IECs and IMCs show similar binding to and dependence on α4β7 for replication. IECs and IMCs of CAP210 T/F and CAP239 T/F bound to α4β7 at similar levels as defined by (A) p24 binding assay where the dashed line represents IMC binding and the solid line represents IEC binding and (B) the competition assay. SF162 IEC and IMC also bound similarly see Figure 1A. (C) All three viruses showed no differences between their IECs and respective IMCs in dependence on α4β7 for replication. All results are representative of three experiments with error bars representing SEM. No differences were significant by the paired t test
