'Ticking the Ethnic Box' : The experiences of minority ethnic young people in rural communities

Peer reviewedPublisher PD

Ticking the ethnic box : minority young in rural communities

Peer reviewedPublisher PD

Avaliação dos constituintes voláteis, exsudação de resina e ocorrência de galhas em Protium aracouchini (Aubl.) Marchand

Protium aracouchini (Aubl.) Marchand [sin Icica aracouchini Aubl.], which occurs in the Adolpho Ducke Forest Reserve, in the Brazilian Amazon, was evaluated for the presence of galls, for resin exudation and the composition of the essential oils from the aerial parts and the resin. The experiment to stimulate the exudation of resin from the trunk was conducted using a 2-chloroethylphosphonic acid solution. The resin produced after 40 days and the aerial parts had their essential oils extracted in a Clevenger apparatus and the volatile chemical constituents were analyzed using GC/MS. The non-oxygenated sesquiterpenes α-copaene (21.15%) and α-gurjunene (13.69%), in addition to the oxygenated sesquiterpene spathulenol (10.32%), were detected as the majority constituents of the essential oil of the leaves, and a concentration similar to that of α-gurjunene was found in the branches (13.28%). The resin essential oil showed a high concentration of hydrocarbon monoterpenes (76.49%) with a predominance of α-pinene (17.57%) and limonene (46.11%). Four gall morphotypes were found associated with this species. The present study reports for the first time information on the volatile constituents and the resinous potential of P. aracouchini, and registers the morphotypes of the galls that help in the taxonomy of the species.Protium aracouchini (Aubl.) Marchand [sin Icica aracouchini Aubl.] ocorrente na Reserva Florestal Adolpho Ducke, Amazônia Brasileira foi avaliada quanto a presença de galhas, a exsudação de resina e composição dos óleos essenciais das partes aéreas e resina. O experimento para estímulo à exsudação de resina no tronco foi conduzida utilizando-se uma solução de ácido 2-cloroetilfosfônico. A resina produzida após 40 dias e as partes aéreas foram submetidas à extração de óleos essenciais em Clevenger e os constituintes químicos voláteis analisados por CG/EM. Os sesquiterpenos não oxigenados, α-copaeno (21,15%) e α-gurjuneno (13,69%), além do sesquiterpeno oxigenado espatulenol (10,32%), foram detectados como os constituintes majoritários no óleo essencial das folhas, concentração similar ao α-gurjuneno foi encontrada nos galhos (13,28%). O óleo essencial da resina mostrou alta concentração de hidrocarbonetos monoterpênicos (76,49%) predominando o α-pineno (17,57%) e o limoneno (46,11%). Quatro morfotipos de galhas foram encontrados associadas a esta espécie. O presente estudo relata, pela primeira vez, o conhecimento sobre os constituintes voláteis e o potencial resinífero de P. aracouchini bem como registra os morfotipos das galhas que auxiliam na taxonomia da espécie

Hemophagocytic lymphohistiocytosis of indeterminate cause: a fatal adult case

Hemophagocytic lymphohistiocytosis (HLH) is an uncommon life-threatening disorder characterized by wide spread non-neoplastic proliferation and inappropriate activation of mature macrophages resulting in hypercytokinemia.This uncontrollable and ineffective systemic immune response causes fever, hepatosplenomegaly, cytopenias and subsequently multiorgan failure. The authors report a case of a 41-year-old male patient with a 30-day history of weight loss, fever, icterus, hepatomegaly, and cytopenias. The diagnosticworkup disclosed hypertriglyceridemia, hypofibrinogenemia, and elevated ferritin. Bone marrow examination and clinical course raised the suspicion of HLH and treatment was started with high-dose corticosteroids and immune globulin. The patient underwent multi-organ failure and expired after 58 days ofhospitalization. The autopsy finding included massive bone marrow infiltration by non-neoplastic histiocytes, many of them showing hemophagocytosis, which immunohistochemical study revealed diffuse CD68-positive histiocytes, which were negative for S100 protein. Hemophagocytosis was also observedin the lungs, lymph nodes and liver. The immediate cause of death was attributed to a massive intestinal bleeding due to extensive ischemic necrosis at the duodenum/jejunal transition area.nul

