The Second Demographic Transition in the United States: Exception or Textbook Example?

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/75204/1/j.1728-4457.2006.00146.x.pd

Converting education into earnings: The patterns among Hispanic origin men

We evaluate the functional form of the relationship between education and earnings for Hispanic and non-Hispanic white men to determine whether the payoffs to education vary with level of schooling, and whether credential effects can be discerned. Results indicate that for all groups the usual linear specification, while offering the advantage of parsimony, fits the data less well than more complex models. The levels model best predicts the earnings of Puerto Rican and other Spanish origin workers, while the credential model is best suited for Mexican, Central/South American, and non-Hispanic white men. Credential effects accrue to all groups, except the other Spanish, but Central/South Americans only receive added income bonuses for the completion of a college degree, whereas Mexican, Puerto Rican, and non-Hispanic white men also receive a bonus for a high school diploma.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/24615/1/0000025.pd

Assimilation—On (Not) Turning White: Memory and the Narration of the Postwar History of Japanese Canadians in Southern Alberta

This essay explores understandings of “race” – specifically, what it means to be Japanese – of nisei (“second generation”) individuals who acknowledge their near complete assimilation structurally and normatively into the Canadian mainstream. In historically-contextualized analyses of memory fragments from oral-history interviews conducted between 2011-2017, it focusses on voices and experiences of southern Alberta, an area whose significance to local, national, continental, and trans-Pacific histories of people of Japanese descent is belied by a lack of dedicated scholarly attention. In this light, this essay reveals how the fact of being Japanese in the latter half of the twentieth century was strategically central to nisei lives as individuals and in their communities. In imagining a racial hierarchy whose apex they knew they could never share with the hakujin (whites), the racial heritage they nevertheless inherited and would bequeath could be so potent as to reverse the direction of the colonial gaze with empowering effects in individual engagements then and as remembered now. We see how the narration and validation of one’s life is the navigation of wider historical contexts, the shaping of the post-colonial legacy of Imperial cultures, as Britain and Japan withdrew from their erstwhile colonial projects in Canada

Natural HLA class I ligands from glioblastoma: extending the options for immunotherapy

Glioblastoma multiforme is the most frequent and most malignant primary brain tumor with poor prognosis despite surgical removal and radio-chemotherapy. In this setting, immunotherapeutical strategies have great potential, but the reported repertoire of tumor associated antigens is only for HLA-A 02 positive tumors. We describe the first analysis of HLA-peptide presentation patterns in HLA-A 02 negative glioma tissue combined with gene expression profiling of the tumor samples by oligonucleotide microarrays. We identified numerous candidate peptides for immunotherapy. These are peptides derived from proteins with a well-described role in glioma tumor biology and suitable gene expression profiles such as PTPRZ1, EGFR, SEC61G and TNC. Information obtained from complementary analyses of HLA-A 02 negative tumors not only contributes to the discovery of novel shared glioma antigens, but most importantly provides the opportunity to tailor a patient-individual cocktail of tumor-associated peptides for a personalized, targeted immunotherapeutic approach in HLA-A 02 negative patients