205 research outputs found
Protection of Centriole Engagement in Mitosis by Alternatively Spliced Shugoshin1 Isoforms in Complex with Protein Phosphatase 2A
Cultivating an Online Network for Mentoring Preservice and In-Service Teachers
This report details the work of two initial teacher certification programs at a major university in Kentucky that are implementing two innovative strategies for preservice teachers to network, build community, and grow in their practice. The utilization of Slack, a free online communication platform, has proven successful in getting preservice teachers to share ideas, pose and respond to professional questions, and program information dissemination. The use of a NIC (Networked Improvement Community) is a grant funded endeavor that brought together preservice teachers, their cooperating teachers, and university faculty members to create a professional learning community where a problem of practice was identified and PDSA (plan, do, study, act) cycles were utilized to improve classroom practices
The effects of dyad reading and text difficulty on third-graders’ reading achievement
This study replicated, with modifications, previous research of dyad reading using texts at various levels of difficulty (Morgan, 1997). The current project measured the effects of using above–grade-level texts on reading achievement and sought to determine the influences of dyad reading on both lead and assisted readers. Results indicate that weaker readers, using texts at two, three, and four grade levels above their instructional levels with the assistance of lead readers, outscored both proficient and less proficient students in the control group across multiple measures of reading achievement. However, the gains made by assisted readers were not significantly different relative to the various text levels. When all assessments were considered, assisted readers reading texts two grade levels above their instructional levels showed the most robust gains in oral reading fluency and comprehension. Lead readers also benefited from dyad reading and continued their respective reading developmental trajectories across measures
Messung von Ressourceneffizienz mit der ESSENZ-Methode
Eine belastbare Methode zu entwickeln, um den Ressourceneinsatz zu bewerten, ist das Ziel dieses Buches. Notwendig ist dies, da das starke Wirtschaftswachstum der letzten Jahrzehnte zu einer intensiven Beanspruchung natürlicher Ressourcen geführt hat. Mit ihrer steigenden Nutzung gehen auch zusätzliche Belastungen der Umwelt sowie Restriktionen der Verfügbarkeit von Ressourcen einher. Aus diesen Gründen ist ein effizienter Einsatz von Ressourcen als wichtiger Beitrag zu einer nachhaltigen Entwicklung erforderlich.
Die ESSENZ-Methode (Integrierte Methode zur ganzheitlichen Berechnung/Messung von Ressourceneffizienz) wurde in einer Kooperation der Technischen Universität Berlin mit den Industriepartnern Daimler AG, Deutsches Kupferinstitut Berufsverband e. V., Evonik Industries AG, Siemens AG, ThyssenKrupp Steel Europe AG und Wissenschaftlicher Gerätebau Dr. Ing. Herbert Knauer GmbH entwickelt. Sie unterstützt die umfassende Messung und Bewertung von Ressourceneffizienz innerhalb der vier Dimensionen „Verfügbarkeit“, „Gesellschaftliche Akzeptanz“, „Umweltauswirkungen“ und „Nutzen“. Um diese vier Dimensionen wissenschaftlich abzubilden, werden 21 anwendbare Indikatoren entwickelt und vorgestellt.
Die ESSENZ-Methode kann sowohl fĂĽr die Analyse und Optimierung eines einzelnen Produktes als auch fĂĽr den Vergleich mehrerer Produktalternativen verwendet werden. Ihre Anwendbarkeit ist fĂĽr Metalle und fossile Rohstoffe bereits erprobt.BMBF, 033R094A-F, rÂł - Strategische Metalle, Verbundvorhaben: Integrierte Methode zur ganzheitlichen Berechnung/Messung von Ressourceneffizienz - ESSEN
Integrated method to assess resource efficiency – ESSENZ
With increasing demand of abiotic resources also the pollution of natural resources like water and soil has risen in the last decades due to global industrial and technological development. Thus, enhancing resource efficiency is a key goal of national and international strategies. For a comprehensive assessment of all related impacts of resource extraction and use all three sustainability dimensions have to be taken into account: economic, environmental and social aspects. Furthermore, to avoid burden shifting life cycle based methods should be applied. As companies need operational tools and approaches, a comprehensive method has been developed to measure resource efficiency of products, processes and services in the context of sustainable development (ESSENZ). Overall 21 categories are established to measure impacts on the environment, physical and socio-economic availability of the used resources as well as their societal acceptance. For the categories socio-economic availability and societal acceptance new approaches are developed and characterization factors are provided for a portfolio of 36 metals and four fossil raw materials. The introduced approach has been tested on several case studies, demonstrating that it enhances the applicability of resource efficiency to assess product systems significantly by providing an overall framework that can be adopted across sectors, using indicators and methods which are applicable and can be integrated into existing life cycle assessment based schemes.BMBF, 033R094A-F, rÂł - Strategische Metalle, Verbundvorhaben: Integrierte Methode zur ganzheitlichen Berechnung/Messung von Ressourceneffizienz - ESSEN
The Grizzly, March 6, 2003
Preparing for the Future Today: Job and Internship Fair 2003 • The Art of Kissing • Trading the Beach for Hard Work • Celebrating Women\u27s History Month with Ursinus Legends • Showcasing Women\u27s Pride in Berman • Bloody Poetry Director Speaks Out • Women\u27s History Month Events • Centennial Conference Champions! • UC Swimmers Make a Splash • Ykoruk Named Women\u27s Head Soccer Coachhttps://digitalcommons.ursinus.edu/grizzlynews/1531/thumbnail.jp
Donepezil alone and combined with intensive language-action therapy on depression and apathy in chronic post-stroke aphasia: A feasibility study