On fusion algebra of chiral SU(N)kSU(N)_{k} models

We discuss some algebraic setting of chiral $SU(N)_{k}$ models in terms of the statistical dimensions of their fields. In particular, the conformal dimensions and the central charge of the chiral $SU(N)_{k}$ models are calculated from their braid matrices. Futhermore, at level K=2, we present the characteristic polynomials of their fusion matrices in a factored form.Comment: 11 pages, ioplpp

A seleção do modo verbal em orações completivas do português

a seleção do modo verbal, a despeito das inúmeras pesquisas sobre o tema, permanece um desafio à descrição linguística, especialmente, em contextos em que o indicativo alterna com o subjuntivo. Neste trabalho, analisam-se ocorrências de orações completivas introduzidas por que, retiradas de um corpus do português culto falado em Fortaleza, com o fim de investigar os fatores sintático-semânticos que podem influenciar a escolha do modo da subordinada. Baseados em Bybee e Terrell (1990) e  Pottier (1992), faz-se uma pesquisa quanti-qualitativa, que revelou serem as variáveis valor semântico e tipo de oração as mais significantes estatisticamente. Quanto ao valor semântico, o indicativo predomina em todas as classes, com exceção do valor de desejo/intenção, em que o subjuntivo é o mais frequente tanto na direção da função para a forma (81,3% - 26/32), quando da forma para a função (38,8% - 26/67). Quanto ao tipo de oração, há maior frequência de subjuntivo nas orações objetivas indiretas (70%). A predominância do indicativo sobre o subjuntivo parece se dever à tendência de não codificação gramatical da subjetividade em contextos em que o sentido subjetivo é previsível, como resultado da atuação do princípio da economia

Citrus: A Perspective for Developing Phytomedicines for Neurodegenerative Diseases

The antioxidant and anti-inflammatory properties of Citrus flavonoids can play a key role in their activity against several degenerative diseases and particularly brain diseases. In Brazil promising studies deposited in the patents “pharmaceutical formulation” form was obtained from the inclusion of Citrus sinensis L. (orange) essential oil with β-cyclodextrin and Citrus limon (lemon) compounds and their applications in therapy of Alzheimer’s disease. In this chapter, we report activities of active compounds present in the genus Citrus, which include antioxidant, anti-inflammatory, anxiolytic, insecticidal, and anticholinesterase activities. These activities are associated with some neurodegenerative diseases such as Alzheimer’s disease (AD). Pharmaceutical formulations containing such compounds (for example, inhibitors such as acetylcholinesterase (AChE) of C. limon (5,8-dimethoxy-psoralen and 5,7-dimethoxycumarin) and essential oil from C. sinensis oils are reported in this chapter. These results indicate that the effects of the essential oil and substances of Citrus species are very interesting for further isolation of AChE inhibitors that can be used in the formulation of natural products for neurodegenerative diseases

