Проектирование основного оборудования для цеха перекачки и подготовки нефти

В магистерской диссертации рассчитано основное оборудование, применяемое при подготовке нефти на промыслах. Произведены технологический, конструктивный и механический расчёты оборудования. Так же предложено применение гидроциклонных систем для очистки подтоварной воды от механических примесей и нефтепродуктов.In master's thesis, the basic equipment used in the preparation of oil in the fields is calculated. Technological, constructive and mechanical calculations of equipment have been made. It is also proposed the use of hydrocyclone systems for cleaning of bottom water from mechanical impurities and petroleum products

Photocatalytic generation of hydrogen using iron-containing metal-ceramic composites with simultaneous degradation of organic compounds

The phase composition of composites was investigated, which were received by nitriding the ferroboron and ferrosilicoaluminium by the SHS method and modified with additives of schungite and titanium. Photocatalytic activity of composites in combined processes of hydrogen generation and degradation of organic substances was investigated. The activity of composites is related to the presence of a phase of metallic iron in their composition, concentration in the system of activator reagents (Н[2]О[2], Н[2]С[2]О[4]), and also with the presence of high energy-gap semiconductor in the composite matrix

Експрес-аналіз ефективності формування вертикально інтегрованих структур

Аналізуються переваги створення вертикально інтегрованих структур. Пропонується методика експрес-аналізу ефективності створення вертикально інтегрованих структур. Advantages of creation of the vertically integrated structures are analyzed. A method is offered express - analysis of efficiency of creation of the vertically integrated structures

Влияние неустановившегося режима эксплуатации на снижение коэффициента продуктивности скважин с трещинами гидроразрыва пласта

В данной выпускной квалификационной работе было исследовано влияние неустановившегося режима течения на количественное снижение коэффициента продуктивности скважин с гидроразрывом пласта. Анализ, проводимый в рамках данной работы показал, что длительность выхода на установившийся режим может достигать несколько месяцев, в течение которых продуктивность скважин с трещинами ГРП может снижаться более чем в два раза. В ходе выполнения проекта была подобрана аналитическая модель расчета снижения коэффициента продуктивности, основанная на геометрии трещины, которая имеет меньшую погрешность по сравнению с существующей формой расчета технологических показателей ГТМ и может использоваться на практике для прогнозирования геолого-технических мероприятий.In this work the estimation of productivity index decline was made. The analysis showed that the duration of transient period may last for a few months. During this period productivity index decline may be very significant. According to calculations, developed method has shown good matching between estimated and actual productivity index values. As it was estimated, this algorithm allows making prediction and forecasting of well behavior and accurate business planning

Proteomic-biostatistic integrated approach for finding the underlying molecular determinants of hypertension in human plasma

Despite advancements in lowering blood pressure, the best approach to lower it remains controversial because of the lack of information on the molecular basis of hypertension. We, therefore, performed plasma proteomics of plasma from patients with hypertension to identify molecular determinants detectable in these subjects but not in controls and vice versa. Plasma samples from hypertensive subjects (cases; n=118) and controls (n=85) from the InGenious HyperCare cohort were used for this study and performed mass spectrometric analysis. Using biostatistical methods, plasma peptides specific for hypertension were identified, and a model was developed using least absolute shrinkage and selection operator logistic regression. The underlying peptides were identified and sequenced off-line using matrix-assisted laser desorption ionization orbitrap mass spectrometry. By comparison of the molecular composition of the plasma samples, 27 molecular determinants were identified differently expressed in cases from controls. Seventy percent of the molecular determinants selected were found to occur less likely in hypertensive patients. In cross-validation, the overall R(2) was 0.434, and the area under the curve was 0.891 with 95% confidence interval 0.8482 to 0.9349, P<0.0001. The mean values of the cross-validated proteomic score of normotensive and hypertensive patients were found to be -2.007±0.3568 and 3.383±0.2643, respectively, P<0.0001. The molecular determinants were successfully identified, and the proteomic model developed shows an excellent discriminatory ability between hypertensives and normotensives. The identified molecular determinants may be the starting point for further studies to clarify the molecular causes of hypertension

Технология ликвидации аварийного разлива нефти в болотистой местности

Объектом исследования является месторождение, болота Томской области, почвы и растительность загрязненных территорий, а так же технологии по рекультивации нефтезагрязненных болотных почв, вследствие аварии на межпромысловом нефтепроводе. Цель работы – Анализ технологии и ликвидации аварийного разлива нефти на межпромысловом нефтепроводе. В процессе исследования проводились расчеты по определению ущерба окружающей природной среде при аварии на промысловом нефтепроводе.The object of the study is a deposit, marshes of the Tomsk region, soils and vegetation of contaminated areas, as well as technologies for reclamation of oil-contaminated bog soils, as a result of an accident at an inter-oil pipeline. The purpose of the work is to analyze the technology and eliminate the oil spill on the inter-pipeline oil pipeline. In the course of the study, calculations were carried out to determine the damage to the natural environment in the event of an oil pipeline accident

Методика использования виртуальной среды SolidWorks Simulation для формирования компетенций будущих инженеров

Формирование способности ассоциировать напряженно-деформированное состояние конструкций и моделей С

Molecular Ultrasound Imaging of Junctional Adhesion Molecule A Depicts Acute Alterations in Blood Flow and Early Endothelial Dysregulation

Objective: The junctional adhesion molecule A (JAM-A) is physiologically located in interendothelial tight junctions and focally redistributes to the luminal surface of blood vessels under abnormal shear and flow conditions accompanying atherosclerotic lesion development. Therefore, JAM-A was evaluated as a target for molecularly targeted ultrasound imaging of transient endothelial dysfunction under acute blood flow variations. Approach and Results: Flow-dependent endothelial dysfunction was induced in apolipoprotein E-deficient mice (n=43) by carotid partial ligation. JAM-A expression was investigated by molecular ultrasound using antibody-targeted poly(n-butyl cyanoacrylate) microbubbles and validated with immunofluorescence. Flow disturbance and arterial remodeling were assessed using functional ultrasound. Partial ligation led to an immediate drop in perfusion at the ligated side and a direct compensatory increase at the contralateral side. This was accompanied by a strongly increased JAM-A expression and JAM-A-targeted microbubbles binding at the partially ligated side and by a moderate and temporary increase in the contralateral artery (approximate to 14x [P<0.001] and approximate to 5x [P<0.001] higher than control, respectively), both peaking after 2 weeks. Subsequently, although JAM-A expression and JAM-A-targeted microbubbles binding persisted at a higher level at the partially ligated side, it completely normalized within 4 weeks at the contralateral side. Conclusions: Temporary blood flow variations induce endothelial rearrangement of JAM-A, which can be visualized using JAM-A-targeted microbubbles. Thus, JAM-A may be considered as a marker of acute endothelial activation and dysfunction. Its imaging may facilitate the early detection of cardiovascular risk areas, and it enables the therapeutic prevention of their progression toward an irreversible pathological state