Monitoring Water and Energy Cycles at Climate Scale in the Third Pole Environment (CLIMATE-TPE)

A better understanding of the water and energy cycles at climate scale in the Third Pole Environment is essential for assessing and understanding the causes of changes in the cryosphere and hydrosphere in relation to changes of plateau atmosphere in the Asian monsoon system and for predicting the possible changes in water resources in South and East Asia. This paper reports the following results: (1) A platform of in situ observation stations is briefly described for quantifying the interactions in hydrosphere-pedosphere-atmosphere-cryosphere-biosphere over the Tibetan Plateau. (2) A multiyear in situ L-Band microwave radiometry of land surface processes is used to develop a new microwave radiative transfer modeling system. This new system improves the modeling of brightness temperature in both horizontal and vertical polarization. (3) A multiyear (2001–2018) monthly terrestrial actual evapotranspiration and its spatial distribution on the Tibetan Plateau is generated using the surface energy balance system (SEBS) forced by a combination of meteorological and satellite data. (4) A comparison of four large scale soil moisture products to in situ measurements is presented. (5) The trajectory of water vapor transport in the canyon area of Southeast Tibet in different seasons is analyzed, and (6) the vertical water vapor exchange between the upper troposphere and the lower stratosphere in different seasons is presented

Semantic Similarity Detection in Natural Language Documents

Data leak prevention (DLP) solutions monitor and control data flow. Current techniques find data that matches user defined syntactic patterns. Unfortunately, large classes of DLP relevant data are defined by information semantics, rather than data syntax. Syntax refers to data format, whereas semantics refers to data meaning. The class of social security numbers can be adequately expressed using data syntax, whereas a new industrial process can only be adequately described using information semantics. In this paper, we propose methods for extracting and identifying document semantics using training sets of limited size (tens of documents). The first method is based on singular value decomposition, which uses linear algebra to automatically extract semantic features from documents in the training set. The second method is to infer a hidden Markov model (HMM) expressing relations between the features extracted using the singular value method. This HMM can detect documents containing the intellectual property semantic information. A third method views the English language as a probabilistic context-free grammar (PCFG), and extracts semantic information from individual sentences in order to detect documents containing intellectual property. Test results on 5 document sets show the proposed methods give at least 84% true positive and below 22% false positive rates. Our methods are trained with only positive examples, and have lower false positive rates, compared to Latent Dirichlet Allocation (LDA) and Support Vector Machines (SVM)

A model reference adaptive variable impedance control method for robot

As a simple and effective force tracking control method, impedance control is widely used in robot contact operations. The internal control parameters of traditional impedance control are constant and cannot be corrected in real time, which will lead to instability of control system or large force tracking error. Therefore, it is difficult to be applied to the occasions requiring higher force accuracy, such as robotic medical surgery, robotic space operation and so on. To solve this problem, this paper proposes a model reference adaptive variable impedance control method, which can realize force tracking control by adjusting internal impedance control parameters in real time and generating a reference trajectory at the same time. The simulation experiment proves that compared with the traditional impedance control method, this method has faster force tracking speed and smaller force tracking error. It is a better force tracking control method

Comparison of the effects of exercise with chondroitin sulfate on knee osteoarthritis in rabbits

Abstract Background The aim of the study is to compare the effects of exercise therapy with chondroitin sulfate (CS) therapy in an experimental model of osteoarthritis (OA). Methods Twenty-one New Zealand rabbits were randomly divided into four groups: normal group (N group, n = 3); OA control group (C group, n = 6); OA plus medication group (CS group, n = 6); and OA plus exercise group (E group, n = 6). Four weeks after modeling, the rabbits were subjected to exercise (artificial, 30 min/time, 4 times/week) or medicated with CS (2% CS, 0.3 ml/time, once/week) for 4 weeks. Histopathological changes in treated joints were examined after staining. X-ray and scanning electron microscopy was used to evaluate the different therapies by examining the surfaces and joint spaces of the articular cartilage. RT-qPCR was used to assess chondrogenic gene expression including Col2, Col10, mmp-13, il-1β, adamats-5, and acan in the experimental groups. Results Histology showed both treatment groups resulted in cartilage that was in good condition, with increased numbers of chondrocytes, and the results of X-ray and scanning electron microscopy showed the therapeutic effect of exercise therapy is equivalent to CS therapy, surface articular cartilage was flat, and the of cartilage layer was thinning. All treated groups induced the expression of Col10 and Col2 and decreased expression of mmp-13, il-1β, and adamats-5 compared with the control groups. The expression of acan was upregulated in the E group and downregulated in the CS group. Furthermore, expression of Col10 was higher and il-1β was lower in the exercise group compared to that of the CS group. Conclusion These results indicate that exercise has a positive effect on OA compare with CS, and it also supplies reference for the movement mode to improve function

Review of Transport Phenomena and Popular Modelling Approaches in Membrane Distillation

