598 research outputs found
Beyond Burritos and Lumpia: Ethnic Identity as a Difference in Preservice Teacher Education
Teachers play a pivotal role in society. On a daily basis they influence the futures of the children they encounter. Not only do they teach children how to read and write butteachers are also charged with the task of creating responsible citizens who should think critically about society. Teacher educators, and specifically those individuals charged with the task of preparing preservice teachers, have responsibilities similar to teachers in the field. Education, on any level, ought to be a transformative process.
Thus, the preparation of teachers as instruments of social change ought to be a central focus in preservice teacher education programs. Teacher educators, as well as elementary and secondary mentor school teachers, are agents who have the potential to guide preservice teachers to think critically about educational structures that either promote or hinder the development of social equality in schools. Our views are corroborated by scholars such as Gloria Ladson-Billings who states that teacher education programs throughout the nation have coupled their efforts at reform with revised programs committed to social justice and equity (1995, p. 466)
Safety and efficacy of intravenous iron therapy in reducing requirement for allogeneic blood transfusion: systematic review and meta-analysis of randomised clinical trials
Objectives To evaluate the efficacy and safety of intravenous iron, focusing primarily on its effects on haemoglobin, requirement for transfusion, and risk of infection. Design Systematic review and meta-analysis of randomised controlled trials investigating the safety and efficacy of intravenous iron therapy. Data sources Randomised controlled trials from Medline, Embase, and the Cochrane Central Register of Controlled Trials from 1966 to June 2013, with no language restrictions. Eligibility criteria for selecting studies Eligible trials were randomised controlled trials of intravenous iron compared with either no iron or oral iron. Crossover and observational studies were excluded. Main outcome measures Change in haemoglobin concentration and risk of allogeneic red blood cell transfusion (efficacy) and risk of infection (safety). Results Of the 75 trials meeting the inclusion criteria, 72 studies including 10 605 patients provided quantitative outcome data for meta-analysis. Intravenous iron was associated with an increase in haemoglobin concentration (standardised mean difference 6.5 g/L, 95% confidence interval 5.1 g/L to 7.9 g/L) and a reduced risk of requirement for red blood cell transfusion (risk ratio 0.74, 95% confidence interval 0.62 to 0.88), especially when intravenous iron was used with erythroid stimulating agents (ESAs) or in patients with a lower baseline plasma ferritin concentration. There were no significant interactions between the efficacy of intravenous iron and type or dose administered. Intravenous iron was, however, associated with a significant increase in risk of infection (relative risk 1.33, 95% confidence interval 1.10 to 1.64) compared with oral or no iron supplementation. The results remained similar when only high quality trials were analysed. Conclusions Intravenous iron therapy is effective in increasing haemoglobin concentration and reducing the risk of allogeneic red blood cell transfusion and could have broad applicability to a range of acute care settings. This potential benefit is counterbalanced by a potential increased risk of infection
Molecular methodologies for improved polymicrobial sepsis diagnosis
Polymicrobial sepsis is associated with worse patient outcomes than monomicrobial sepsis. Routinely used culture-dependent microbiological diagnostic techniques have low sensitivity, often leading to missed identification of all causative organisms. To overcome these limitations, culture-independent methods incorporating advanced molecular technologies have recently been explored. However, contamination, assay inhibition and interference from host DNA are issues that must be addressed before these methods can be relied on for routine clinical use. While the host component of the complex sepsis host–pathogen interplay is well described, less is known about the pathogen’s role, including pathogen–pathogen interactions in polymicrobial sepsis. This review highlights the clinical significance of polymicrobial sepsis and addresses how promising alternative molecular microbiology methods can be improved to detect polymicrobial infections. It also discusses how the application of shotgun metagenomics can be used to uncover pathogen/pathogen interactions in polymicrobial sepsis cases and their potential role in the clinical course of this condition
\u3ci\u3eFamilies, Crime and Criminal Justice: Charting the Linkages\u3c/i\u3e
Contemporary Perspectives in Family Research is a series of volumes that features scholarly work on the frontiers of interdisciplinary research on families and family life. Volume 2, Families, Crime and Criminal Justice reflects this pioneering orientation by bringing together new empirical research that examines the various ways that families intersect with and are affected by crime and the criminal justice system. The interdisciplinary nature of the volume is reflected in the diversity of disciplines represented, including developmental psychopathology, criminology, sociology, family studies, psychology, social work and demography. The inclusion of qualitative studies based upon observational techniques and in-depth, long interviews as well as quantitative work using demographic and survey approaches demonstrates the wide methodological range employed by the authors. The topics examined include the involvement of children in crime, the patterns and impact of violence in the home, the impact of criminal involvement on parenting strategies and youth development, the experience of families of victims and perpetrators, and responses of the criminal justice system to the needs of families
\u3ci\u3eFamilies, Crime and Criminal Justice: Charting the Linkages\u3c/i\u3e
Chapter: Gender Differences in the Effect of Child Maltreatment on Criminal Activity over the Life Course, written by Ryan Spohn, UNO faculty member.
