INSTITUTIONAL AFFILIATION OF AUTHORS IN THE AMERICAN JOURNAL OF AGRICULTURAL ECONOMICS, 1988-1992

Opaluch and Just reported the top 20 departments in pages per faculty of articles in the American Journal of Agricultural Economics for the five year period 1968-1972. To determine how much has changed and how much has not during the intervening two decades, the analysis was repeated for the five year period 1988-1992. Some things seem not to change. University of California, Berkeley, remains at the pinnacle twenty years later. And 13 of the top 20 departments two decades ago, remain there during the 1988-1992 period. But seven did change, and the most notable aspect is that the number of Northeast departments in the top 20 rose from two to five.Teaching/Communication/Extension/Profession,

Faculty Outreach with Student Workers

Seton Hall University’s Institutional Repository (scholarship.shu.edu) is a publishing service offered by the Seton Hall University Libraries and Seton Hall Law School for preservation and dissemination of SHU scholarly works. The Faculty Profiles, electronic journals, electronic theses and dissertations (ETDs) provide the majority of the content. There are almost 10,000 papers and 2.4 million downloads. Seton Hall University Libraries implemented Selected Works in 2010. Currently liaison librarians use Selected Works as a communication vehicle with faculty members to create profiles, post scholarship based on Sherpa Romeo copyright rules and tracking readership worldwide. In 2017-8, two student workers helped to check copyright, create profiles, post content and conduct outreach to faculty. Due to their help we were able to almost double the amount of profiles and maintain existing ones. This presentation will describe the workflow for adding profiles and content and best practices for collaborating with a student team. Other collections students have helped add to the repository include Digital Humanities Projects and Open Education Resources. This helps to add exposure to University Committees and Resources

The proximal first exon architecture of the murine ghrelin gene is highly similar to its human orthologue

BACKGROUND: The murine ghrelin gene (Ghrl), originally sequenced from stomach tissue, contains five exons and a single transcription start site in a short, 19 bp first exon (exon 0). We recently isolated several novel first exons of the human ghrelin gene and found evidence of a complex transcriptional repertoire. In this report, we examined the 5' exons of the murine ghrelin orthologue in a range of tissues using 5' RACE. -----FINDINGS: 5' RACE revealed two transcription start sites (TSSs) in exon 0 and four TSSs in intron 0, which correspond to 5' extensions of exon 1. Using quantitative, real-time RT-PCR (qRT-PCR), we demonstrated that extended exon 1 containing Ghrl transcripts are largely confined to the spleen, adrenal gland, stomach, and skin. -----CONCLUSION: We demonstrate that multiple transcription start sites are present in exon 0 and an extended exon 1 of the murine ghrelin gene, similar to the proximal first exon organisation of its human orthologue. The identification of several transcription start sites in intron 0 of mouse ghrelin (resulting in an extension of exon 1) raises the possibility that developmental-, cell- and tissue-specific Ghrl mRNA species are created by employing alternative promoters and further studies of the murine ghrelin gene are warranted

Complex organisation and structure of the ghrelin antisense strand gene GHRLOS, a candidate non-coding RNA gene

<p>Abstract</p> <p>Background</p> <p>The peptide hormone ghrelin has many important physiological and pathophysiological roles, including the stimulation of growth hormone (GH) release, appetite regulation, gut motility and proliferation of cancer cells. We previously identified a gene on the opposite strand of the ghrelin gene, ghrelinOS (<it>GHRLOS</it>), which spans the promoter and untranslated regions of the ghrelin gene (<it>GHRL</it>). Here we further characterise <it>GHRLOS</it>.</p> <p>Results</p> <p>We have described <it>GHRLOS </it>mRNA isoforms that extend over 1.4 kb of the promoter region and 106 nucleotides of exon 4 of the ghrelin gene, <it>GHRL</it>. These <it>GHRLOS </it>transcripts initiate 4.8 kb downstream of the terminal exon 4 of <it>GHRL </it>and are present in the 3' untranslated exon of the adjacent gene <it>TATDN2 </it>(TatD DNase domain containing 2). Interestingly, we have also identified a putative non-coding <it>TATDN2-GHRLOS </it>chimaeric transcript, indicating that <it>GHRLOS </it>RNA biogenesis is extremely complex. Moreover, we have discovered that the 3' region of <it>GHRLOS </it>is also antisense, in a tail-to-tail fashion to a novel terminal exon of the neighbouring <it>SEC13 </it>gene, which is important in protein transport. Sequence analyses revealed that <it>GHRLOS </it>is riddled with stop codons, and that there is little nucleotide and amino-acid sequence conservation of the <it>GHRLOS </it>gene between vertebrates. The gene spans 44 kb on 3p25.3, is extensively spliced and harbours multiple variable exons. We have also investigated the expression of <it>GHRLOS </it>and found evidence of differential tissue expression. It is highly expressed in tissues which are emerging as major sites of non-coding RNA expression (the thymus, brain, and testis), as well as in the ovary and uterus. In contrast, very low levels were found in the stomach where sense, <it>GHRL </it>derived RNAs are highly expressed.</p> <p>Conclusion</p> <p><it>GHRLOS </it>RNA transcripts display several distinctive features of non-coding (ncRNA) genes, including 5' capping, polyadenylation, extensive splicing and short open reading frames. The gene is also non-conserved, with differential and tissue-restricted expression. The overlapping genomic arrangement of <it>GHRLOS </it>with the ghrelin gene indicates that it is likely to have interesting regulatory and functional roles in the ghrelin axis.</p

