Dual-channel attribute graph clustering beyond the homogeneity assumption

In recent years, significant progress has been made in the research of attribute graph clustering. However, existing methods are mostly based on the homogeneity assumption, thereby neglecting the application scenarios of heterogeneous graphs, leading to the loss of high-frequency information and poor clustering results during the clustering process. To address this issue, a novel dual-channel attribute graph clustering (DCAGC) method was proposed. A mixture of Gaussian models was used to predict the homogeneity of node connections and two views of homogeneous and heterogeneous were built, based on this prediction to capture low-frequency and high-frequency information in the graph from different perspectives. Simultaneously, by integrating contrastive learning and clustering, more precise node embeddings were achieved. Compared to other methods, DCAGC demonstrates significant clustering performance when handling heterogeneous graph datasets and exhibits strong resilience to anomalous connections

The Involvement of Notch1-RBP-Jk/Msx2 Signaling Pathway in Aortic Calcification of Diabetic Nephropathy Rats

Background. This study explored the changes in expression of vascular smooth muscle cell (VSMC) markers and osteogenic markers, as well as the involvement of Notch1-RBP-Jk/Msx2 pathway in a rat model of diabetic nephropathy (DN) with vascular calcification. Methods. A rat model of DN with concomitant vascular calcification was created by intraperitoneal injection of streptozotocin followed by administration of vitamin D3 and nicotine. Biochemical analysis and histological examination of aortic tissue were performed. VSMC markers and osteogenic markers as well as target molecules in Notch1-RBP-Jk/Msx2 were determined by quantitative real-time polymerase chain reaction and immunohistochemical analysis. Results. Serum calcium and phosphorus levels were significantly increased in model rats as compared to that in normal controls. Diabetic rats with vascular calcification exhibited mineral deposits in aortic intima-media accompanied by decreased expression of VSMC markers and increased expression of osteogenic markers. Notch1, RBP-Jk, Msx2, Jagged1, and N1-ICD were barely expressed in the aortic wall of normal rats. In contrast, these were significantly increased in the model group at all time points (8, 12, and 16 weeks), as compared to that in the normal rats. Conclusion. Activation of the Notch1-RBP-Jk/Msx2 signaling pathway may be involved in the development and progression of vascular calcification in DN

Anthropogenic Activities Generate High-Refractory Black Carbon along the Yangtze River Continuum

12 pages, 7 figuresCombustion-driven particulate black carbon (PBC) is a crucial slow-cycling pool in the organic carbon flux from rivers to oceans. Since the refractoriness of PBC stems from the association of non-homologous char and soot, the composition and source of char and soot must be considered when investigating riverine PBC. Samples along the Yangtze River continuum during different hydrological periods were collected in this study to investigate the association and asynchronous combustion drive of char and soot in PBC. The results revealed that PBC in the Yangtze River, with higher refractory nature, accounts for 13.73 ± 6.89% of particulate organic carbon, and soot occupies 37.53 ± 11.00% of PBC. The preponderant contribution of fossil fuel combustion to soot (92.57 ± 3.20%) compared to char (27.55 ± 5.92%), suggested that fossil fuel combustion is a crucial driver for PBC with high soot percentage. Redundancy analysis and structural equation modeling confirmed that the fossil fuel energy used by anthropogenic activities promoting soot is the crucial reason for high-refractory PBC. We estimated that the Yangtze River transported 0.15–0.23 Tg of soot and 0.15–0.25 Tg of char to the ocean annually, and the export of large higher refractory PBC to the ocean can form a long-term sink and prolong the residence time of terrigenous carbonThis study was supported by grants from the National Natural Science Foundation of China (nos. 42277214, 42207256, and 41971286), major programs of the National Social Science Foundation of China (grant nos. 22&ZD136), the Special Science and Technology Innovation Program for Carbon Peak and Carbon Neutralization of Jiangsu Province (grant no. BE2022612)Peer reviewe

Some recent advances in ab initio calculations of nonradiative decay rates of point defects in semiconductors

Abstract In this short review, we discuss a few recent advances in calculating the nonradiative decay rates for point defects in semiconductors. We briefly review the debates and connections of using different formalisms to calculate the multi-phonon processes. We connect Dr. Huang’s formula with Marcus theory formula in the high temperature limit, and point out that Huang’s formula provide an analytical expression for the phonon induced electron coupling constant in the Marcus theory formula. We also discussed the validity of 1D formula in dealing with the electron transition processes, and practical ways to correct the anharmonic effects.</jats:p