3,184 research outputs found
Hubble Frontier Field Free-form Mass Mapping of the Massive Multiple-merging Cluster MACSJ0717.5+3745
published_or_final_versio
Hubble Frontier Field Free-form Mass Mapping of the Massive Multiple-merging Cluster MACSJ0717.5+3745
published_or_final_versio
Potential impact of a maternal vaccine for RSV: a mathematical modelling study
Respiratory syncytial virus (RSV) is a major cause of respiratory morbidity and one of the main causes of hospitalisation in young children. While there is currently no licensed vaccine for RSV, a vaccine candidate for pregnant women is undergoing phase 3 trials. We developed a compartmental age-structured model for RSV transmission, validated using linked laboratory-confirmed RSV hospitalisation records for metropolitan Western Australia. We adapted the model to incorporate a maternal RSV vaccine, and estimated the expected reduction in RSV hospitalisations arising from such a program. The introduction of a vaccine was estimated to reduce RSV hospitalisations in Western Australia by 6-37% for 0-2month old children, and 30-46% for 3-5month old children, for a range of vaccine effectiveness levels. Our model shows that, provided a vaccine is demonstrated to extend protection against RSV disease beyond the first three months of life, a policy using a maternal RSV vaccine could be effective in reducing RSV hospitalisations in children up to six months of age, meeting the objective of a maternal vaccine in delaying an infant's first RSV infection to an age at which severe disease is less likely
A importância dos valores numa gestão de recursos humanos socialmente responsável - estudo de caso numa empresa seguradora angolana
A análise dos valores e a importância dos mesmos na organização e na gestão é o ponto de
partida do tema em abordagem. Pretende-se entender como a observância de valores é
determinante na gestão socialmente responsável. Destacaremos o papel dos modelos de
gestão de recursos humanos e da cultura da organização, onde são criados e veiculados os
valores organizacionais, enfatizando-se a ética e a responsabilidade social.
Nesta Dissertação realizou-se um Estudo de Caso numa grande seguradora angolana, onde
através da análise documental, da observação directa e de entrevistas semi-estruturadas a
informantes-chave foi possÃvel inventariar os valores organizacionais e caracterizar as
principais polÃticas numa perspectiva de gestão de recursos humanos socialmente
responsável; ABSTRACT: The analysis of the values and its importance at organization and management is the starting
point of the theme approach. The aim is to understand how the observance of values is
crucial in the socially responsible management. Highlight the role of models in human
resource management and organizational culture, where they are created and conveyed
organizational values, emphasizing ethics and social responsibility. In this thesis we
performed a case study in a large insurance company of Angola, where through the
document analysis, direct observation and semi-structured interviews with key informants
was possible to make an inventory of organizational values and characterize the main
policies from the perspective of resource management socially responsible human
Orbital superfluidity in the -band of a bipartite optical square lattice
The successful emulation of the Hubbard model in optical lattices has
stimulated world wide efforts to extend their scope to also capture more
complex, incompletely understood scenarios of many-body physics. Unfortunately,
for bosons, Feynmans fundamental "no-node" theorem under very general
circumstances predicts a positive definite ground state wave function with
limited relevance for many-body systems of interest. A promising way around
Feynmans statement is to consider higher bands in optical lattices with more
than one dimension, where the orbital degree of freedom with its intrinsic
anisotropy due to multiple orbital orientations gives rise to a structural
diversity, highly relevant, for example, in the area of strongly correlated
electronic matter. In homogeneous two-dimensional optical lattices, lifetimes
of excited bands on the order of a hundred milliseconds are possible but the
tunneling dynamics appears not to support cross-dimensional coherence. Here we
report the first observation of a superfluid in the -band of a bipartite
optical square lattice with -orbits and -orbits arranged in a
chequerboard pattern. This permits us to establish full cross-dimensional
coherence with a life-time of several ten milliseconds. Depending on a small
adjustable anisotropy of the lattice, we can realize real-valued striped
superfluid order parameters with different orientations or a
complex-valued order parameter, which breaks time reversal
symmetry and resembles the -flux model proposed in the context of high
temperature superconductors. Our experiment opens up the realms of orbital
superfluids to investigations with optical lattice models.Comment: 5 pages, 5 figure
The evolution of peripheral nerve treatment for trigeminal neuralgia - peripheral nerve surgery
Trigeminal neuralgia typically presents with a sudden and severe facial pain.
Although peripheral nerve injection can produce good pain relief in the treatment
of trigeminal neuralgia, their effect may not be permanent. Surgical treatment
has always been an alternative for patients who do not respond well to medical
treatment or, for those who are severely affected by the side effects of anticonvulsants.
Unknown to most young healthcare providers, surgical treatment was
the first line treatment at the turn of the 19th century till 1960s. This review narrates
the evolution of peripheral nerve treatment for trigeminal neuralgia over the last
150 years
The evolution of peripheral nerve treatment for trigeminal neuralgia - peripheral injections
Trigeminal neuralgia presents as a characteristic severe painful condition that
usually afflicts the area(s) innervated by the branches of the facial sensory nerves,
especially the elderly females. The diagnosis can usually be made based solely on
the presenting clinical signs and symptoms. Early literatures had revealed that there
have always been two major means of treatment for trigeminal neuralgia; medical
and surgical. Medical treatments involved systemic intake of various drugs or the
topical applications of many different materials, not forgetting that bleeding and
purging has been tried in the past. The introduction of anti-convulsants during thesecond World War had changed completely the way this painful condition was
treated as this therapy later become the mainstay treatment for trigeminal neuralgia.
Their beneficial effects, however may not be long lasting. This review summarises
the evolution of peripheral nerve injection as a treatment for trigeminal neuralgia
over the last 150 years
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