An Exponential Decay Model for the Deterministic Correlations in Axial Compressors

International audienceThe average-passage equation system (APES) provides a rigorous mathematical framework to account for the UBRI in steady state environment by introducing the deterministic correlations (DC). How to model the DC is the key in APES method. The primary purpose of this study is to develop a DC model for compressor routine design. A 3D viscous unsteady and time-averaging CFD flow solver is developed to investigate the APES technique. Steady, unsteady and time-averaging simulations are conducted on the investigation of the UBRI in the first stage of NASA 67 compressor. Based on DC characteristics and its effects on time-averaged flow, an exponential decay DC model is proposed and implemented into the time-averaging solver. Based on the unsteady simulation, the proposed model is validated by comparing DC distributions and mean flow fields. The comparison indicates that the proposed model can take into account the major part of UBRI and provide significant improvements for predicting spanwise distributions of flow properties in axial compressors, compared with the steady mixing plane method

Experimental Investigation of Flow Control Using Blade End Slots in a Highly Loaded Compressor Cascade

International audienceA detailed experimental investigation is conducted to suppress three-dimensional (3D) corner separation by a proposed passive control method using blade end slots in a highly loaded high-speed compressor cascade. Experiments are carried out under a wide range of incidence angles at Ma=0.59 using blades with and without blade end slots, respectively. Based on the experimental results, extensive comparisons show that the proposed method using blade end slots can efficiently suppress the 3D corner separation and broaden the effective operating range in the highly loaded high-speed compressor cascade. The total pressure loss is significantly reduced under most conditions. The reduction of total pressure loss in the measurement plane is as high as 18.4%, 20.6%, 24.3% and 39.4% at the incidence angle of-1.69˚, 0˚, 2˚ and 4˚, respectively. Furthermore, spanwise distributions of the pitch-averaged total pressure loss and deviation angle as well as the 3D flow field structures are analyzed to reveal the flow control mechanisms using blade end slots. The blade end slots can generate self-adaptive high momentum jet flow through the pressure difference from blade pressure and suction surface. These jet flows from the blade end slots effect downstream along the blade suction surface and significantly increase the flow momentum in the corner region. The main secondary vortex structures are suppressed by the high momentum jet flow; the 3D corner separation is reduced, and the two-dimesionality in the mid-span region is enhanced

Finite-temperature time-dependent variation with multiple Davydov states

The Dirac-Frenkel time-dependent variational approach with Davydov Ans\"atze is a sophisticated, yet efficient technique to obtain an acuurate solution to many-body Schr\"odinger equations for energy and charge transfer dy- namics in molecular aggregates and light-harvesting complexes. We extend this variational approach to finite temperatures dynamics of the spin-boson model by adopting a Monte Carlo importance sampling method. In or- der to demonstrate the applicability of this approach, we compare real-time quantum dynamics of the spin-boson model calculated with that from numerically exact iterative quasiadiabatic propagator path integral (QUAPI) technique. The comparison shows that our variational approach with the single Davydov Ans\"atze is in excellent agreement with the QUAPI method at high temperatures, while the two differ at low temperatures. Accuracy in dynamics calculations employing a multitude of Davydov trial states is found to improve substantially over the single Davydov Ansatz, especially at low temperatures. At a moderate computational cost, our variational approach with the multiple Davydov Ansatz is shown to provide accurate spin-boson dynamics over a wide range of temperatures and bath spectral densities.Comment: 8 pages, 3 figure

Direct numerical simulation of turbulent channel flow with spanwise alternatively distributed strips control

© 2018 World Scientific Publishing Company. The effect of spanwise alternatively distributed strips (SADS) control on turbulent flow in a plane channel has been studied by direct numerical simulations to investigate the characteristics of large-scale streamwise vortices (LSSVs) induced by small-scale active wall actuation, and their potential in suppressing flow separation. SADS control is realized by alternatively arranging out-of-phase control (OPC) and in-phase control (IPC) wall actuations on the lower channel wall surface, in the spanwise direction. It is found that the coherent structures are suppressed or enhanced alternatively by OPC or IPC, respectively, leading to the formation of a vertical shear layer, which is responsible for the LSSVs' presence. Large-scale low-speed region can also be observed above the OPC strips, which resemble large-scale low-speed streaks. LSSVs are found to be in a statistically-converged steady state and their cores are located between two neighboring OPC and IPC strips. Their motions contribute significantly to the momentum transport in the wall-normal and spanwise directions, demonstrating their potential ability to suppress flow separation

