Use acupuncture to relieve perimenopausal syndrome: study protocol of a randomized controlled trial

Law Number 11 / 2008 on Information and Electronic Transaction (UU ITE) is the regulation concerning on criminal law in addition to the Criminal Code (KUHP). UU ITE is commonly regarded additional regulation of the Criminal Code as a special law (lex specialis) in which Penal Code is deemed as lex generalis. It is based on the principle of lex specialis derogate legi generalis. This article uses legal research to review the decision of District Court in Bandung Number 1033/PID.B/2014/PN.BDG where it comprises legislation and cases. It concludes that the judge is not frugal in applying the principle lex specialis derogat legi generalis in the consideration. This is associated with the indictment of public prosecutor which only prejudges with article 303 paragraph (1) to 2. In contrast, the indictment which does not meet the requirement of a careful, clear, and complete description asserts to become void by law. Keywords: Online Gambling, Criminal Principle, Indictmen

Advances in Studies on Toxicity and Transformation of Zearalenone and Its Derivatives

Zearalenone (ZEN) is a mycotoxin produced by the Fusarium species, which has various toxic effects. The chemical structures of ZEN and its derivatives are similar to that of estrogen. When ingested by animals or humans, ZEN and its derivatives can lead to disturbance of estrogen balance, thereby harming the reproductive system. Moreover, they can alter gene structure and consequently affect gene expression, and can even cause damage to the immune system, thus weakening the immune response. ZEN is transformed and metabolized into ZEN derivatives during food processing or after absorption by animals and plants, and its toxicity is altered due to structural and physicochemical changes. Studying the toxicity of ZEN and its derivatives as well as their transformation and metabolism in various organisms is important for ensuring food security and mycotoxin toxicity risk assessment

Stereotactic Body Radiation Therapy for Primary and Metastatic Liver Tumors

AbstractOBJECTIVES: The full potential of stereotactic body radiation therapy (SBRT), in the treatment of unresectable intrahepatic malignancies, has yet to be realized as our experience is still limited. Thus, we evaluated SBRT outcomes for primary and metastatic liver tumors, with the goal of identifying factors that may aid in optimization of therapy. METHODS: From2005 to 2010, 62 patients with 106 primary and metastatic liver tumors were treated with SBRT to a median biologic effective dose (BED) of 100 Gy (42.6-180). The majority of patients received either three (47%) or five fractions (48%). Median gross tumor volume (GTV) was 8.8 cm3 (0.2-222.4). RESULTS: With a median followup of 18 months (0.46-46.8), freedom from local progression (FFLP) was observed in 97 of 106 treated tumors, with 1- and 2-year FFLP rates of 93% and 82%. Median overall survival (OS) for all patients was 25.2 months, with 1- and 2-year OS of 81%and 52%. Neither BED nor GTV significantly predicted for FFLP. Local failure was associated with a higher risk of death [hazard ratio (HR) = 5.1, P = .0007]. One Child-Pugh Class B patient developed radiationinduced liver disease. There were no other significant toxicities. CONCLUSIONS: SBRT provides excellent local control for both primary and metastatic liver lesions with minimal toxicity. Future studies should focus on appropriate selection of patients and on careful assessment of liver function to maximize both the safety and efficacy of treatment

Fusion and Correction of Multi-Source Land Cover Products Based on Spatial Detection and Uncertainty Reasoning Methods in Central Asia

Land cover products are an indispensable data source in land surface process research, and their accuracy directly affects the reliability of related research. Due to the differences in factors such as satellite sensors, the temporal–spatial resolution of remote sensing images, and landcover interpretation technologies, various recently released land cover products are inconsistent, and their accuracy is usually insufficient to meet application requirements. This study, therefore, established a fusion and correction method for multi-source landcover products by combining them with landcover statistics from the Food and Agriculture Organization of the United Nations (FAO), introducing a spatial consistency discrimination technique, and applying an improved Dempster-Shafer evidence fusion method. The five countries in Central Asia were used for a method application and verification assessment. The nine products selected (CCI-LC, CGLS, FROM-GLC, GLCNMO, MCD12Q, GFSAD30, PALSAR, GSWD, and GHS-BUILT) were consistent in time and covered the study area. Based on the interpretation of 1437 high-definition image verification areas, the overall accuracy of the fusion landcover result was 85.32%, and the kappa coefficient was 0.80, which was better than that of the existing comprehensive products. The spatial consistency fusion method had the advantage of an improved statistical fitting, with an overall similarity statistic of 0.999. The improved Dempster-Shafer evidence theory fusion method had an accuracy that was 4.86% higher than the spatial consistency method, and the kappa coefficient increased by 0.07. Combining these two methods improved the consistency of the multi-source data fusion and correction method established in this paper and will also provide more reliable basic data for future research in Central Asia

Fusion and Correction of Multi-Source Land Cover Products Based on Spatial Detection and Uncertainty Reasoning Methods in Central Asia

