早期使用脱水剂干预治疗具有重症倾向手足口病的临床研究

Objective: To investigate new ways and new measures to treat foot and mouth disease, to reduce the occurrence of severe cases, thereby reducing the mortality. Methods: Using double blind, control group randomly selected cases, treated with mannitol plus routine treatment, the control group with conventional therapy. Results: the group of mannitol plus routine treatment all discharged, and no cases were converted into severe cases, while the half of the control group were converted into severe cases, plus mannitol after remission and cured, and the control group was significantly prolonged duration of about 10 days. Conclusion: We believe that children with tendency of hand foot and mouth disease should be treated with mannitol in the early period. It can reduce hospitalization time and prevent hand foot and mouth disease development so that the case fatality rate is greatly reduced, and it is worthy of popularization and application.目的  探讨手足口病治疗新途径、新措施，减少重症病例的发生，从而减少死亡率。方法  采用双盲对照组随机选择病例，治疗组采用甘露醇加常规治疗，对照组则采用常规治疗。结果  采用甘露醇加常规治疗的治疗组全部康复出院，且无一例转为重症病例，而对照组大约一半转为重症病例，加用甘露醇后缓解并治愈出院，而且病程对照组明显延长约10天左右。结论  我们认为早期对手足口病具有重症倾向的患儿使用甘露醇治疗效果好，可减少住院时间及向重症手足口病发展，从而使病死率大大减少，值得推广应用

Perioperative Stroke Following General Surgery

AbstractPerioperative stroke is rare; however, patients undergoing cardiovascular surgery are considered to be at high risk for perioperative stroke. Here, we outline a case where perioperative stroke occurred following total hip replacement surgery. The risk factors and possible causes of the stroke in this patient are discussed. In addition, we reiterate the appropriate management approaches needed to prevent perioperative stroke. Briefly, the importance of precise preoperative evaluation and of proper intraoperative and postoperative management should not be overlooked. Finally, it is important to realize that decreasing perioperative strokes and the disabilities associated with them will lower the financial burden on families and the community

Multicriteria Resource Brokering in Cloud Computing for Streaming Service

By leveraging cloud computing such as Infrastructure as a Service (IaaS), the outsourcing of computing resources used to support operations, including servers, storage, and networking components, is quite beneficial for various providers of Internet application. With this increasing trend, resource allocation that both assures QoS via Service Level Agreement (SLA) and avoids overprovisioning in order to reduce cost becomes a crucial priority and challenge in the design and operation of complex service-based platforms such as streaming service. On the other hand, providers of IaaS also concern their profit performance and energy consumption while offering these virtualized resources. In this paper, considering both service-oriented and infrastructure-oriented criteria, we regard this resource allocation problem as Multicriteria Decision Making problem and propose an effective trade-off approach based on goal programming model. To validate its effectiveness, a cloud architecture for streaming application is addressed and extensive analysis is performed for related criteria. The results of numerical simulations show that the proposed approach strikes a balance between these conflicting criteria commendably and achieves high cost efficiency

An Integrated Web-based System for MEDLINE Analysis: A Case Study of Chronic Kidney Disease

In the era of big data, medical researchers attempt to utilize some analysis techniques like machine learning and text mining on their large-scale corpora to save valuable labor work and time. Consequently, many data analysis platforms are built to support medical professionals such as Pubtator, GeneWays, BioContext, etc. These platforms are helpful to medical entities recognition and relation extraction, but there is not an integrated platform to support researchers’ various needs, and medical projects are isolated from each other, which is hard to be shared and reused. As a result, we present an integrated system containing ‘name entity recognition’, ‘document categorization’ and ‘association extraction’. Besides, we add the concept of ‘socialization’ making projects reusable for further analyses. A case study of chronic kidney disease was adopted to indicate the effectiveness of the proposed system

A dinuclear copper complex: bis­(μ-4-amino­benzoato)bis­[aqua(1,10-phenanthroline)copper(II)] dichloride bis(4-amino­benzoic acid) dihydrate

The title complex, [Cu2(C7H6NO2)2(C12H8N2)2(H2O)2]·2C7H7NO2·2H2O, consists of a dinuclear [Cu2(C7H6NO2)2(C12H8N2)2(H2O)2]2+ cation, two Cl− anions, two 4-amino­benzoic acid mol­ecules and two disordered water mol­ecules (site occupancy factors 0.5). The Cu(II) ion adopts a distorted square-pyramidal geometry formed by two N atoms from the 1,10-phenanthroline ligand and two O atoms of the two 4-amino­benzoic acid ligands and one water O atom. The Cu⋯Cu separation is 3.109 (2) Å. A twofold axis passes through the mid-point of the Cu⋯Cu vector