNA polymerase containing the flagellar sigma factor, σ28. Expression from this promoter is dependent on direct activation by the cyclic AMP receptor protein, which binds to a target centred 49.5 base pairs upstream from the transcript start. Activator-dependent transcription from the aer promoter was reconstituted in vitro, and a tethered inorganic nuclease was used to find the position of the C-terminal domains of the RNA polymerase α subunits in transcriptionally competent open complexes. We report that the ternary activator-RNA polymerase-aer promoter open complex is organized differently from complexes at previously characterized promoters. Among other E. coli promoters recognized by RNA polymerase containing σ28, only the trg promoter is activated directly by the cyclic AMP receptor protein. The organization of the different promoter elements and the activator binding site at the trg promoter is the same as at the aer promoter, suggesting a common activation mechanism

SN 1987A's Circumstellar Envelope, II: Kinematics of the Three Rings and the Diffuse Nebula

We present several different measurements of the velocities of structures within the circumstellar envelope of SN 1987A, including the inner, equatorial ring (ER), outer rings (ORs), and the diffuse nebulosity at radii < 5 pc, based on CTIO 4m and HST data. A comparison of STIS and WFPC2 [N II]6583 loci for the rings show that the ER is expanding in radius at 10.5+-0.3 km/s, with the northern OR expanding along the line of sight at about 26 km/s, and for the southern OR, about 23 km/s. Similar results are found with CTIO 4m data. Accounting for inclination, the best fit to all data show both ORs with an expansion from the SN of 26 km/s. The ratio of the ER to OR velocities is nearly equal to the ratio of ER to OR radii, so the rings are roughly homologous, all having kinematic ages corresponding to about 20,000 yr before the SN explosion. This makes previously reported, large compositional differences between the ER and ORs difficult to understand. Additionally, a grid of longslit 4m/echelle spectra centered on the SN shows two velocity components over a region roughly coextensive with the outer circumstellar envelope extending about 5 pc (20 arcsec) from the SN. One component is blueshifted and the other redshifted from the SN centroid by about 10 km/s each. These features may represent a bipolar flow expanding from the SN, in which the ORs are propelled 10-15 km/s faster than that of the surrounding envelope into which they propogate. The kinematic timescale for the entire nebula is at least about 350,000 yr. The kinematics of these various structures constrain possible models for the evolution of the progenitor and its formation of a mass loss nebula.Comment: 25 pages AASTeX text plus 12 figures. ApJ, in pres

Agouti C57BL/6N embryonic stem cells for mouse genetic resources.

We report the characterization of a highly germline competent C57BL/6N mouse embryonic stem cell line, JM8. To simplify breeding schemes, the dominant agouti coat color gene was restored in JM8 cells by targeted repair of the C57BL/6 nonagouti mutation. These cells provide a robust foundation for large-scale mouse knockout programs that aim to provide a public resource of targeted mutations in the C57BL/6 genetic background

TEDI: the TripleSpec Exoplanet Discovery Instrument

The TEDI (TripleSpec - Exoplanet Discovery Instrument) will be the first instrument fielded specifically for finding low-mass stellar companions. The instrument is a near infra-red interferometric spectrometer used as a radial velocimeter. TEDI joins Externally Dispersed Interferometery (EDI) with an efficient, medium-resolution, near IR (0.9 - 2.4 micron) echelle spectrometer, TripleSpec, at the Palomar 200" telescope. We describe the instrument and its radial velocimetry demonstration program to observe cool stars.Comment: 6 Pages, To Appear in SPIE Volume 6693, Techniques and Instrumentation for Detection of Exoplanets II

The Stereochemistry of trans-4-Hydroxynonenal-Derived Exocyclic 1,N2-2′-Deoxyguanosine Adducts Modulates Formation of Interstrand Cross-Links in the 5′-CpG-3′ Sequence†

ABSTRACT: The trans-4-hydroxynonenal (HNE)-derived exocyclic 1,N2-dG adduct with (6S,8R,11S) stereochemistry forms interstrand N2-dG-N2-dG cross-links in the 5′-CpG-3 ′ DNA sequence context, but the corresponding adduct possessing (6R,8S,11R) stereochemistry does not. Both exist primarily as diastereomeric cyclic hemiacetals when placed into duplex DNA [Huang, H., Wang, H., Qi, N., Kozekova

Universal continuous-variable quantum computation: Requirement of optical nonlinearity for photon counting

Although universal continuous-variable quantum computation cannot be achieved via linear optics (including squeezing), homodyne detection and feed-forward, inclusion of ideal photon counting measurements overcomes this obstacle. These measurements are sometimes described by arrays of beam splitters to distribute the photons across several modes. We show that such a scheme cannot be used to implement ideal photon counting and that such measurements necessarily involve nonlinear evolution. However, this requirement of nonlinearity can be moved "off-line," thereby permitting universal continuous-variable quantum computation with linear optics.Comment: 6 pages, no figures, replaced with published versio