Forest Change in the Driftless Area of the Midwest: From a Preferred to Undesirable Future

In the midwestern and eastern U.S., oaks (Quercus spp.) have been a dominant component of forests for at least the last 10,000 years, providing vital habitat for numerous wildlife and plant species that have adapted to oak forest conditions. However, the current state of these oak systems, in which there has been a general lack of successful oak regeneration and recruitment and an increase in the relative dominance of mesophytic species, may be nearing critical thresholds. If reached, restoring oak systems through natural regeneration and other methods, such as prescribed fire, may become especially challenging if not impossible. An understanding of spatial variation in oak dominance over time can inform and potentially improve the efficacy of intervention strategies. Using Public Land Survey and Forest Inventory and Analysis (FIA) inventories, we evaluated changes in the composition of timberland across ecoregional subsections in the Driftless Area of the Midwest at three time periods (pre-settlement 1800s, 1990s, and 2000s). We identified an overall decrease in oak dominance, and particularly dominance of the white oak (Quercus alba L., Q. macrocarpa Michx., and Q. bicolor Willd.) species group since the presettlement era, and an increase in other eastern soft hardwoods. Within the last 20 years, both the red oak (Q. rubra L., Q. ellipsoidalis E.J. Hill and Q. velutina Lam.) and white oak species groups decreased in dominance, with an increase in hard maple-basswood (A. saccharum Marsh., A. nigra L., and Tilia americana L.) species group dominance, indicating further mesophication of forests in the region. However, we found a notable decrease in hard maple-basswood relative dominance within the small diameter class across most of the regions within the last 10–20 years, with an increase in dominance of other, non-oak, species. Our findings complement qualitative evidence from interviews with natural resource professionals from the region and offer further information on the potential for forest conversion to ‘‘undesirable’’ forest conditions, as identified as a source of concern by some professionals. There was spatial variation in these trends, however, with some pronounced differences across adjacent state boundaries. The variation in forest change across state boundaries suggests the role of state-level socioeconomic and policy factors in affecting forest conditions, and thus the potential for a targeted and timely approach to promoting preferred pathways of change

Solution-processed nickel tetrabenzoporphyrin thin-film transistors

We describe nickel tetrabenzoporphyrin (NiTBP) as a solution-processible organic semiconductor. Whereas porphyrins in an unmodified state are typically planar and insoluble, a precursor synthetic route (NiCP) was used to deposit thin films via solution. Amorphous, insulating thin films of NiCP were deposited, and thermally converted to polycrystalline, semiconducting NiTBP. Films were studied using optical absorption and microscopy, atomic force microscopy, and x-ray diffraction. Highly concentrated NiCP was shown to form large, needle-shaped crystals drop-cast from solution. NiTBP thin-film field-effect transistors fabricated from spun-cast films demonstrated charge-carrier field-effect mobilities on the order of 0.1 and 0.2 cm2/V s0.2cm2∕Vs and accumulation threshold voltages of −19−19 and −13−13, in the linear and saturation regimes, respectively.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/87777/2/034502_1.pd

“Where I am weak, they are strong”: Students’ Perceptions and Attitudes Toward Interprofessional Education