This study explored the feasibility and effectiveness of a short-term (10-week) intervention trial using Donepezil administered alone and combined with intensive language action therapy (ILAT) for the treatment of apathy and depression in ten people with chronic post-stroke aphasia. Outcome measures were the Western Aphasia Battery and the Stroke Aphasia Depression Questionnaire-21. Structural magnetic resonance imaging and 18fluorodeoxyglucose positron emission tomography were acquired at baseline and after two endpoints (Donepezil alone and Donepezil-ILAT). The intervention was found to be feasible to implement. Large treatment effects were found. Donepezil alone and combined with ILAT reduced aphasia severity, while apathy and depression only improved with Donepezil-ILAT. Structural and functional neuroimaging data did not show conclusive results but provide hints for future research. Given these overall positive findings on feasibility, language and behavioral benefits, further studies in larger sample sizes and including a placebo-control group are indicated
Donepezil alone and combined with intensive language-action therapy on depression and apathy in chronic post-stroke aphasia: A feasibility study
This study explored the feasibility and effectiveness of a short-term (10-week) intervention trial using Donepezil administered alone and combined with intensive language action therapy (ILAT) for the treatment of apathy and depression in ten people with chronic post-stroke aphasia. Outcome measures were the Western Aphasia Battery and the Stroke Aphasia Depression Questionnaire-21. Structural magnetic resonance imaging and 18fluorodeoxyglucose positron emission tomography were acquired at baseline and after two endpoints (Donepezil alone and Donepezil-ILAT). The intervention was found to be feasible to implement. Large treatment effects were found. Donepezil alone and combined with ILAT reduced aphasia severity, while apathy and depression only improved with Donepezil-ILAT. Structural and functional neuroimaging data did not show conclusive results but provide hints for future research. Given these overall positive findings on feasibility, language and behavioral benefits, further studies in larger sample sizes and including a placebo-control group are indicated.This work was supported as an independent research grant funded by Pfizer and Eisai. The funders were not involved in the study design, collection, analysis, or interpretation of the data. The work was also supported in part by the Ministerio de EconomĂa, Industria y Competitividad, Instituto de Salud Carlos III, Spain (under Grant: PI16/01514; MLB and GD), and the Junta de AndalucĂa, Spain (under Grant: P20_00501; GD). MLB has been supported by funds from the European Social Fund (FEDER). LE and FJL-G have been funded by a PhD scholarship from the Spanish Ministry of Education, Culture, and Sport under the FPU program (FPU17/04136; FJL-G: FPU17/04470). DL-B was supported by I + D + i Project Andalusia and European Union Funds (FEDER) (UMA18-FEDERJA-221) and by RamĂłn y Cajal Program (RYC2020-029495-I) from the Spanish Ministry of Science and Innovation. MT-P has been funded by a postdoctoral fellowship under the program Plan Andaluz de InvestigaciĂłn, Desarrollo e InnovaciĂłn (PAIDI 2020) (DOC_00421). FP and BM were supported by the Deutsche Forschungsgemeinschaft [Pu 97/15-1 and 15-2 to FP, Mo 697/5-2 to BM]. FP was also supported by the European Research Council [ERC-2019-ADG 883811] // Funding for open access charge: Universidad de Málaga / CBUA
Neural signatures of treatment-induced benefits in apathy and depression amongst persons with aphasia
Intensive language-action therapy (ILAT) reduces symptoms of depression in persons with aphasia (PWA) due to stroke. The neural correlates of such improvement remain unexplored. Here we evaluated apathy and depression in PWA receiving treatment with the cholinesterase inhibitor donepezil (DP) alone and combined with ILAT as well as the brain changes promoted by these interventions. Ten PWA with chronic left perisylvian strokes participated in a 10-week open-label pilot study. They received DP alone (wk 0-8) and thereafter combined with ILAT (wk 8-10 30 hours, wks 8-10). Structural MRI and resting state [18]fluorodeoxyglucose PET (18FDG-PET) were acquired for at 3 time-points in order to measure grey matter density (Voxel-based morphometry, VBM) and metabolic changes. The primary outcome measures were: Aphasia Quotient of the Western Aphasia Battery (AQ-WAB), Communicative Activity Log (CAL), Stroke Aphasic Depression Questionnaire (SADQ), and Stroke and Aphasia Quality of Life Scale-39 (SAQoL-39). The 21-item SADQ was used to examine apathy (7 items) and depression (14 items). Significant improvements with DP alone and under DP-ILAT were seen in AQ-WAB, CAL and SAQoL-39. Improvements in symptoms of apathy and depression were observed when comparing DP-ILAT with baseline. 18FDG-PET analysis revealed that DP alone induced significant increments in metabolic activity in cortical and subcortical areas that correlated with improvement in apathetic and depressive symptoms. VBM analyses revealed that DP alone and combined DP-ILAT induced increases in grey matter density in areas of the right hemisphere previously associated to improvements in apathy and depression. In conclusion, treatment with DP alone and combined with ILAT improved aphasia, communication and quality of life as well as associated symptoms of apathy and depression by modulating regions innervated by the left medial, right lateral and brainstem cholinergic pathways.Universidad de Málaga. Campus de Excelencia Internacional AndalucĂa Tech
Ein warhafftige Historien von Zweyen Mewssen (1543)
Die "Warhafftige Historien" (1543) des Protestanten Burkard Waldis reiht sich in das konfessionspolemische Schrifttum des 16. Jahrhunderts ein. Berichtet wird von dem angeblichen Skandal, dass zwei Mäuse durch katholische Geistliche verbrannt worden seien, weil sie die Hostien in einem Kirchentabernakel aufgefressen hätten.
Diese online-Edition bietet eine kritische Textausgabe, eine ausfĂĽhrliche Einleitung sowie einen grĂĽndlichen Wort- und Sachkommentar
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