A Trustworthiness of Commercial Airline Pilots (T-CAP) Scale for Indian Consumers

A Trustworthiness of Commercial Airline Pilots (T-CAP) Scale was created for the purpose of measuring consumer perceptions about the trustworthiness of pilots in India. Previous research has used several different types of trust and trustworthiness scales, but none of them focus on pilot trustworthiness, particularly with an Indian consumer base. This paper outlines the process by which we validated the scale and tested reliability. We had 679 participants join in the process of determining the items that belonged in the scale, narrowing down the choices to highly relevant items, and testing the final scale. A factor analysis using the principle components and varimax rotation produced a single factor for the condition of trustworthiness, and all the items strongly loaded on this one factor. Reliability was tested via Cronbach’s Alpha and Guttmann’s Split-half test. Finally, the scale was tested in an experimental setting to determine discriminability. All tests provided evidence of high validity, reliability and discriminability

Deletion of indoleamine 2,3 dioxygenase (Ido)1 but not Ido2 exacerbates disease symptoms of MOG35-55-induced experimental autoimmune encephalomyelitis

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) with pathological features of inflammation, demyelination, and neurodegeneration. Several lines of evidence suggest that the enzymes indoleamine 2,3-dioxygenase (Ido)1 and/or Ido2 influences susceptibility to autoimmune diseases. Deletion of Ido1 exacerbates experimental autoimmune encephalomyelitis (EAE) an animal model of MS. However, no data exist on the role of Ido2 in the pathogenesis of EAE. We investigated whether deletion of Ido2 affected the pathogenesis of EAE. Temporal expression of interferon gamma (Ifng), Ido1 variants, Ido2 variants, as well as genes encoding enzymes of the kynurenine pathway in the spleen and spinal cord of C57BL/6 mice with or without EAE were determined by RT-qPCR. Moreover, EAE was induced in C57BL/6, two Ido1 knockout strains (Ido1KO and Ido1TK) and one Ido2 knockout mouse strain (Ido2−/−) and disease monitored by clinical scores and weight change. Performance on the rotarod was performed on days 0, 5, 10 and 15 post induction. The extent of demyelination in the spinal cord was determined after staining with Oil red O. The development of EAE altered gene expression in both the spleen and spinal cord. Deletion of Ido1 exacerbated the clinical symptoms of EAE. In stark contrast, EAE in Ido2−/− mice did not differ clinically or histologically from control mice. These results confirm a protective role for Ido1, on the pathogenesis of MOG35-55-induced EAE in C57BL/6J mice

Global Organizational Psychology: Internationalizing the Training Curriculum

Due to the rapid of globalization in the Information Age, students must become adept at navigating the complex and ambiguous nature of the global business environment. One major roadblock for training students to become global professionals is the lack of international curriculum within Industrial/Organizational (I/O) Psychology programs at leading post-graduate training institutions. This article examines the methodologies and best practices used in establishing an International I/O Psychology curriculum at the graduate level developed to train students to better understand and work within the complexities of the global business environment. In this article we discuss the process we used to identify the major curriculum components needed for training in international I/O Psychology, and we provide specific advice for programs considering internationalization as well as lessons learned