Land cover products are an indispensable data source in land surface process research, and their accuracy directly affects the reliability of related research. Due to the differences in factors such as satellite sensors, the temporal–spatial resolution of remote sensing images, and landcover interpretation technologies, various recently released land cover products are inconsistent, and their accuracy is usually insufficient to meet application requirements. This study, therefore, established a fusion and correction method for multi-source landcover products by combining them with landcover statistics from the Food and Agriculture Organization of the United Nations (FAO), introducing a spatial consistency discrimination technique, and applying an improved Dempster-Shafer evidence fusion method. The five countries in Central Asia were used for a method application and verification assessment. The nine products selected (CCI-LC, CGLS, FROM-GLC, GLCNMO, MCD12Q, GFSAD30, PALSAR, GSWD, and GHS-BUILT) were consistent in time and covered the study area. Based on the interpretation of 1437 high-definition image verification areas, the overall accuracy of the fusion landcover result was 85.32%, and the kappa coefficient was 0.80, which was better than that of the existing comprehensive products. The spatial consistency fusion method had the advantage of an improved statistical fitting, with an overall similarity statistic of 0.999. The improved Dempster-Shafer evidence theory fusion method had an accuracy that was 4.86% higher than the spatial consistency method, and the kappa coefficient increased by 0.07. Combining these two methods improved the consistency of the multi-source data fusion and correction method established in this paper and will also provide more reliable basic data for future research in Central Asia

Analysis of Spatiotemporal Dynamics of the Chinese Vegetation Net Primary Productivity from the 1960s to the 2000s

Field net primary productivity (NPP) is useful in research modeling of regional and global carbon cycles and for validating results by remote sensing or process-based models. In this study, we used multiple models of NPP estimation and vegetation classification methods to study Chinese vegetation NPP characteristics, trends, and drivers using 7618 field measurements from the 1960s, 1980s, and 2000s. The values of other relevant NPP models, as well as process-based simulation and remote sensing models, were compared. Our results showed that NPP ranged from 3 to 12,407 gC·m−2·year−1 with a mean value of 571 gC·m−2·year−1. Vegetation NPP gradually decreased from the southeast to the northwest. Forest, farmland, and grassland NPP was 1152, 294, and 518 gC·m−2·year−1, respectively. Total NPP of grassland was higher than that of farmland. Total terrestrial NPP decreased from 3.58 to 3.41 Pg C·year−1 from the 1960s to the 2000s, a decadal decrease of 4.7%. Total NPP in forests and grasslands consistently showed a decreasing trend and decreased by 0.46 Pg C·year−1and 0.16 Pg C·year−1, respectively, whereas NPP for farmland showed an opposite trend, with a growth of 0.45 Pg C·year−1. Our research findings filled gaps in the information regarding NPP for the entire landmass of China based on field data from a long-term time series and provide valuable information and a basis for validation analyses by remote sensing models, as well as a robust quantification of carbon estimation to anticipate future development at the national and global scale

Reduction of Deoxynivalenol in Wheat with Superheated Steam and Its Effects on Wheat Quality

Deoxynivalenol (DON) is the most commonly found mycotoxin in scabbed wheat. In order to reduce the DON concentration in scabbed wheat with superheated steam (SS) and explore the feasibility to use the processed wheat as crisp biscuit materials, wheat kernels were treated with SS to study the effects of SS processing on DON concentration and the quality of wheat. Furthermore, the wheat treated with SS were used to make crisp biscuits and the texture qualities of biscuits were measured. The results showed that DON in wheat kernels could be reduced by SS effectively. Besides, the reduction rate raised significantly with the increase of steam temperature and processing time and it was also affected significantly by steam velocity. The reduction rate in wheat kernels and wheat flour could reach 77.4% and 60.5% respectively. In addition, SS processing might lead to partial denaturation of protein and partial gelatinization of starch, thus affecting the rheological properties of dough and pasting properties of wheat flour. Furthermore, the qualities of crisp biscuits were improved at certain conditions of SS processing

Natural and semi-natural land dynamics under water resource change from 1990 to 2015 in the Tarim Basin, China

The Tarim Basin is a typical arid area and has the world’s most severe desertification of natural and semi-natural land due to limited water resources. However, knowledge about the impacts of changes in water resources on the spatio-temporal dynamics of natural and semi-natural land is still limited. We analyzed the spatio-temporal changes in natural and semi-natural land and the associations with desertification in the Tarim Basin during the period 1990–2015. We then investigated the changes in water resources and the consequent impacts on the spatio-temporal changes of natural and semi-natural land by integrating Gravity Recovery and Climate Experiment territorial water storage data and field observations. The results showed that a total area of 10.32 × 10 ^3 km ^2 of natural and semi-natural land was converted to desert during the period 1990–2015. Desert vegetation type and saline type were the natural and semi-natural land types most sensitive to conversion to desert. The area of natural and semi-natural land decreased by 0.83% every year, and the proportion of desertified land was 34.79% on average during the period 2000–2010; this is less than for the period 1990–2000 (1.14% yr ^−1 and 52.01%) due to increased availability of water resources from the water conveyance program. However, the rate of decrease of natural and semi-natural land area (0.93% yr ^−1 ) and the proportion of desertified land (58.88%) rose again during the period 2010–2015 due to the rapid decrease in water resources. During the period 2000–2015, the rate of loss of natural and semi-natural land area (7.89%) in the region with decreased water resources was about twice that in the region with increased water resources (3.88%), highlighting the critical role of water resources in maintaining natural and semi-natural land and slowing desertification