Novel OTEC Cycle Using Efficiency Enhancer

The ocean thermal energy conversion (OTEC) plant is designed to improve the efficiency of the existing plants. Various researches are being conducted to increase the plant’s efficiency and output with the use of an enhancer, and studies for performance improvement are also in progress from the Kalina and Uehara cycles to ejector pump OTEC (EP-OTEC). Their performance can be improved by increasing the evaporation pressure using an unused heat source and reducing the heat consumption using a reheating system and a regenerator. In the case of EP-OTEC, an ejector is installed near the turbine-exit to reduce the pressure and therefore increase the power output. In simulations and experiments conducted in this study, EP-OTEC showed 38% efficiency improvement from the basic cycle, which is due to the power output volume increase. The optimum ratio was derived by adjusting the pressure ratio. The demonstration plant to be developed in the future is expected to be applied to the high-efficiency OTEC demonstration plant with improved performance, and new technologies will be continuously developed considering economics and commercial viability

Monitoring daily evapotranspiration in Northeast Asia using MODIS and a regional Land Data Assimilation System

We applied an approach for daily estimation and monitoring of evapotranspiration (ET) over the Northeast Asia monsoon region using satellite remote sensing observations from the Moderate Resolution Imaging Spectroradiometer (MODIS). Frequent cloud cover results in a substantial loss of remote sensing information, limiting the capability of continuous ET monitoring for the monsoon region. Accordingly, we applied and evaluated a stand-alone MODIS ET algorithm for representative regional ecosystem types and an alternative algorithm to facilitate continuous regional ET estimates using surface meteorological inputs from the Korea Land Data Assimilation System (KLDAS) in addition to MODIS land products. The resulting ET calculations showed generally favorable agreement (root-mean-square error  \u3c 1.3 mm d−1) with respect to in situ measurements from eight regional flux tower sites. The estimated mean annual ET for 3 years (2006 to 2008) was approximately 362.0 ± 161.5 mm yr−1 over the Northeast Asia domain. In general, the MODIS and KLDAS-based ET (MODIS-KLDAS ET) results showed favorable performance when compared to tower observations, though the results were overestimated for a forest site by approximately 39.5% and underestimated for a cropland site in South Korea by 0.8%. The MODIS-KLDAS ET data were generally underestimated relative to the MODIS (MOD16) operational global terrestrial ET product for various biome types, excluding cropland; however, MODIS-KLDAS ET showed better agreement than MOD16 ET for forest and cropland sites in South Korea. Our results indicate that MODIS ET estimates are feasible but are limited by satellite optical-infrared remote sensing constraints over cloudy regions, whereas alternative ET estimates using continuous meteorological inputs from operational regional climate systems (e.g., KLDAS) provide accurate ET results and continuous monitoring capability under all-sky conditions

Dynamic Simulation of System Performance Change by PID Automatic Control of Ocean Thermal Energy Conversion

Near infinite seawater thermal energy, which is considered as an alternative to energy shortage, is expected to be available to 98 countries around the world. Currently, a demonstration plant is being built using closed MW class ocean thermal energy conversion (OTEC). In order to stabilize the operation of the OTEC, automation through a PID control is required. To construct the control system, the control logic is constructed, the algorithm is selected, and each control value is derived. In this paper, we established an optimal control system of a closed OTEC, which is to be demonstrated in Kiribati through simulation, to compare the operating characteristics and to build a system that maintains a superheat of 1 °C or more according to seawater temperature changes. The conditions applied to the simulation were the surface seawater temperature of 31 °C and the deep seawater temperature of 5.5 °C, and the changes of turbine output, flow rate, required power, and evaporation pressure of the refrigerant pump were compared as the temperature difference gradually decreased. As a result of comparing the RPM control according to the selected PID control value, it was confirmed that an error rate of 0.01% was shown in the temperature difference condition of 21.5 °C. In addition, the average superheat degree decreased as the temperature difference decreased, and after about 6000 s and a temperature decrease to 24 °C or less, the average superheat degree was maintained while maintaining the superheat degree of 1.7 °C on average

Performance Analysis Based on Fuel Valve Train Control Optimization of Ammonia-Fuel Ships