In this paper, the transport phenomena in four common membrane distillation (MD) configurations and three popular modelling approaches are introduced. The mechanism of heat transfer on the feed side of all configurations are the same but are distinctive from each other from the membrane interface to the bulk permeate in each configuration. Based on the features of MD configurations, the mechanisms of mass and heat transfers for four configurations are reviewed together from the bulk feed to the membrane interface on the permeate but reviewed separately from the interface to the bulk permeate. Since the temperature polarisation coefficient cannot be used to quantify the driving force polarisation in Sweeping Gas MD and Vacuum MD, the rate of driving force polarisation is proposed in this paper. The three popular modelling approaches introduced are modelling by conventional methods, computational fluid dynamics (CFD) and response surface methodology (RSM), which are based on classic transport mechanism, computer science and mathematical statistics, respectively. The default assumptions, area for applications, advantages and disadvantages of those modelling approaches are summarised. Assessment and comparison were also conducted based on the review. Since there are only a couple of full-scale plants operating worldwide, the modelling of operational cost of MD was only briefly reviewed. Gaps and future studies were also proposed based on the current research trends, such as the emergence of new membranes, which possess the characteristics of selectivity, anti-wetting, multilayer and incorporation of inorganic particles

Literature Review: Theory and Application of In-Line Inspection Technologies for Oil and Gas Pipeline Girth Weld Defection

Girth weld cracking is one of the main failure modes in oil and gas pipelines; girth weld cracking inspection has great economic and social significance for the intrinsic safety of pipelines. This paper introduces the typical girth weld defects of oil and gas pipelines and the common nondestructive testing methods, and systematically generalizes the progress in the studies on technical principles, signal analysis, defect sizing method and inspection reliability, etc., of magnetic flux leakage (MFL) inspection, liquid ultrasonic inspection, electromagnetic acoustic transducer (EMAT) inspection and remote field eddy current (RFDC) inspection for oil and gas pipeline girth weld defects. Additionally, it introduces the new technologies for composite ultrasonic, laser ultrasonic, and magnetostriction inspection, and provides reference for development and application of oil and gas pipeline girth weld defect in-line inspection technology

Yishen-tongbi decoction inhibits excessive activation of B cells by activating the FcγRIIb/Lyn/SHP-1 pathway and attenuates the inflammatory response in CIA rats

Rheumatoid arthritis (RA) is a chronic autoimmune disease. Strong evidence supports that excessive activation of B cells plays a critical role in the pathogenesis of RA. Fc gamma receptor b (FcγRIIb) is the B cell inhibitory receptor and inhibits BCR (B cell receptor) signalling in part by selectively dephosphorylating CD19 which is considered a co-receptor for BCR and is essential for B cell activation. Our previous study demonstrated that a FcγRIIb I232T polymorphism presented a strong genetic link to RA and may lead to the excessive activation of B cells. Therefore, novel therapeutic strategies and drugs that can effectively inhibit the excessive activation of B cells by regulating the FcγRIIb are necessary for the treatment of RA. Therefore, we used Burkitt’s lymphoma ST486 human B cells (lacking endogenous FcγRIIb) transfected with the 232Thr loss-of-function mutant to construct a FcγRIIb mutant cell line (ST486), and we demonstrated that YSTB treatment not only reduced proliferation and promoted apoptosis in ST486 cells but also did so in a dose-dependent manner. Furthermore, the intracellular Ca2+ flux of ST486 cells was decreased after treatment with YSTB, inhibiting the excessive activation of ST486 cells, and these effects correlated with the CD19/FcγRIIb-Lyn-SHP-1 pathways. Our data showed that YSTB treatment inhibited the expression of phosphorylated CD19 and upregulated the protein expression of FcγRIIb, Lyn, and SHP-1. Additionally, the CIA model was established to explore the anti-inflammatory and inhibitory effects of YSTB on bone destruction, and we found that YSTB decreased the paw oedema and arthritis index (AI) in CIA rats. It is worth mentioning that YSTB clearly decreased the AI earlier than methotrexate (MTX) (day 10 vs 16). Moreover, synovial hyperplasia, inflammatory cell infiltration and cartilage surface erosion in CIA rats were noticeably reduced after treatment with YSTB as evidenced by histopathological examination. Finally, we found that YSTB treatment suppressed bone erosion and joint space score (JNS) in CIA rats as evidenced by radiographic assessment. In summary, these data suggest that YSTB has great therapeutic potential for RA treatment

Design and performance research of single rubber cylinder for high pressure gas injection packer

In order to solve the problem of "gas explosion" at the end of common rubber cylinder in the process of high temperature, high pressure and gas drive operation, the rubber cylinder with new structure suitable for 51/2 in casing pipe is developed. The "M" type single rubber cylinder structure is adopted in the new structure rubber cylinder, and the "gas explosion" problem of the end gas in the low-pressure side is solved by setting the double-layer staggered slotted steel cover to prevent outburst. The finite element method is used to simulate the setting of the rubber cylinder, and the structural parameters of the new rubber cylinder are obtained by single factor analysis and orthogonal optimization, simulation test and seal test were carried out to verify the sealing performance of the rubber cylinder. According to the actual working condition, the simulation test results and seal test results show that the sealing capacity of the packer reaches 50 MPa under the temperature resistance of 120℃, and the end steel cover is fully opened to wrap the rubber cylinder, which meets the operation requirements of high temperature and high pressure gas injection packer