Heparin-binding epidermal growth factor inhibits apoptosis in cisplatin-resistant pancreatic cancer cells via upregulation of EGFR and ERCC 1 expressions

Purpose: To investigate the influence of heparin-binding epidermal growth factor (HB-EGF) on apoptosis in cisplatin-resistant pancreatic cancer cells, as well as its mechanism of action. Methods: Pancreatic cancer cisplatin-resistant cells (BXPC-3/CDDP) were transfected with HB-EGF small interfering RNA (siRNA). The cells were randomly assigned to four groups, namely, BXPC-3 group (group A), BXPC-3/CDDP group (group B), transfected group A (group Asi) and transfected group B (group Bsi). Cell proliferation was determined using MTT assay, and the levels of expression of HBEGF, epidermal growth factor receptor (EGFR) and excision repair cross-complementation group 1 (ERCC 1) were determined using Western blotting. The extent of apoptosis was determined by flow cytometry. Results: Cell proliferation was increased in group B, relative to group A, but was significantly decreased after transfection with HB-EGF siRNA (p < 0.05). The half-maximal inhibitory concentration (IC50) of group Bsi was reduced, relative to group Asi (p < 0.05). The expression of HB-EGF was significantly upregulated in group B, relative to group A (p < 0.05). In contrast, HB-EGF siRNA transfection of the cells significantly down-regulated HB-EGF expression (p < 0.05). Early apoptosis was significantly higher in group A than in groups B and Bsi. Higher levels of apoptosis were seen in group Bsi, relative to group B after inhibition of HB-EGF expression (p < 0.05). Conclusion: These results indicate that HB-EGF is resistant to cisplatin, and it inhibits apoptosis in pancreatic cancer cells via the upregulation of EGFR and ERCC 1 expressions

Direct numerical simulation of supersonic turbulent flows around a tandem expansion-compression corner

© 2015 AIP Publishing LLC. The M = 2.9 supersonic turbulent flows over a tandem expansion-compression corner configuration with a sharp deflection angle of 25° at three Reynolds numbers Reδ = 20 000, 40 000, and 80 000 were studied by using direct numerical simulation. The flow statistics were validated against available experimental measurements and other numerical predictions. The flow structures and turbulence statistics were detailed visualized and analysed for the Reδ = 40 000 case, especially in the interaction region where flow separation and reattachment occurred. It was found that during the expansion process, the boundary layer exhibited a characteristic two-layer structure also discovered in previous experimental studies, and the turbulence evolved differently within these two layers. In the outer layer, the turbulence was consistently suppressed along the ramp to a large extent, while in the inner layer, it was suppressed only in a small region around the expansion corner, and the near-wall quasi-streamwise vortices were well preserved. Flow patterns near the reattachment line have shown the existence of the Görtler-type vortices, which would largely amplify turbulence fluctuations in the near-wall region, thus promoting the regeneration of wall turbulence that in turn contributed to the redevelopment of a downstream turbulent boundary layer. The Reynolds number effects and the characteristics of coherent structures were also discussed. With the increase of the Reynolds number, the separation bubble size decreased, but the pattern and the characteristic size of wall streamlines near the reattachment line were preserved

Flow separation control over a rounded ramp with spanwise alternating wall actuation

An implicit large-eddy simulation is carried out to study turbulent boundary-layer separation from a backward-facing rounded ramp with active wall actuation control. This method, called spanwise alternating distributed strips control, is imposed onto the flat plate surface upstream of a rounded ramp by alternatively applying out-of-phase control and in-phase control to the wall-normal velocity component in the spanwise direction. As a result, the local turbulence intensity is alternatively suppressed and enhanced, leading to the creation of vertical shear-layers, which is responsible for the presence of large-scale streamwise vortices. These vortices exert a predominant influence on the suppression of the flow separation. The interaction between the large-scale vortices and the downstream recirculation zone and free shear-layer is studied by examining flow statistics. It is found that in comparison with the non-controlled case the flow separation is delayed, the reattachment point is shifted upstream, and the length of the mean recirculation zone is reduced up to 8.49%. The optimal control case is achieved with narrow in-phase control strips. An in-depth analysis shows that the delay of the flow separation is attributed to the activation of the near-wall turbulence by the in-phase control strips and the improvement of the reattachment location is mainly due to the large-scale streamwise vortices, which enhance the momentum transport between the main flow and separated region