Needs Assesment of Adolescent Health Services

Health problems surround the adolescent rises everytime, yet it does unexcelled with their awareness or knowledge about that problems. The adolescent health service that are poorly accesced by the adolescent become the indicator that proves that the adolescent health services are not fully known and utilized yet. The assesment of adolesccent health services need has to be done so that it can be fully understand by the helper, target and stakeholder. This study aimed to analyse the adolescent health service need in Karang Bendo, Banguntapan, Bantul, Yogyakarta, Indonesia. The study was conducted in 2016 using cross-sectional approach. The results revealed that the level of adolsecent\u27s knowledge are still relatively poor: reproductive health knowledge (44.1%), HIV/AIDS (41.2%), smoke (50%), drugs (58.8%), and healthy lifestyle () (47.1%). The majority of respondents said that they need health services about reproduction health (94.1%), HIV/AIDS (91.2%), smoke (91.2%), drugs (88.2%) and healthy lifestyle (91.2%)

The Long-term Stability of Class II Cases Treated in a Private Practice Using a Straightwire Appliance: A Dental Cast Analysis

Achieving long-term stability after orthodontic treatment is a major challenge for orthodontists. The previous literature shows that relapse occurs at a considerable magnitude. The purpose of the present study was to determine the amount and type of long-term, posttreatment relapse that occurs in a homogeneous group of patients treated by a single experienced orthodontist in a private practice setting. Dental casts from a sample of 30 Class II division 1 Caucasian females treated without extractions were evaluated at pretreatment (mean age = 13.1 years), posttreatment (mean age = 15.9 years) and recall (mean age = 28.3 years) to determine the nature and extent of long-term posttreatment changes. All of the subjects were treated in the private practice of a single, experienced practitioner in Southaven, MS. The dental casts were examined to investigate changes in overbite, overjet, midline deviation, buccal segment relationships, canine relationships, incisor irregularity, arch chord lengths, curve of spee, arch depths and arch widths that occurred at an average of 12 years posttreatment. Overjet increased slightly after treatment, but the mean overjet at recall examination was within acceptable limits. Overbite deepened after treatment. About 1/3 (37%) of the treatment correction in overbite was lost during the posttreatment interval. A relapse of only 37% in the present sample was more favorable than the relapse percentages reported in previous studies. Maxillary Incisor Irregularity was relatively stable (10% relapse), but 67% of treatment correction in lower incisor irregularity was lost during the recall interval. Little et al. (1981) suggested that less than 30% of cases maintain satisfactory mandibular alignment with an Irregularity Index of less than 3.5 mm at 10 years posttreatment. The present study found that 13 out of the 30 cases evaluated (43%) had Incisor Irregularity of less than 3.5 mm at the recall examination. Maxillary arch chords (1‑3 and 1‑6) were stable while mandibular 1-3 chord was unstable. Nearly all of the treatment increase in mandibular 1‑3 chord was lost during the posttreatment interval. Curve of Spee correction during treatment was stable over the long-term with less than 10% of the correction deepening over time. Although increased during treatment, maxillary arch widths were stable over the long-term. The mandibular arch widths were less stable. 50% of mandibular intercanine expansion during treatment was lost over the long-term. This was a similar finding to previous studies. Buccal segment relationship and canine relationship improved from class II toward class I during treatment and did not show relapse toward class II over the long-term. In fact, the subjects continued to grow favorably toward a more class I relationship over the long-term

A study of German-Austrian refugees in Louisville, Kentucky.

This paper will deal with the adjustment of refugees in an American middle-sized city, Louisville, Kentucky. It will attempt to touch the background and past of the group, but it will be pointed to a question which indeed is vital to each refugee: What does he make of his life after immigration? Can what was in origin compulsory, become constructive for the future? Will America for him be more than a haven of refuge after a harassing persecution - will it be a home for him and his children? And the answer to these questions is inextricably tied up with the other aspect of immigration: What, if any, contribution to America will these immigrants be able to make? What are their assets and liabilities? How do they compare with previous immigrants? How do they fit into the general and present socio-economic picture of American life? This paper endeavors to furnish some factual material to answer these questions in a sample case, for such we might consider the immigration to Louisville where immigration developed according to its own laws, supported by an active committee, but not fostered beyond the natural trends. We think that to look at the adjustment of refugees in such a community will give a more typical picture than to examine a larger city with its disproportionate numbers of refugees, since in such a setting the refugees appear as a mass unrelated to the American population as a whole, and the problems which the group may actually present are numerically exaggerated

Seasted: Ciudad Flotante Desarrollo innovador para un nuevo modelo de ciudad

Seastead is a floating city experiment for international waters based on economic studies carried out by the Seasteading Institute, which seeks to increase real estate market growth, driven by an economic incentive dedicated to medical tourism, aquaculture, technology incubators, and support platforms for offshore rigs. A new pre-conceptual model of a floating city was created, conceptualizing an analysis of the floating habitat as a means for development and expansion. is new habitat style was designed taking into account considerations of the marine habitat, current habitats, utopian projects and studies regarding the expansion of urban spaces. e city was designed on a semi-submersible offshore platform chosen through a parametric model made by the Seasteading Institute, which allowed for a final modular array comprised by 300 containers organized by a crane system, this being the organizational system of the city. Seasted presenta el experimento de una ciudad flotante en aguas internacionales con base en estudios realizados por el instituto Seasteading, el cual busca incrementar el crecimiento de mercado en bienes raíces, conducido por un incentivo económico dedicado al turismo médico, acuicultura, incubadoras de tecnología y apoyo para las plataformas de perforación costa afuera. Un nuevo modelo pre-conceptual de ciudad flotante fue creado, conceptualizando un análisis de hábitat flotante como medio de desarrollo y expansión. Este nuevo estilo de entorno habitacional fue diseñado teniendo en cuenta consideraciones del ambiente marino, hábitat actual, estudios utópicos y estudios referentes a expansión de espacios urbanos. La ciudad fue diseñada en una plataforma semi-sumergible costa afuera elegida a través de un modelo paramétrico realizado por el instituto Seasteding, el cual permitió una formación modular final compuesta por 300 contenedores organizado por un sistema de grúas, siendo este el sistema organizacional de la ciudad.

