Confocal micro-XRF/XANES analysis on insects trapped in amber

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Rapid Decline of Follicular Lymphoma-Associated Chylothorax after Low Dose Radiotherapy to Retroperitoneal Lymphoma Localization

Chylothorax is caused by disruption or obstruction of the thoracic duct or its tributaries that results in the leakage of chyle into the pleural space. A number of interventions have been used to treat chylothorax including the treatment of the underlying disease. Lymphoma is found in 70% of cases with nontraumatic malignant aetiology. Although patients usually have advanced lymphoma, supradiaphragmatic disease is not always present. We discuss the case of a 63-year-old woman presenting with progressive respiratory symptoms due to chylothorax. She was diagnosed with a stage IIE retroperitoneal grade 1 follicular lymphoma extending from the coeliac trunk towards the pelvic inlet. Despite thoracocentesis and medium-chain triglycerides (MCT), diet chylothorax reoccurred. After low dose radiotherapy (2×2 Gy) to the abdominal lymphoma there was a marked decrease in lymphadenopathy at the coeliac trunk and a complete regression of the pleural fluid. In this case, radiotherapy was shown to be an effective nontoxic treatment option for lymphoma-associated chylothorax with long-term remission of pleural effusion

A web application for browsing a folk music collection

V diplomski nalogi je predstavljena realizacija spletne aplikacije, ki uporabniku omogoča pregled zbirke ljudske glasbe in iskanje po njej. Razvili smo idejo in jo implementirali v programskem jeziku C#. Uporabili smo ogrodje .NET, arhitekturo MVC5, strežnik MSSQL in iskalni strežnik Elasticsearch. Spletna aplikacija omogoča splošno iskanje ljudske glasbe in iskanje z uporabo filtrov. Za iskanje s filtri smo uporabili Googlov pristop pametnega iskanja. Možen je tudi vnos melodije preko tekstovnega polja ali z uporabo klaviature in tudi iskanje po melodiji. Zaradi uporabe Elasticsearch strežnika sta iskanje in prikaz rezultatov hitra. Omogočen je tudi prikaz notnega zapisa, PDF datotek ter predvajanje avdio in MIDI datotek posameznih pesmi.The thesis presents the realization of a web application that allows the user to review a folk music collection and search within it. We developed the idea and implemented it using C# programming language. We used the .NET framework, MVC5 architecture, MSSQL server and Elasticsearch search server. The Web application provides general searching of folk music and searching with the help of filters. We used Google’s smart search approach for searching with the filters. We can enter a melody in the text field or use the keyboard to search by melody. Searching and displaying of results are fast, due to the use of the Elasticsearch server. The application also shows musical notations, PDF-files and can play audio and MIDI files

Oligorecurrent nodal prostate cancer: radiotherapy quality assurance of the randomized PEACE V-STORM phase II trial.

PURPOSE Aim of this study is to report the results of the radiotherapy quality assurance program of the PEACE V-STORM randomized phase II trial for pelvic nodal oligorecurrent prostate cancer (PCa). MATERIAL AND METHODS A benchmark case (BC) consisting of a postoperative case with 2 nodal recurrences was used for both stereotactic body radiotherapy (SBRT, 30 Gy/3 fx) and whole pelvic radiotherapy (WPRT, 45 Gy/25 fx + SIB boost to 65 Gy). RESULTS BC of 24 centers were analyzed. The overall grading for delineation variation of the 1st BC was rated as 'UV' (Unacceptable Variation) or 'AV' (Acceptable Variation) for 1 and 7 centers for SBRT (33%), and 3 and 8 centers for WPRT (46%), respectively. An inadequate upper limit of the WPRT CTV (n=2), a missing delineation of the prostate bed (n=1), and a missing nodal target volume (n=1 for SBRT and WPRT) constituted the observed 'UV'. With the 2nd BC (n=11), the overall delineation review showed 2 and 8 'AV' for SBRT and WPRT, respectively, with no 'UV'. For the plan review of the 2nd BC, all treatment plans were per protocol for WPRT. SBRT plans showed variability in dose normalization (Median D90% = 30.1 Gy, range 22.9-33.2Gy and 30.6 Gy, range 26.8-34.2Gy for nodes 1 and 2 respectively). CONCLUSIONS Up to 46% of protocol deviations were observed in delineation of WPRT for nodal oligorecurrent PCa, while dosimetric results of SBRT showed the greatest disparities between centers. Repeated BC resulted in an improved adherence to the protocol, translating in an overall acceptable contouring and planning compliance rate among participating centers