Contemporary Perspectives in Family Research is a series of volumes that features scholarly work on the frontiers of interdisciplinary research on families and family life. Volume 2, Families, Crime and Criminal Justice reflects this pioneering orientation by bringing together new empirical research that examines the various ways that families intersect with and are affected by crime and the criminal justice system. The interdisciplinary nature of the volume is reflected in the diversity of disciplines represented, including developmental psychopathology, criminology, sociology, family studies, psychology, social work and demography. The inclusion of qualitative studies based upon observational techniques and in-depth, long interviews as well as quantitative work using demographic and survey approaches demonstrates the wide methodological range employed by the authors. The topics examined include the involvement of children in crime, the patterns and impact of violence in the home, the impact of criminal involvement on parenting strategies and youth development, the experience of families of victims and perpetrators, and responses of the criminal justice system to the needs of families.https://digitalcommons.unomaha.edu/facultybooks/1161/thumbnail.jp
Accelerated soil carbon loss does not explain warming related increases in soil CO2 efflux
The universally observed exponential increase in soil-surface CO2 efflux (‘soil respiration’; FS) with increasing temperature has led to speculation that global warming will accelerate soil-organic-carbon (SOC) decomposition, reduce SOC storage, and drive a positive feedback to future warming. However, interpreting temperature–FS relationships, and so modelling terrestrial carbon balance in a warmer world, is complicated by the many sources of respired carbon that contribute to FS (ref. 3) and a poor understanding of how temperature influences SOC decomposition rates. Here we quantified FS, litterfall, bulk SOC and SOC fraction size and turnover, and total below-ground carbon flux (TBCF) across a highly constrained 5.2 °C mean annual temperature (MAT) gradient in tropical montane wet forest. From these, we determined that: increases in TBCF and litterfall explain >90% of the increase in FS with MAT; bulk SOC and SOC fraction size and turnover rate do not vary with MAT; and increases in TBCF and litterfall do not influence SOC storage or turnover on century to millennial timescales. This gradient study shows that for tropical montane wet forest, long-term and whole-ecosystem warming accelerates below-ground carbon processes with no apparent impact on SOC storage
A randomised controlled trial of succinylated gelatin (4%) fluid on urinary acute kidney injury biomarkers in cardiac surgical patients
Background
Fluid resuscitation is frequently required for cardiac surgical patients admitted to the intensive care unit. The ideal fluid of choice in regard to efficacy and safety remains uncertain. Compared with crystalloid fluid, colloid fluid may result in less positive fluid balance. However, some synthetic colloids are associated with increased risk of acute kidney injury (AKI). This study compared the effects of succinylated gelatin (4%) (GEL) with compound sodium lactate (CSL) on urinary AKI biomarkers in patients after cardiac surgery.
