562 research outputs found

    Performance analysis of wireless LANs: an integrated packet/flow level approach

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    In this paper we present an integrated packet/flow level modelling approach for analysing flow throughputs and transfer times in IEEE 802.11 WLANs. The packet level model captures the statistical characteristics of the transmission of individual packets at the MAC layer, while the flow level model takes into account the system dynamics due to the initiation and completion of data flow transfers. The latter model is a processor sharing type of queueing model reflecting the IEEE 802.11 MAC design principle of distributing the transmission capacity fairly among the active flows. The resulting integrated packet/flow level model is analytically tractable and yields a simple approximation for the throughput and flow transfer time. Extensive simulations show that the approximation is very accurate for a wide range of parameter settings. In addition, the simulation study confirms the attractive property following from our approximation that the expected flow transfer delay is insensitive to the flow size distribution (apart from its mean)

    Potential beneficial effects of cytomegalovirus infection after transplantation

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    Cytomegalovirus (CMV) infection can cause significant complications after transplantation, but recent emerging data suggest that CMV may paradoxically also exert beneficial effects in two specific allogeneic transplant settings. These potential benefits have been underappreciated and are therefore highlighted in this review. First, after allogeneic hematopoietic stem cell transplantation (HSCT) for acute myeloid leukemia (AML) using T-cell and natural killer (NK) cell-replete grafts, CMV reactivation is associated with protection from leukemic relapse. This association was not observed for other hematologic malignancies. This anti-leukemic effect might be mediated by CMV-driven expansion of donor-derived memory-like NKG2C+ NK and Vδ2negγδ T-cells. Donor-derived NK cells probably recognize recipient leukemic blasts by engagement of NKG2C with HLA-E and/or by the lack of donor (self) HLA molecules. Vδ2negγδ T cells probably recognize as yet unidentified antigens on leukemic blasts via their TCR. Second, immunological imprints of CMV infection, such as expanded numbers of Vδ2negγδ T cells and terminally differentiated TCRαβ+ T cells, as well as enhanced NKG2C gene expression in peripheral blood of operationally tolerant liver transplant patients, suggest that CMV infection or reactivation may be associated with liver graft acceptance. Mechanistically, poor alloreactivity of CMV-induced terminally differentiated TCRαβ+ T cells and CMV-induced IFN-driven adaptive immune resistance mechanisms in liver grafts may be involved. In conclusion, direct associations indicate that CMV reactivation may protect against AML relapse after allogeneic HSCT, and indirect associations suggest that CMV infection may promote allograft acceptance after liver transplantation. The causative mechanisms need further investigations, but are probably related to the profound and sustained imprint of CMV infection on the immune system

    Application-level performance of cross-layer scheduling for social VR in 5G

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    Social VR aims at enabling people located at different places to communicate and interact with each other in a natural way. It poses extremely strong throughput and latency requirements on the underlying communication networks. This paper investigates the potential of using cross-layer design approaches for radio access scheduling in order to realize these challenging requirements in (beyond) 5G networks. In particular, we provide an in-depth simulation study of the performance/capacity gains that can be achieved by exploiting the end-to-end latency budget and/or video frame type as cross-layer information in the scheduling decisions, and show how the benefits depend on the actual social VR scenario. This study further reveals the importance of using application-level metrics such as PSNR or SSIM rather than traditional network-level metrics like the packet drop rate in the performance assessment.</p

    Decomposing the queue length distribution of processor-sharing models into queue lengths of permanent customer queues

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    We obtain a decomposition result for the steady state queue length distribution in egalitarian processor-sharing (PS) models. In particular, for an egalitarian PS queue with KK customer classes, we show that the marginal queue length distribution for class kk factorizes over the number of other customer types. The factorizing coefficients equal the queue length probabilities of a PS queue for type kk in isolation, in which the customers of the other types reside \textit{ permanently} in the system. Similarly, the (conditional) mean sojourn time for class kk can be obtained by conditioning on the number of permanent customers of the other types. The decomposition result implies linear relations between the marginal queue length probabilities, which also hold for other PS models such as the egalitarian processor-sharing models with state-dependent system capacity that only depends on the total number of customers in the system. Based on the exact decomposition result for egalitarian PS queues, we propose a similar decomposition for discriminatory processor-sharing (DPS) models, and numerically show that the approximation is accurate for moderate differences in service weights. \u

    Learning Optimal Deep Projection of 18^{18}F-FDG PET Imaging for Early Differential Diagnosis of Parkinsonian Syndromes

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    Several diseases of parkinsonian syndromes present similar symptoms at early stage and no objective widely used diagnostic methods have been approved until now. Positron emission tomography (PET) with 18^{18}F-FDG was shown to be able to assess early neuronal dysfunction of synucleinopathies and tauopathies. Tensor factorization (TF) based approaches have been applied to identify characteristic metabolic patterns for differential diagnosis. However, these conventional dimension-reduction strategies assume linear or multi-linear relationships inside data, and are therefore insufficient to distinguish nonlinear metabolic differences between various parkinsonian syndromes. In this paper, we propose a Deep Projection Neural Network (DPNN) to identify characteristic metabolic pattern for early differential diagnosis of parkinsonian syndromes. We draw our inspiration from the existing TF methods. The network consists of a (i) compression part: which uses a deep network to learn optimal 2D projections of 3D scans, and a (ii) classification part: which maps the 2D projections to labels. The compression part can be pre-trained using surplus unlabelled datasets. Also, as the classification part operates on these 2D projections, it can be trained end-to-end effectively with limited labelled data, in contrast to 3D approaches. We show that DPNN is more effective in comparison to existing state-of-the-art and plausible baselines.Comment: 8 pages, 3 figures, conference, MICCAI DLMIA, 201
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