Public finance, trade, and development : what have we learned?

Interdependence of trade and public finance policy are important considerations in designing macroeconomic policy, public revenue policy, and public expenditure policy. A competitive real exchange rate, improved trade performance, and trade liberalization are all built on the base of sound fiscal management. Trade policies and trade liberalization may, however have a negative effect on fiscal balances, which must be considered and compensated for. Improving competitiveness and reducing protection is likely to involve reform of both trade tariffs and domestic taxation. Greater reliance on efficiently designed user charges will also help make a country more competitive internationally. Correct priorities should be set for public expenditures - whether they are rising or falling - to ensure that they are supportive of trade and of tradeable goods production.Public Sector Economics&Finance,TF054105-DONOR FUNDED OPERATION ADMINISTRATION FEE INCOME AND EXPENSE ACCOUNT,Banks&Banking Reform,Environmental Economics&Policies,Economic Theory&Research

Spoken words

Chiefly tablesIncludes bibliographical referencesSupported in part by the National Institute of Education under contract no. US-NIE-C-400-76-011

Consideration of Reinforcer Magnitude with Respect to Preference and Reinforcer Assessment Outcomes

This study examined the correspondence between preference for systematically differing magnitudes of edible stimuli and relative progressive ratio (PR) breakpoints. A primary MSWO preference assessment was used to rank eight different edible items. Next, a secondary MSWO preference assessment determined preference for 0.5, 2, and 10 g of HP and LP items. Following a baseline phase, 0.5, 2, and 10 g of both the HP and LP items (i.e., six stimuli total) were tested individually under PR reinforcer assessment administrations. In contrast to previous research, there was not a direct correspondence between preference and PR breakpoints. In addition, HP stimuli did not consistently produce higher breakpoints when compared to LP stimuli, irrespective of magnitude

Assessments and Accountability (Condensed version)

Accessed 67,381 times on https://pareonline.net from January 16, 2001 to December 31, 2019. For downloads from January 1, 2020 forward, please click on the PlumX Metrics link to the right

A Nicotinic Acetylcholine Receptor Agonist Prevents Loss of Retinal Ganglion Cells in a Glaucoma Model

Purpose.: The purpose of this study was to analyze the neuroprotective effect of an α7 nAChR agonist, PNU-282987, using an in vivo model of glaucoma in Long Evans rats. Methods.: One eye in each animal was surgically manipulated to induce glaucoma in control untreated animals and in animals that were treated with intravitreal injections of PNU-282987. To induce glaucoma-like conditions, 0.05 mL of 2 M NaCl was injected into the episcleral veins of right eyes in each rat to create scar tissue and increase intraocular pressure. The left eye in each rat acted as an internal control. One month following NaCl injection, rats were euthanized, retinas were removed, flatmounted, fixed, and nuclei were stained with cresyl violet or RGCs were immunostained with an antibody against Thy 1.1 or against Brn3a. Stained nuclei in the RGC layer and labeled RGCs in NaCl-injected retinas were counted and compared with cell counts from untreated retinas in the same animal. Results.: NaCl injections into the episcleral veins caused a significant loss of cells by an average of 27.35% (±2.12 SEM) in the RGC layer within 1 month after NaCl injection, which corresponded to a significant loss of RGCs. This loss of RGCs was eliminated if 5 μL of 100 μM PNU-282987 was injected into the right eye an hour before NaCl injection. Conclusions.: The results from this study support the hypothesis that the α7 agonist, PNU-282987, has a neuroprotective effect in the rat retina. PNU-282987 may be a viable candidate for future therapeutic treatments of glaucoma

Prevention of Glaucoma-Induced Retinal Ganglion Cell Loss Using Alpha7 nAChR Agonists

In this study, the neuroprotective effect of various nicotinic alpha7 acetylcholine receptor agonists in an in-vivo model of glaucoma using adult Long Evans rats was analyzed. Glaucoma-like conditions were induced in the eyes of Long Evans rats after injection of hypertonic saline into episcleral veins to create scar tissue and increase the animal’s intraocular pressure. This procedure produced significant loss of retinal ganglion cells within one month and was associated with an increase of intraocular pressure. Using this model system, various alpha7 nicotinic acetylcholine receptor (a7 nAChR) agonists were applied at different doses as eye drops to the right eye of adult Long Evans rats while the left eye was left as an internal control. The a7 nAChR agonists used in this study prevented loss of RGCs in a dose dependent manner after the procedure to induce glaucoma-like conditions. PHA-543613 and PNU- 282987 provided the largest degree of RGC survival after inducing glaucomalike conditions, followed by nicotine, SEN 12333, tropisetron, 3-Bromocytisine and DMAB. To provide evidence that neuroprotection of RGCs was mediated through activation of a7 nAChR, in some studies different concentrations of the a7 nAChR antagonist, MLA, was intravitreally injected into experimentally treated eyes before initiation of eye drops and the procedure to induce glaucoma-like conditions. In the presence of MLA, RGC neuroprotection was blocked. Results from these studies suggest that selective a7 nAChR agonists may be used in future therapeutic treatments for glaucoma or other CNS diseases associated with a7 nAChRs

Small-amplitude normal modes of a vortex in a trapped Bose-Einstein condensate

We consider a cylindrically symmetric trap containing a small Bose-Einstein condensate with a singly quantized vortex on the axis of symmetry. A time-dependent variational Lagrangian analysis yields the small-amplitude dynamics of the vortex and the condensate, directly determining the equations of motion of the coupled normal modes. As found previously from the Bogoliubov equations, there are two rigid dipole modes and one anomalous mode with a negative frequency when seen in the laboratory frame.Comment: 4 pages, no figures, Revte

Vortex stabilization in a small rotating asymmetric Bose-Einstein condensate

We use a variational method to investigate the ground-state phase diagram of a small, asymmetric Bose-Einstein condensate with respect to the dimensionless interparticle interaction strength $\gamma$ and the applied external rotation speed $\Omega$. For a given $\gamma$, the transition lines between no-vortex and vortex states are shifted toward higher $\Omega$ relative to those for the symmetric case. We also find a re-entrant behavior, where the number of vortex cores can decrease for large $\Omega$. In addition, stabilizing a vortex in a rotating asymmetric trap requires a minimum interaction strength. For a given asymmetry, the evolution of the variational parameters with increasing $\Omega$ shows two different types of transitions (sharp or continuous), depending on the strength of the interaction. We also investigate transitions to states with higher vorticity; the corresponding angular momentum increases continuously as a function of $\Omega$

Polarization measurements on irradiated ammonia

The polarization characteristics of ammonia irradiated at liquid helium temperatures and subsequently used in a scattering experiment are discussed.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/87408/2/488_1.pd