In order to reduce carbon emissions, which are currently a problem in the shipping and offshore plant sectors, the international community is strengthening regulations such as the Energy Efficiency Design Index (EEDI) and Energy Efficiency Existing Ship Index (EEXI). To cope with this, eco-friendly fuel propulsion technology is being developed, and the development of an ammonia fuel supply system is in progress. Among them, fuel valve train (FVT) technology was researched for the final supply and cutoff of fuel and purging through nitrogen for ammonia engines. In this paper, we analyzed the change in ammonia supply due to FVT opening and the change in nitrogen supply due to closure. In addition, a plan to minimize risk factors was presented by applying a control method to remove residual fuel in FVT. According to the presented FVT model, the difference in the flow rate of supplied fuel was as much as 17.8 kg/s. Additionally, by opening the gas bleed valve at intervals during the closing process and purging about 0.28 kg of nitrogen, the internal fuel could be completely discharged. This is expected to have an impact on improving the marine environment through the application of eco-friendly fuels and the development of fuel supply system technology

Performance Evaluation of Control Compatibility for an OTEC Pump Shutdown Condition

South Korea is currently in the preparatory stage of commercializing an ocean thermal energy conversion (OTEC) system, as the demonstration of a 1 MW scale OTEC system has been accomplished. However, the commercialization of OTEC requires the establishment of a control system for various environmental changes. Therefore, pre-emptive identification of the system’s risk factors and the process of analyzing the impact of the system, building control items, and optimizing control are necessary. This study aims to establish and analyze an optimized control system for MW-scale OTEC risk factors, such as the shutdown of seawater or refrigerant pumps. The selected OTEC system was designed for 1070 kW class facilities, with a 36.6% portion of total electricity usage by the seawater pump and refrigerant pump. As a result, an on/off control system was adopted in order to eliminate the risk factors. By adjusting this option, dry operation of the refrigerant pump, water hammering, and liquid inflow into the turbine were successfully prevented. To be more specific, the initial system was to be shut down due to a sharp decrease in power at the point where the deep seawater flow rate was 538 kg/s (35.7% of max flow rate) and the surface seawater flow rate was 715 kg/s (38.4% of max flow rate). This situation was improved by adopting parallel operation of seawater pumps and on/off control, thereby leading to a more stabilized operation by maintaining a flow rate of over 1864 kg/s for surface seawater and 1507 kg/s for deep seawater. Moreover, it was confirmed that the flow rate of the pump was reduced by 1.89 kg/s per second in the process of pump shutdown during a single operation mode of the refrigerant pump. Parallel operation made it possible to maintain 60.2% of the output by increasing the power of the second pump’s flow rate in the event of the first pump shutting down. The final seawater temperature differential power generation model derived from this study consists of two refrigerant pumps and two surface seawater and deep seawater pumps in order to prevent system shutdown caused by a single pump failure. The final design was reflected in the final delivery to Kiribati, which is located near the equator

A Case of Gingival Candidiasis with Bone Destruction on Gastric Cancer Patient Receiving Cytotoxic Chemotherapy

We herein report a case of gingival candidiasis in an advanced gastric cancer patient while receiving palliative cytotoxic chemotherapy. A 46-year-old male patient admitted to our hospital for known advanced gastric cancer with newly developed multiple liver metastases. While receiving 2nd line cytotoxic chemotherapy with 5FU, leucovorin, and paclitxel, he complained of gingival swelling accompanied by pain and whitish plaque. Due to lack of response to the conservative oral care, incisional biopsy of gingiva was done and the pathology confirmed gingival candidiasis. Although the lesion healed apparently after two-week antifungal therapy, pain as well as bony destruction remains. By presenting this case report, we intend to emphasize the immunocompromising effect of cancer while being on systemic chemotherapy

Synthesis and structure–activity relationship study of saponin-based membrane fusion inhibitors against SARS-CoV-2

© 2022 Elsevier Inc.We previously discovered that triterpenoid saponin platycodin D inhibits the SARS-CoV-2 entry to the host cell. Herein, we synthesized various saponin derivatives and established a structure–activity relationship of saponin-based antiviral agents against SARS-CoV-2. We discovered that the C3-glucose, the C28-oligosaccharide moiety that consist of (→3)-β-D-Xyl-(1 → 4)-α-L-Rham-(1 → 2)-β-D-Ara-(1 → ) as the last three sugar units, and the C16-hydroxyl group were critical components of saponin-based coronavirus cell entry inhibitors. These findings enabled us to develop minimal saponin-based antiviral agents that are equipotent to the originally discovered platycodin D. We found that our saponin-based antiviral agents inhibited both the endosomal and transmembrane protease serine 2-mediated cell surface viral entries. Cell fusion assay experiment revealed that our newly developed compounds inhibit the SARS-CoV-2 entry by blocking the fusion between the viral and host cell membranes. The effectiveness of the newly developed antiviral agents over various SARS-CoV-2 variants hints at the broad-spectrum antiviral efficacy of saponin-based therapeutics against future coronavirus variants.11Nsciescopu