From Infanticide to Activism: The Transformation of Emotions and Identity in Self-Help Movements

Taylor and Leitz trace processes of collective identity construction and politicization among women suffering from postpartum psychiatric illness who have been convicted of infanticide. Joining a growing body of research suggesting that self‐help and consumer health movements can be a significant force for change in both the cultural and political arenas, Taylor and Lietz examine one such movement, a pen‐pal network of women incarcerated for committing infanticide. Taylor and Leitz show how a sense of collective identity fostered by the pen‐pal network triggered a profound emotional transformation in participants, allowing them to convert shame and loneliness into pride and solidarity, and encouraging their participation in efforts to change how the medical and legal system treat postpartum psychiatric illness.https://digitalcommons.chapman.edu/peace_books/1000/thumbnail.jp

Iodothyronine Interactions with the System L1 Amino Acid Exchanger in 3T3-L1 Adipocytes

Thyroid hormones enter isolated white adipocytes largely by a System L1-type amino acid transporter en route to exerting genomic actions. Differentiated 3T3-L1 mouse adipocytes in culture express mRNA for LAT1 (the catalytic subunit of high-affinity System L1). L-[125I]-T3 uptake into 3T3-L1 adipocytes included a substantial saturable component inhibited by leucine. L-[3H]phenylalanine uptake into 3T3-L1 cells was saturable (Km of 31 μM), competitively inhibited by T3 (Ki of 1.2 μM) and blocked by leucine, BCH, and rT3 as expected for substrate interactions of System L1. Efflux of preloaded L-[3H]phenylalanine from 3T3-L1 adipocytes was trans stimulated by external leucine, demonstrating the obligatory exchange mechanism of System L1 transport. T3 (10 μM) did not significantly trans stimulate L-[3H]phenylalanine efflux, but did competitively inhibit the trans stimulatory effect of 10 μM leucine. The results highlight strong competitive interactions between iodothyronines (T3, rT3) and amino acids for transport by System L1 in adipocytes, which may impact cellular iodothyronine exchanges during altered states of protein nutrition

College Debt: An Exploratory Study of Risk Factors Among College Freshmen

The goals of this study are to examine the relationships between loan knowledge, money management skills, debt tolerance attitudes, and student income potential to their willingness to incur educational debt at a mid-western university. The current study showed that freshmen students lacked personal and general loan knowledge and had unrealistic expectations of future income at graduation

Moving from parent consultant to parent collaborator : one pediatric research team\u27s experience.

We share our experiences as academic physical therapists and parents of young people with cerebral palsy working together as a research team, describe and critically review how our working relationship has evolved and propose further enhancements to realize our shared vision. This manuscript is informed by a call for “family-centered research,” transcripts of face-to-face meetings held over a period of 11/2 days, the INVOLVE document and our experiences over almost a decade, as well as other related literature. Authentic collaborative research partnerships between academic researchers and parents embodying trust, mutual respect and shared social responsibility take time and effort to develop and sustain. Rehabilitation research is more meaningful and may be more impactful when strong collaborative partnerships between researchers and health service users are in place

African Entrepreneurs’ Perceptions on the Mentoring Provided by a Cross-cultural Professional Development Experience: Implications for Future Program

We conducted a multicase investigation to assess the impacts of a cross-cultural exchange program on Entrepreneur Fellows from Kenya, South Africa, and Uganda (8 women; 14 men) after they had returned home from the United States. Our assessment included the mentoring aspect of the program. Six questions and related probes guided semi-structured interviews with the 22 Fellows, the study’s quintain. The lead researcher transcribed the study’s interviews and verified accuracy and trustworthiness by sending her transcriptions to the Fellows for verification. Findings derived from the interviews or cases crystallized as themes representative of the quintain. The emergent themes, which included mentoring, inspired two theoretical lenses to guide our interpretation of the Fellows’ experiences: human capital theory and theory of planned behavior. Recommendations for practice include additional training of entrepreneur mentors and suggestions to facilitate high-quality field experiences. Additional research examining participants’ views about mentoring – protégés and their mentors – as an integral component of entrepreneurial training in cross-cultural settings, and how that can be improved, would likely enhance the learning outcomes of similar programs

Characteristics of salivary telomere length shortening in preterm infants

ObjectiveTo examine the association between gestational age, telomere length (TL) and rate of shortening in newborns.Study designGenomic DNA was isolated from buccal samples of 39 term infants at birth and one year and 32 preterm infants at birth, term-adjusted age (40 weeks post-conception) and age one-year corrected for gestational duration. Telomere length was measured by quantitative real-time PCR. Demographic and clinical data were collected during clinic or research visits and from hospital records. Socioeconomic status was estimated using the deprivation category (DEPCAT) scores derived from the Carstairs score of the subject's postal code.ResultsAt birth, preterm infants had longer telomeres than infants born at term. However, there was no difference in telomere length between preterm infants and term infants at one year of age, implying that the rate of telomere shortening was greater in pre-term than term infants. Interestingly, TL at age 40 weeks post-conception in preterm infants was significantly longer than term infant TL at birth, suggesting that time since conception is not the only factor that affects rate of shortening. Several factors, including sex, fetal growth restriction, maternal age, maternal booking body mass index (BMI), mother education level and DEPCAT score, also differed between the preterm and term groups.ConclusionsPreterm infants have longer telomeres than term infants at birth. In the studied cohort, the rate of telomere shortening was greater in the premature group compared with the term infants. This finding agrees with previous studies using cord blood, suggesting that the longer TL in premature infants detected at birth do not persist and demonstrating that use of saliva DNA is acceptable for studies of telomere dynamics in infants. However, that the TL at age 40 weeks post-conception in preterm is longer than term infants at birth suggests that biological factors other than time since conception also affect rate of shortening

Coping with psychological distress during COVID-19: a cautionary note of self-criticalness and personal resilience among healthcare workers

PURPOSE: The COVID-19 pandemic resulted in immense pressure on healthcare workers (HCWs) and healthcare systems worldwide. The current multi-centre evaluation sought to explore the association between coping behaviours and levels of psychological distress among HCWs working during the initial onset of COVID-19. DESIGN/METHODOLOGY/APPROACH: Between April and July 2020 HCWs at three urban hospitals in England were invited to complete an online survey measuring personal and professional characteristics, psychological distress and coping. A principal component analysis (PCA) identified components of coping and structural equation modelling (SEM) was used to test the relationship between components of coping and psychological distress. FINDINGS: A total of 2,254 HCWs participated (77% female, 67% white, 66% in clinical roles). Three components for coping were retained in the PCA analysis: external strategies, internal strategies and self-criticalness/substance use. SEM indicated that internally based coping was associated with lower levels of psychological distress, whereas externally based coping and self-criticalness were associated with greater psychological distress. The final model accounted for 35% of the variance in psychological distress. ORIGINALITY/VALUE: This multi-centre evaluation provides unique insight into the level of psychological distress among HCWs during the initial onset of the COVID-19 pandemic (2020) and associated coping strategies. Addressing self-criticalness and supporting cognitive-based internal coping strategies among HCWs may protect against prolonged exposure to psychological distress. Findings highlight the importance of developing a culture of professional resilience among this vital workforce as a whole rather than placing pressure on an individual's personal resilience