Acute erythroid leukemia: autopsy report of a rare disease

Acute erythroid leukemia (AEL) is a rare subtype of acute myeloid leukemia(AML), characterized by predominant erythroid proliferation. The 2008 WorldHealth Organization (WHO) classification of AML defined two AEL subtypes:erythroleukaemia (EL), in which erythroid precursors account for 50% or moreof all nucleated bone marrow cells and myeloblasts account for 20% or more ofthe nonerythroid cell population; and pure erythroid leukemia (PEL), in whicherythroid precursors account for 80% or more of all nucleated bone marrowcells. We report the case of an elderly female patient with wasting syndromeand pancytopenia without evidence of blasts in peripheral blood. A diagnosisof PEL was established on the basis of bone marrow biopsy findings. Thepatient died on postadmission day 20, and an autopsy was performed. Wereclassified the disease as EL on the basis of the autopsy findings, whichincluded myeloblasts accounting for more than 20% of the nonerythroid cellsin the bone marrow, as well as leukemic infiltration and myeloid metaplasia insolid organs, such as the liver, spleen, kidneys, adrenal glands, and abdominallymph nodes. A rare disease, AEL accounts for less than 5% of all AMLs and ispractically a diagnosis of exclusion. Autopsy reports of AEL are extremely rarein the literature. We demonstrate that in the case reported here, leukemia cellstended to infiltrate solid organs with myeloid metaplasia. Our findings alsoshow that a larger neoplastic bone marrow sample is crucial to the correctdiagnosis of EL, which is based on morphological and quantitative criteria

Life-threatening acute acalculous cholecystitis in a patient with renal cell carcinoma treated by sunitinib: a case report

<p>Abstract</p> <p>Introduction</p> <p>Sunitinib, an oral multitargeted tyrosine kinase inhibitor, is widely used in the treatment of renal cell carcinoma and gastrointestinal stromal tumor and has had a variety of adverse events. However, sunitinib-related acute cholecystitis has been reported in only two patients with gastrointestinal stromal tumor and renal cell carcinoma (clear cell subtype).</p> <p>Case presentation</p> <p>A 75-year-old Japanese woman with a right sided abdominal swelling was referred to our hospital. Computed tomography (CT) showed a hypervascular bulky tumor in her right kidney, suggesting right renal cell carcinoma in clinical T4N0M0. Although sunitinib therapy was started as neoadjuvant chemotherapy, during the fourth week of the first cycle, she developed acute acalculous cholecystitis and disseminated intravascular coagulation associated with sunitinib. Sunitinib therapy was discontinued immediately and she recovered after subsequent treatment with antibiotics and gabexate mesilate followed by percutaneous cholecystostomy. Cholecystectomy and right radical nephrectomy were performed and pathological examination showed that her renal tumor was a chromophobe renal cell carcinoma (pT2) with necrosis. Inflammation and ischemia were observed in the gallbladder wall, which was compatible with acute acalculous cholecystitis. There has been no evidence of disease recurrence for more than six months.</p> <p>Conclusion</p> <p>We described the third case of sunitinib-related acute cholecystitis in a patient with chromophobe renal cell carcinoma. Attention is required to sunitinib-related acute cholecystitis which, while uncommon, could be life-threatening.</p

CONHECIMENTO E COMPORTAMENTOS DE PESSOAS SURDAS EM RELAÇÃO ÀS INFECÇÕES SEXUALMENTE TRANSMISSÍVEIS

Objetivo: identificar o conhecimento e os comportamentos de risco para infecções sexualmente transmissíveis em pessoas surdas. Método: estudo transversal realizado com 110 pessoas surdas residentes no noroeste do Paraná, selecionadas com a técnica da bola de neve. Os dados foram coletados mediante instrumento estruturado e submetidos à análise estatística descritiva e inferencial (uso de regressão logística múltipla). Resultados: a maioria possuía pouca informação sobre as formas de transmissão e prevenção das infecções sexualmente transmissíveis (menos de 40% de acertos em relação a hepatite, a gonorreia e a sífilis, sendo que 20,9% já teve sintoma de infecção sexualmente transmissível). Nove dos 26 que tiveram relação sexual casual não usaram preservativo. Pessoas bilíngues bimodal apresentaram mais chance de conhecer formas de transmissão e prevenção das infecções sexualmente transmissíveis e ter comportamentos sexuais seguros. Conclusão: os surdos em estudo demonstraram pouco conhecimento sobre as formas de transmissão e prevenção de infecções sexualmente transmissíveis, o que constitui desafio para os profissionais de saúde. Descritores: Doenças sexualmente transmissíveis. Surdez. Barreiras de comunicação. Acesso à informação. Conhecimento