4 research outputs found

    Additional file 2: of South African HIV-1 subtype C transmitted variants with a specific V2 motif show higher dependence on α4β7 for replication

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    IECs and IMCs show similar binding to and dependence on α4β7 for replication. IECs and IMCs of CAP210 T/F and CAP239 T/F bound to α4β7 at similar levels as defined by (A) p24 binding assay where the dashed line represents IMC binding and the solid line represents IEC binding and (B) the competition assay. SF162 IEC and IMC also bound similarly see Figure 1A. (C) All three viruses showed no differences between their IECs and respective IMCs in dependence on α4β7 for replication. All results are representative of three experiments with error bars representing SEM. No differences were significant by the paired t test

    Additional file 2 of Lactic acid from vaginal microbiota enhances cervicovaginal epithelial barrier integrity by promoting tight junction protein expression

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    Additional file 2: Supplementary Table 1. Proteins with significantly different abundance in women with high as compared to low L-LDH and D-LDH abundance*. Supplementary Table 2. Barrier-related proteins with significantly different abundance in women with high as compared to low L-LDH abundance*. Supplementary Table 3. Genes differentially expressed by L-LA, D-LA and HCL treatment of Ect cells*. Supplementary Table 4. Gene ontology pathways significantly enriched by L-LA and D-LA treatment of Ect cells. Supplementary Table 5. Tight junction genes differentially expressed by L-LA, D-LA and HCL treatment of Ect cells*. Supplementary Table 6. Tight junction genes differentially expressed by treatment of VK2 cells with bacterial culture supernatants*
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