Inhibitory effect of some phytochemicals in the growth of yeasts potentially causing opportunistic infections

Opportunistic infections caused by yeasts have been characterized as emerging diseases all over the world and this has caused the search for new products capable of inhibiting the survival of their etiological agents. In this study the sensitivity of some yeast potentially causing infections to alpha-pinene, beta-pinene, citral and eugenol was evaluated. All phytochemicals showed inhibitory action on the assayed yeast strains: Candida. albicans, C. tropicalis, C. guilliermondii, C. stellatoidea, C. krusei, C. parapsilosis and Cryptococcus neoformans, presenting their MIC values in the range of 1 and 4%. The phytochemicals presented effectiveness to provide high fungicide effect in a short time. These data support the possible use of some phytochemicals as useful tools to control the occurrence of opportunistic infections caused by yeasts.Infecções oportunistas causadas por leveduras têm sido caracterizadas como doenças emergentes em todo o mundo e este fenômeno tem levado ao desenvolvimento de novos produtos capazes de inibir a sobrevivência de seus agentes etiológicos. Este estudo avaliou o perfil de sensibilidade de leveduras potencialmente causadoras de infecções oportunistas frente aos fitoconstituintes alfa-pineno, beta-pineno, citral e eugenol. Todos os fitoconstituintes mostraram ação inibitória sobre as leveduras ensaiadas, as quais foram Candida albicans, C. tropicalis, C. guilliermondii, C. stellatoidea, C. krusei, C. parapsilosis e Cryptococcus neoformans, tendo valores de CIM oscilando entre 1 e 4%. Os fitoconstituintes mostraram eficácia para provocar um alto efeito fungicida em curto tempo de ação. Estes dados subsidiam o possível uso de alguns fitoconstituintes como ferramentas úteis para controlar a ocorrência de infecções oportunistas causadas por leveduras

Review of the plants with anti-inflammatory activity studied in Brazil

The inflammatory reaction is a response of the organism against an injury and it involves the action of complex events and mediators through of the blood vessels. The present work is a literature survey of the extracts of plants with anti-inflammatory activity studied in Brazil. The review refers to 75 plants with their families, parts used, type of extract used, bioassay models and their activity