RF-Powered Cognitive Radio Networks: Technical Challenges and Limitations

The increasing demand for spectral and energy efficient communication networks has spurred a great interest in energy harvesting (EH) cognitive radio networks (CRNs). Such a revolutionary technology represents a paradigm shift in the development of wireless networks, as it can simultaneously enable the efficient use of the available spectrum and the exploitation of radio frequency (RF) energy in order to reduce the reliance on traditional energy sources. This is mainly triggered by the recent advancements in microelectronics that puts forward RF energy harvesting as a plausible technique in the near future. On the other hand, it is suggested that the operation of a network relying on harvested energy needs to be redesigned to allow the network to reliably function in the long term. To this end, the aim of this survey paper is to provide a comprehensive overview of the recent development and the challenges regarding the operation of CRNs powered by RF energy. In addition, the potential open issues that might be considered for the future research are also discussed in this paper.Comment: 8 pages, 2 figures, 1 table, Accepted in IEEE Communications Magazin

Energy Detection of Unknown Signals over Cascaded Fading Channels

Energy detection is a favorable mechanism in several applications relating to the identification of deterministic unknown signals such as in radar systems and cognitive radio communications. The present work quantifies the detrimental effects of cascaded multipath fading on energy detection and investigates the corresponding performance capability. A novel analytic solution is firstly derived for a generic integral that involves a product of the Meijer $G-$function, the Marcum $Q-$function and arbitrary power terms. This solution is subsequently employed in the derivation of an exact closed-form expression for the average probability of detection of unknown signals over $N$*Rayleigh channels. The offered results are also extended to the case of square-law selection, which is a relatively simple and effective diversity method. It is shown that the detection performance is considerably degraded by the number of cascaded channels and that these effects can be effectively mitigated by a non-substantial increase of diversity branches.Comment: 12 page

CDH1 regulates E2F1 degradation in response to differentiation signals in keratinocytes

The E2F1 transcription factor plays key roles in skin homeostasis. In the epidermis, E2F1 expression is essential for normal proliferation of undifferentiated keratinocytes, regeneration after injury and DNA repair following UV radiation-induced photodamage. Abnormal E2F1 expression promotes nonmelanoma skin carcinoma. In addition, E2F1 must be downregulated for proper keratinocyte differentiation, but the relevant mechanisms involved remain poorly understood. We show that differentiation signals induce a series of post-translational modifications in E2F1 that are jointly required for its downregulation. Analysis of the structural determinants that govern these processes revealed a central role for S403 and T433. In particular, substitution of these two amino acid residues with non-phosphorylatable alanine (E2F1 ST/A) interferes with E2F1 nuclear export, K11- and K48-linked polyubiquitylation and degradation in differentiated keratinocytes. In contrast, replacement of S403 and T433 with phosphomimetic aspartic acid to generate a pseudophosphorylated E2F1 mutant protein (E2F1 ST/D) generates a protein that is regulated in a manner indistinguishable from that of wild type E2F1. Cdh1 is an activating cofactor that interacts with the anaphase-promoting complex/cyclosome (APC/C) ubiquitin E3 ligase, promoting proteasomal degradation of various substrates. We found that Cdh1 associates with E2F1 in keratinocytes. Inhibition or RNAi-mediated silencing of Cdh1 prevents E2F1 degradation in response to differentiation signals. Our results reveal novel regulatory mechanisms that jointly modulate post-translational modifications and downregulation of E2F1, which are necessary for proper epidermal keratinocyte differentiation

E2F1 interactions with hHR23A inhibit its degradation and promote DNA repair

Nucleotide excision repair (NER) is a major mechanism for removal of DNA lesions induced by exposure to UV radiation in the epidermis. Recognition of damaged DNA sites is the initial step in their repair, and requires multiprotein complexes that contain XPC and hHR23 proteins, or their orthologues. A variety of transcription factors are also involved in NER, including E2F1. In epidermal keratinocytes, UV exposure induces E2F1 phosphorylation, which allows it to recruit various NER factors to sites of DNA damage. However, the relationship between E2F1 and hHR23 proteins vis-à-vis NER has remained unexplored. We now show that E2F1 and hHR23 proteins can interact, and this interaction stabilizes E2F1, inhibiting its proteasomal degradation. Reciprocally, E2F1 regulates hHR23A subcellular localization, recruiting it to sites of DNA photodamage. As a result, E2F1 and hHR23A enhance DNA repair following exposure to UV radiation, contributing to genomic stability in the epidermis

NETCU: analising e-Learning neworked curricula in Europe: the importance of legal and quality assurance aspects

Conferência realizada no Porto de 6-9 de junho de 2012info:eu-repo/semantics/publishedVersio