1,456 research outputs found

    PDB31 The Prevalence and Burden of Comorbid Hypertension and Obesity Among Patients With Type 2 Diabetes in Urban China

    Get PDF

    Microcanonical Jet-fragmentation in proton-proton collisions at LHC Energy

    Get PDF
    In this paper, we show that the distribution of the longitudinal momentum fraction of charged hadrons dN/dzdN/dz inside jets stemming from proton-proton collisions at s\sqrt{s} = 7 TeV center of mass energy can be described by a statistical jet-fragmentation model. This model combines microcanonical statistics and super-statistics induced by multiplicity fluctuations. The resulting scale dependence of the parameters of the model turns out to be similar to what was observed in electron-positron annihilations in Urmossy, Barnaf\"oldi, and Bir\'o.Comment: 7 pages, 8 figure

    Simultaneous Diagonal and Off Diagonal Order in the Bose--Hubbard Hamiltonian

    Full text link
    The Bose-Hubbard model exhibits a rich phase diagram consisting both of insulating regimes where diagonal long range (solid) order dominates as well as conducting regimes where off diagonal long range order (superfluidity) is present. In this paper we describe the results of Quantum Monte Carlo calculations of the phase diagram, both for the hard and soft core cases, with a particular focus on the possibility of simultaneous superfluid and solid order. We also discuss the appearance of phase separation in the model. The simulations are compared with analytic calculations of the phase diagram and spin wave dispersion.Comment: 28 pages plus 24 figures, uuencoded Revtex+postscript file

    Interaction between androgen receptor and coregulator SLIRP is regulated by Ack1 tyrosine kinase and androgen

    Get PDF
    Aberrant activation of the androgen receptor (AR) may play a critical role in castration resistant prostate cancer. After ligand binding, AR is recruited to the androgen responsive element (ARE) sequences on the DNA where AR interaction with coactivators and corepressors modulates transcription. We demonstrated that phosphorylation of AR at Tyr-267 by Ack1/TNK2 tyrosine kinase results in nuclear translocation, DNA binding, and androgen-dependent gene transcription in a low androgen environment. In order to dissect downstream mechanisms, we searched for proteins whose interaction with AR was regulated by Ack1. SLIRP (SRA stem-loop interacting RNA binding protein) was identified as a candidate protein. Interaction between AR and SLIRP was disrupted by Ack1 kinase activity as well as androgen or heregulin treatment. The noncoding RNA, SRA, was required for AR-SLIRP interaction. SLIRP was bound to ARE’s of AR target genes in the absence of androgen. Treatment with androgen or heregulin led to dissociation of SLIRP from the ARE. Whole transcriptome analysis of SLIRP knockdown in androgen responsive LNCaP cells showed that SLIRP affects a significant subset of androgen-regulated genes. Our data suggest that Ack1 kinase and androgen regulate interaction between AR and SLIRP and that SLIRP functions as a coregulator of AR with properties of a corepressor in a context-dependent manner

    Sub-barrier capture with quantum diffusion approach: actinide-based reactions

    Full text link
    With the quantum diffusion approach the behavior of capture cross sections and mean-square angular momenta of captured systems are revealed in the reactions with deformed nuclei at subbarrier energies. The calculated results are in a good agreement with existing experimental data. With decreasing bombarding energy under the barrier the external turning point of the nucleusnucleus potential leaves the region of short-range nuclear interaction and action of friction. Because of this change of the regime of interaction, an unexpected enhancement of the capture cross section is expected at bombarding energies far below the Coulomb barrier. This effect is shown its worth in the dependence of mean-square angular momentum of captured system on the bombarding energy. From the comparison of calculated and experimental capture cross sections, the importance of quasifission near the entrance channel is shown for the actinide-based reactions leading to superheavy nuclei.Comment: 11 pages, 16 figures, Regular Articl

    Four-point Functions of Lowest Weight CPOs in N=4 SYM_4 in Supergravity Approximation

    Get PDF
    We show that the recently found quartic action for the scalars from the massless graviton multiplet of type IIB supergravity compactified on AdS_5\times S^5 background coincides with the relevant part of the action of the gauged N=8 5d supergravity on AdS_5. We then use this action to compute the 4-point function of the lowest weight chiral primary operators \tr(\phi^{(i}\phi^{j)}) in N=4 SYM_4 at large NN and at strong `t Hooft coupling.Comment: Latex, 21p, misprints are correcte

    Stars in five dimensional Kaluza Klein gravity

    Full text link
    In the five dimensional Kaluza Klein (KK) theory there is a well known class of static and electromagnetic--free KK--equations characterized by a naked singularity behavior, namely the Generalized Schwarzschild solution (GSS). We present here a set of interior solutions of five dimensional KK--equations. These equations have been numerically integrated to match the GSS in the vacuum. The solutions are candidates to describe the possible interior perfect fluid source of the exterior GSS metric and thus they can be models for stars for static, neutral astrophysical objects in the ordinary (four dimensional) spacetime.Comment: 15 pages, 8 figures. To be published in EPJ

    Nucleon Axial Form Factor from Lattice QCD

    Full text link
    Results for the isovector axial form factors of the proton from a lattice QCD calculation are presented for both point-split and local currents. They are obtained on a quenched 163×2416^{3} \times 24 lattice at ÎČ=6.0\beta= 6.0 with Wilson fermions for a range of quark masses from strange to charm. We determine the finite lattice renormalization for both the local and point-split currents of heavy quarks. Results extrapolated to the chiral limit show that the q2q^2 dependence of the axial form factor agrees reasonably well with experiment. The axial coupling constant gAg_A calculated for the local and the point-split currents is about 6\% and 12\% smaller than the experimental value respectively.Comment: 8 pages, 5 figures (included in part 2), UK/93-0

    Critical Behavior of the Supersolid transition in Bose-Hubbard Models

    Full text link
    We study the phase transitions of interacting bosons at zero temperature between superfluid (SF) and supersolid (SS) states. The latter are characterized by simultaneous off-diagonal long-range order and broken translational symmetry. The critical phenomena is described by a long-wavelength effective action, derived on symmetry grounds and verified by explicit calculation. We consider two types of supersolid ordering: checkerboard (X) and collinear (C), which are the simplest cases arising in two dimensions on a square lattice. We find that the SF--CSS transition is in the three-dimensional XY universality class. The SF--XSS transition exhibits non-trivial new critical behavior, and appears, within a d=3−ϔd=3-\epsilon expansion to be driven generically first order by fluctuations. However, within a one--loop calculation directly in d=2d=2 a strong coupling fixed point with striking ``non-Bose liquid'' behavior is found. At special isolated multi-critical points of particle-hole symmetry, the system falls into the 3d Ising universality class.Comment: RevTeX, 24 pages, 16 figures. Also available at http://www.cip.physik.tu-muenchen.de/tumphy/d/T34/Mitarbeiter/frey.htm

    Oscillations of a solid sphere falling through a wormlike micellar fluid

    Full text link
    We present an experimental study of the motion of a solid sphere falling through a wormlike micellar fluid. While smaller or lighter spheres quickly reach a terminal velocity, larger or heavier spheres are found to oscillate in the direction of their falling motion. The onset of this instability correlates with a critical value of the velocity gradient scale Γc∌1\Gamma_{c}\sim 1 s−1^{-1}. We relate this condition to the known complex rheology of wormlike micellar fluids, and suggest that the unsteady motion of the sphere is caused by the formation and breaking of flow-induced structures.Comment: 4 pages, 4 figure
    • 

    corecore