Methods
Cardiac surgical patients who required an intravenous fluid bolus of at least 500 mL postoperatively were randomly allocated to receive GEL or CSL as the resuscitation fluid of choice for the subsequent 24 h. Primary outcomes were serial urinary neutrophil gelatinase-associated lipocalin (NGAL) and cystatin C concentrations measured at baseline, 1 h, 5 h and 24 h after enrolment, with higher concentrations indicating greater kidney injury. Secondary biomarker outcomes included urinary clusterin, α1-microglobulin and F2-isoprostanes concentrations. Differences in change of biomarker concentration between the two groups over time were compared with mixed-effects regression models. Statistical significance was set at P < 0.05.
Results
Forty cardiac surgical patients (n = 20 per group) with similar baseline characteristics were included. There was no significant difference in the median volume of fluid boluses administered over 24 h between the GEL (1250 mL, Q1–Q3 500–1750) and CSL group (1000 mL, Q1–Q3 500–1375) (P = 0.42). There was a significantly greater increase in urinary cystatin C (P < 0.001), clusterin (P < 0.001), α1-microglobulin (P < 0.001) and F2-isoprostanes (P = 0.020) concentrations over time in the GEL group, compared to the CSL group. Change in urinary NGAL concentration (P = 0.68) over time was not significantly different between the groups. The results were not modified by adjustment for either urinary osmolality or EuroSCORE II predicted risk of mortality.
Conclusions
This preliminary randomised controlled trial showed that use of succinylated gelatin (4%) for fluid resuscitation after cardiac surgery was associated with increased biomarker concentrations of renal tubular injury and dysfunction, compared to crystalloid fluid. These results generate concern that use of intravenous gelatin fluid may contribute to clinically relevant postoperative AKI
Relativistic suppression of Auger recombination in Weyl semimetals
Auger recombination (AR) being electron-hole annihilation with
energy-momentum transfer to another carrier is believed to speed up in
materials with small band gap. We theoretically show that this rule is violated
in gapless three-dimensional materials with ultra-relativistic electron-hole
dispersion, Weyl semimetals (WSM). Namely, AR is prohibited by energy-momentum
conservation laws in prototypical WSM with a single Weyl node, even in the
presence of anisotropy and tilt. In real multi-node WSM, the geometric
dissimilarity of nodal dispersions enables weak inter-node AR, which is further
suppressed by strong screening due to large number of nodes. While partial AR
rates between the nodes of the same node group are mutually equal, the
inter-group processes are non-reciprocal, so that one of groups is
geometrically protected from AR. Our calculations show that geometrical
protection can help prolonging AR lifetime by the two orders of magnitude, up
to the level of nanoseconds.Comment: 6 pages + 10 pages of supporting informatio
An experimental model to measure the ability of headphones with active noise control to reduce patient's exposure to noise in an intensive care unit.
BACKGROUND: Defining the association between excessive noise in intensive care units, sleep disturbance and morbidity, including delirium, is confounded by the difficulty of implementing successful strategies to reduce patient's exposure to noise. Active noise control devices may prove to be useful adjuncts but there is currently little to quantify their ability to reduce noise in this complex environment. METHODS: Sound meters were embedded in the auditory meatus of three polystyrene model heads with no headphones (control), with headphones alone and with headphones using active noise control and placed in patient bays in a cardiac ICU. Ten days of recording sound levels at a frequency of 1 Hz were performed, and the noise levels in each group were compared using repeated measures MANOVA and subsequent pairwise testing. RESULTS: Multivariate testing demonstrated that there is a significant difference in the mean noise exposure levels between the three groups (p < 0.001). Subsequent pairwise testing between the three groups shows that the reduction in noise is greatest with headphones and active noise control. The mean reduction in noise exposure between the control and this group over 24 h is 6.8 (0.66) dB. The use of active noise control was also associated with a reduction in the exposure to high-intensity sound events over the course of the day. CONCLUSIONS: The use of active noise cancellation, as delivered by noise-cancelling headphones, is associated with a significant reduction in noise exposure in our model of noise exposure in a cardiac ICU. This is the first study to look at the potential effectiveness of active noise control in adult patients in an intensive care environment and shows that active noise control is a candidate technology to reduce noise exposure levels the patients experience during stays on intensive care
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