1,141 research outputs found
State governments start investing capital for entrepreneurs to grow the local economy and keep jobs
State governments – particularly those in “fly-over states” – are supporting state-sponsored investment funds that try to attract investments in local companies in an effort to keep workers and capital from fleeing their states.Venture capital
Measuring Digital Opportunity for America's Children: Where We Stand and Where We Go From Here
Examines the connection between access to technology and the health, economic opportunity, community involvement, and educational achievement of youth. Makes recommendations for addressing the opportunity gap for low-income and ethnic-minority children
Abatement and Transaction Costs of Carbon-Sink Projects Involving Smallholders
Agroforestry projects have the potential to help mitigate global warming by acting as sinks for greenhouse gasses. However, participation in carbon-sink projects may be constrained by high costs. This problem may be particularly severe for projects involving smallholders in developing countries. Of particular concern are the transaction costs incurred in developing projects, measuring, certifying and selling the carbon-sequestration services generated by such projects. This paper addresses these issues by analysing the implications of transaction and abatement costs in carbon-sequestration projects. A model of project participation is developed, which accounts for the conditions under which both buyers and sellers would be willing to engage in a carbon transaction that involves a long-term commitment. The model is used to identify critical project-design variables (minimum project size, farm price of carbon, minimum area of participating farms). A project feasibility frontier (PFF) is derived, which shows the minimum project size that is feasible for any given market price of carbon. The PFF is used to analyse how the transaction costs imposed by the Clean Development Mechanism of the Kyoto Protocol affect project feasibility.Agroforestry, Climate Policy, Carbon Sequestration Costs
An investigation of the operating characteristics of certain heat pumps using water as a heat source
Call number: LD2668 .T4 1950 L56Master of Scienc
Economics of new technologies for sustainable agriculture
Sustainable agriculture is prescribed as a policy approach that maximizes economic benefits while maintaining environmental quality. It is argued that this approach is human capital-intensive and encourages new scientific developments. To attain sustainability, economic incentives for the development and adoption of precision technologies (with minimal residues that cause environmental damage) have to be developed. Taxation and tradeable permits are desirable policies to attain first-best solutions; however, when heterogeneity and lack-of-information problems are significant, alternative institutions have to be developed. The paper presents and discusses such institutions.Farm Management,
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Redox-dependent gating of VDAC by mitoNEET.
MitoNEET is an outer mitochondrial membrane protein essential for sensing and regulation of iron and reactive oxygen species (ROS) homeostasis. It is a key player in multiple human maladies including diabetes, cancer, neurodegeneration, and Parkinson's diseases. In healthy cells, mitoNEET receives its clusters from the mitochondrion and transfers them to acceptor proteins in a process that could be altered by drugs or during illness. Here, we report that mitoNEET regulates the outer-mitochondrial membrane (OMM) protein voltage-dependent anion channel 1 (VDAC1). VDAC1 is a crucial player in the cross talk between the mitochondria and the cytosol. VDAC proteins function to regulate metabolites, ions, ROS, and fatty acid transport, as well as function as a "governator" sentry for the transport of metabolites and ions between the cytosol and the mitochondria. We find that the redox-sensitive [2Fe-2S] cluster protein mitoNEET gates VDAC1 when mitoNEET is oxidized. Addition of the VDAC inhibitor 4,4'-diisothiocyanatostilbene-2,2'-disulfonate (DIDS) prevents both mitoNEET binding in vitro and mitoNEET-dependent mitochondrial iron accumulation in situ. We find that the DIDS inhibitor does not alter the redox state of MitoNEET. Taken together, our data indicate that mitoNEET regulates VDAC in a redox-dependent manner in cells, closing the pore and likely disrupting VDAC's flow of metabolites
Evaluating the differences between elastic net, ridge and lasso regression on empirical asset pricing
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