Purpose: Healthcare professionals strive for interprofessional practice to achieve optimal patient care. Extant research suggests that to best prepare students for interprofessional practice, interprofessional education (IPE) should be a key element in curriculum. The purpose of this mixed-methods study was to evaluate the impact of an IPE activity on participants’ attitudes and perceptions of IPE across five academic programs. Methods: This study utilized a modified version of the Readiness for Interprofessional Learning Scale Questionnaire (RIPLS) pre and post IPE and reflective essays. Participants included 67 students from nursing, occupational therapy, athletic training, dietetics, and speech-language pathology programs. After reviewing a hypothetical case study, participants collaboratively developed assessment and treatment recommendations. Questionnaires were analyzed using statistical procedures and reflective essays underwent thematic analysis. Results: Collectively, data revealed significant changes in participants’ perceptions, attitudes, and implementation readiness. Occupational therapy student participants had statistically significant increases in the RIPLS composite score, Teamwork and Collaboration, and the Positive Professional Identity components (p≤0.03). Participants with previous IPE experience scored 4-points higher on the RIPLS composite score (p=0.03). The reflective essays revealed the themes of barriers associated with collaboration, a deeper understanding and appreciation of other discipline’s roles and the value of teamwork in achieving optimal patient care. Participants reported beginning the interprofessional education experience with anxiety and uncertainty about not only their involvement but also the roles of other healthcare professionals. Throughout the experience, participants emerged with an increased knowledge of their role, others’ roles, and the value of working together within a professional setting to achieve the same goal, optimal patient care. Conclusions: Our findings reveal the benefits of interprofessional education and the necessity to include several healthcare professionals associated with rehabilitation in interprofessional research and education. With more disciplines represented, students receive a broader, more in-depth understanding of not only patient care but also the roles of multiple disciplines they will collaborate with during actual rehabilitative practice

Racial differences in cumulative disadvantage among women and its relation to health: Development and preliminary validation of the CSI-WE

Background: Cumulative disadvantage (CD) is a measure of accumulated social, economic, and person-related stressors due to unequal access to resources and opportunities, which increases a person's biological risk for disease. The purpose of this research was to develop an instrument tailored to women's experiences that had intervention and translational potential. In addition, we explored whether CD contributed to racial health disparities among black and white women. Methods: In-depth life course interviews were used to assess stressful experiences of 15 black and 15 white women. Using information from the interviews, we developed the Cumulative Stress Inventory of Women's Experiences (CSI-WE) as a quantitative instrument to measure stressful life experiences from childhood to adulthood. The CSI-WE was then administered to the original 30 women for validation and feedback. Results: Qualitative and quantitative assessments were highly correlated, which suggested that the CSI-WE reliably captured the experiences of the interviewed women. Black participants reported significantly higher numbers of childhood and adult stressors, more acute adulthood and lifetime stressors, and worse adult physical self-rated health. Conclusions: This study supports the preliminary validity of an instrument that once fully validated may be used in future studies to elucidate the experiences of CD among black and white women and examines how these experiences relate to perceived and objective health status

Poly(Limonene Thioether) Scaffold for Tissue Engineering

A photocurable thiol-ene network polymer, poly(limonene thioether) (PLT32o), is synthesized, characterized, fabricated into tissue engineering scaffolds, and demonstrated in vitro and in vivo. Micromolded PLT32o grids exhibit compliant, elastomeric mechanical behavior similar to grids made of poly(glycerol sebacate) (PGS), an established biomaterial. Multilayered PL32o scaffolds with regular, geometrically defined pore architectures support heart cell seeding and culture in a manner similar to multilayered PGS scaffolds. Subcutaneous implantation of multilayered PLT32o scaffolds with cultured heart cells provides long-term 3D structural support and retains the exogenous cells, whereas PGS scaffolds lose both their structural integrity and the exogenous cells over 31 d in vivo. PLT32o membrane implants retain their dry mass, whereas PGS implants lose 70 percent of their dry mass by day 31. Macrophages are initially recruited to PLT32o and PGS membrane implants but are no longer present by day 31. Facile synthesis and processing in combination with the capability to support heart cells in vitro and in vivo suggest that PLT32o can offer advantages for tissue engineering applications where prolonged in vivo maintenance of 3D structural integrity and elastomeric mechanical behavior are required.United States. National Institutes of Health (R01-HL107503