Tissue Sodium Content and Arterial Hypertension in Obese Adolescents

Early-onset obesity is known to culminate in type 2 diabetes, arterial hypertension and subsequent cardiovascular disease. The role of sodium (Na+) homeostasis in this process is incompletely understood, yet correlations between Na+ accumulation and hypertension have been observed in adults. We aimed to investigate these associations in adolescents. A cohort of 32 adolescents (13-17 years), comprising 20 obese patients, of whom 11 were hypertensive, as well as 12 age-matched controls, underwent 23Na-MRI of the left lower leg with a standard clinical 3T scanner. Median triceps surae muscle Na+ content in hypertensive obese (11.95 mmol/L [interquartile range 11.62-13.66]) was significantly lower than in normotensive obese (13.63 mmol/L [12.97-17.64]; p = 0.043) or controls (15.37 mmol/L [14.12-16.08]; p = 0.012). No significant differences were found between normotensive obese and controls. Skin Na+ content in hypertensive obese (13.33 mmol/L [11.53-14.22] did not differ to normotensive obese (14.12 mmol/L [13.15-15.83]) or controls (11.48 mmol/L [10.48-12.80]), whereas normotensive obese had higher values compared to controls (p = 0.004). Arterial hypertension in obese adolescents is associated with low muscle Na+ content. These findings suggest an early dysregulation of Na+ homeostasis in cardiometabolic disease. Further research is needed to determine whether this association is causal and how it evolves in the transition to adulthood

Arecibo Observations of Formaldehyde in L1551

We report observations of the formaldehyde (H2CO) 6 cm (4.8 GHz) line toward L1551. The observations were conducted with the Arecibo Telescope (beam FWHP ~ 1') to verify the tentative detection of H2CO thermal emission reported by Duncan and collaborators in 1987. The H2CO emission lines were expected to be present with a signal-to-noise ratio of 10 in our spectra. However, we did not detect H2CO emission; i.e., our data rule out their tentative detection. The absence of H2CO emission is also confirmed by the fact that the H2CO line profiles at the two positions of expected emission are well fitted by a single absorption component (accounting for the hyperfine structure of the line) in one of the positions and by a single absorption line plus a red-wing absorption component in the second position. The Orion BN/KL region remains the only H2CO 6 cm thermal emitter known. Our observations also demonstrate that the H2CO 6 cm absorption line traces not only the quiescent molecular cloud but also the kinematics associated with the star formation process in L1551-IRS 5

Thermal Methanol Observations of the Outflow from the G31.41+0.31 Hot Molecular Core

The G31.41+0.31 region hosts one of the most prominent hot molecular cores known. Coincident with the hot molecular core is an outflow whose orientation has been controversial. We report VLA-C observations of thermal methanol (70–61 A+, 44 GHz) toward the position of the G31.41+0.31 hot molecular core. Our goals are to clarify the orientation of the outflow and to study the properties of a molecular outflow from a very young region of massive star formation. We confirm that the outflow is indeed associated with the hot molecular core. Our observations strongly suggest that the outflow is oriented in the northeast-southwest direction. The outflow is massive (15 M☉), with a dynamical time of the order of ~4 × 103 yr, and has a wide-angle bipolar morphology

Event-driven management algorithm of an Engineering documents circulation system

Development methodology of an engineering documents circulation system in the design company is reviewed. Discrete event-driven automatic models using description algorithms of project management is offered. Petri net use for dynamic design of projects is offered

A Search for Formaldehyde 6 cm Emission toward Young Stellar Objects. II. H2CO and H110α Observations

We report the results of our second survey for Galactic H2CO maser emission toward young stellar objects. Using the GBT and the VLA in the A configuration we observed 58 star-forming regions and discovered the fifth H2CO 6 cm maser region in the Galaxy (G23.71-0.20). We have discussed the detection toward G23.71-0.20 in a previous paper. Here we present all the other results from our survey, including detection of H2CO absorption features toward 48 sources, detection of the H110α recombination line toward 29 sources, detection (including tentative detections) of the carbon recombination line C110α toward 14 sources, subarcsecond angular resolution images of 6 cm continuum emission toward five sources, and observations of the H2CO masers in IRAS 18566+0408 and NGC 7538. In the case of NGC 7538, we detected the two main H2CO maser components, and our observations confirm variability of the blueshifted component recently reported by Hoffman et al. The variability of both maser components in NGC 7538 could be caused by a shock wave that reached the redshifted component approximately 14 yr before reaching the blueshifted component. If that were the case, we would expect to detect an increase in the flux density rate of change of the blueshifted component sometime after the year 2009. Our data also support the use of H2CO/H110α observations as a tool to resolve the kinematic distance ambiguity of massive star-forming regions in the Galaxy