151,917 research outputs found

    Crumpling wires in two dimensions

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    An energy-minimal simulation is proposed to study the patterns and mechanical properties of elastically crumpled wires in two dimensions. We varied the bending rigidity and stretching modulus to measure the energy allocation, size-mass exponent, and the stiffness exponent. The mass exponent is shown to be universal at value DM=1.33D_{M}=1.33. We also found that the stiffness exponent α=0.25\alpha =-0.25 is universal, but varies with the plasticity parameters ss and θp\theta_{p}. These numerical findings agree excellently with the experimental results

    Modulation of sterol homeostasis by the Cdc42p effectors Cla4p and Ste20p in the yeast Saccharomyces cerevisiae

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    This article is available open access through the publisher’s website at the link below. Copyright @ 2009 The Authors.The conserved Rho-type GTPase Cdc42p is a key regulator of signal transduction and polarity in eukaryotic cells. In the yeast Saccharomyces cerevisiae, Cdc42p promotes polarized growth through the p21-activated kinases Ste20p and Cla4p. Previously, we demonstrated that Ste20p forms a complex with Erg4p, Cbr1p and Ncp1p, which all catalyze important steps in sterol biosynthesis. CLA4 interacts genetically with ERG4 and NCP1. Furthermore, Erg4p, Ncp1p and Cbr1p play important roles in cell polarization during vegetative growth, mating and filamentation. As Ste20p and Cla4p are involved in these processes it seems likely that sterol biosynthetic enzymes and p21-activated kinases act in related pathways. Here, we demonstrate that the deletion of either STE20 or CLA4 results in increased levels of sterols. In addition, higher concentrations of steryl esters, the storage form of sterols, were observed in cla4Δ cells. CLA4 expression from a multicopy plasmid reduces enzyme activity of Are2p, the major steryl ester synthase, under aerobic conditions. Altogether, our data suggest that Ste20p and Cla4p may function as negative modulators of sterol biosynthesis. Moreover, Cla4p has a negative effect on steryl ester formation. As sterol homeostasis is crucial for cell polarization, Ste20p and Cla4p may regulate cell polarity in part through the modulation of sterol homeostasis.Deutsche Forschungsgemeinschaft and the Austrian FWF

    Direction discriminating hearing aid system

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    A visual display was developed for people with substantial hearing loss in either one or both ears. The system consists of three discreet units; an eyeglass assembly for the visual display of the origin or direction of sounds; a stationary general purpose noise alarm; and a noise seeker wand

    Thermalization and temperature distribution in a driven ion chain

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    We study thermalization and non-equilibrium dynamics in a dissipative quantum many-body system -- a chain of ions with two points of the chain driven by thermal bath under different temperature. Instead of a simple linear temperature gradient as one expects from the classical heat diffusion process, the temperature distribution in the ion chain shows surprisingly rich patterns, which depend on the ion coupling rate to the bath, the location of the driven ions, and the dissipation rates of the other ions in the chain. Through simulation of the temperature evolution, we show that these unusual temperature distribution patterns in the ion chain can be quantitatively tested in experiments within a realistic time scale.Comment: 5 pages, 5 figure

    A large-scale one-way quantum computer in an array of coupled cavities

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    We propose an efficient method to realize a large-scale one-way quantum computer in a two-dimensional (2D) array of coupled cavities, based on coherent displacements of an arbitrary state of cavity fields in a closed phase space. Due to the nontrivial geometric phase shifts accumulating only between the qubits in nearest-neighbor cavities, a large-scale 2D cluster state can be created within a short time. We discuss the feasibility of our method for scale solid-state quantum computationComment: 5 pages, 3 figure

    Eccentricity Evolution of Extrasolar Multiple Planetary Systems due to the Depletion of Nascent Protostellar Disks

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    Most extrasolar planets are observed to have eccentricities much larger than those in the solar system. Some of these planets have sibling planets, with comparable masses, orbiting around the same host stars. In these multiple planetary systems, eccentricity is modulated by the planets' mutual secular interaction as a consequence of angular momentum exchange between them. For mature planets, the eigenfrequencies of this modulation are determined by their mass and semi-major axis ratios. But, prior to the disk depletion, self gravity of the planets' nascent disks dominates the precession eigenfrequencies. We examine here the initial evolution of young planets' eccentricity due to the apsidal libration or circulation induced by both the secular interaction between them and the self gravity of their nascent disks. We show that as the latter effect declines adiabatically with disk depletion, the modulation amplitude of the planets' relative phase of periapse is approximately invariant despite the time-asymmetrical exchange of angular momentum between planets. However, as the young planets' orbits pass through a state of secular resonance, their mean eccentricities undergo systematic quantitative changes. For applications, we analyze the eccentricity evolution of planets around Upsilon Andromedae and HD168443 during the epoch of protostellar disk depletion. We find that the disk depletion can change the planets' eccentricity ratio. However, the relatively large amplitude of the planets' eccentricity cannot be excited if all the planets had small initial eccentricities.Comment: 50 pages including 11 figures, submitted to Ap
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