Identify Urban Spatial Patterns Based on the Plot Shapes and Building Setting in Downtown of Nanjing

[EN] he geometric characteristics of modern cities have been difficult to describe that is important for urban design, which deserve to be further interpreted. Taking advantage of Conzen’s methodology, the building is tightly related with its plot, which means the certain building pattern can be described by examining the generation of the building arrangement within the plot. Simultaneously, the building pattern is highly affected by the plot pattern it is located. In view of these, plot patterns together with land property and site coding could be taken as the clue for understanding both building patterns and urban spatial configuration. 35 commercial blocks in Nanjing downtown areas are chosen as research samples. Firstly, the internal structure of the blocks will be studied by analyzing the patterns, functions and land utilities of its plots. Focusing on the site coding and regulation, the building arrangement could be clarified and mapped. The results will identify the urban spatial patterns in downtown of Nanjing by mapping the characteristics of plot size, shape, properties and boundary lines. Therefore, the method on describing urban spatial configuration in modern cities could be developed.This research is funded by National Natural Science Foundation of China (No. 51538005).Gu, Y.; Tang, L.; Ding, W. (2018). Identify Urban Spatial Patterns Based on the Plot Shapes and Building Setting in Downtown of Nanjing. En 24th ISUF International Conference. Book of Papers. Editorial Universitat Politècnica de València. 1431-1437. https://doi.org/10.4995/ISUF2017.2017.5924OCS1431143

Magic angles in twisted bilayer graphene near commensuration: Towards a hypermagic regime

The Bistritzer-MacDonald continuum model (BM model) describes the low-energy moir\'e bands for twisted bilayer graphene (TBG) at small twist angles. We derive a generalized continuum model for TBG near any commensurate twist angle, which is characterized by complex interlayer hoppings at commensurate $AA$ stackings (rather than the real hoppings in the BM model), a real interlayer hopping at commensurate $AB/BA$ stackings, and a global energy shift. The complex phases of the $AA$ stacking hoppings and the twist angle together define a single angle parameter $\phi_0$. We compute the model parameters for the first six distinct commensurate TBG configurations, among which the $38.2^\circ$ configuration may be within experimentally observable energy scales. We identify the first magic angle for any $\phi_0$ at a condition similar to that of the BM model. At this angle, the lowest two moir\'e bands at charge neutrality become flat except near the $\boldsymbol\Gamma_M$ point and retain fragile topology but lose particle-hole symmetry. We further identify a hypermagic parameter regime centered at $\phi_0 = \pm\pi/2$ where many moir\'e bands around charge neutrality (often $8$ or more) become flat simultaneously. Many of these flat bands resemble those in the kagome lattice and $p_x$, $p_y$ 2-orbital honeycomb lattice tight-binding models.Comment: 49 pages, 22 figures, accepted by Physical Review

An unambiguous test of positivity at lepton colliders

The diphoton channel at lepton colliders, $e^+e^- (\mu^+\mu^-) \to \gamma \gamma$, has a remarkable feature that the leading new physics contribution comes only from dimension-eight operators. This contribution is subject to a set of positivity bounds, derived from fundamental principles of Quantum Field Theory, such as unitarity, locality and analyticity. These positivity bounds are thus applicable to the most direct observable -- the diphoton cross sections. This unique feature provides a clear, robust, and unambiguous test of these principles. We estimate the capability of various future lepton colliders in probing the dimension-eight operators and testing the positivity bounds in this channel. We show that positivity bounds can lift certain degeneracies among the effective operators and significantly change the perspectives of a global analysis. We also perform a combined analysis of the $\gamma\gamma/Z\gamma/ZZ$ processes in the high energy limit and point out the important interplay among them.Comment: 6 pages, 4 figure

Nanoparticles and alloys for therapeutical and structural biomedical applications.

This thesis addresses 2 challenges in biomaterials research: 1) diffusion phenomena in Ti-Al-Nb alloys as materials for structural applications; and 2) the development of magnetic hyperthermia therapies against cancer more efficient and less invasive. Both challenges share a characteristic physical ground, which is the guideline of this work: they are based on transfer phenomena, mass transfer in the first case, and heat transfer in the second.Biomaterials research has been in an ascendant trend over the last decades. In biomedical applications, the first thing to be taken into consideration is biocompatibility. This property together with high specific strength, and good corrosion resistance has made titanium and its alloys the preferred materials for structural applications in the human body. Moreover, they have also been widely used in other fields like aerospace and marine industries. The composition of alloys is the most basic parameter that determines their properties. For instance, compared with the conventional Ti-6Al-4V alloy, some vanadium free titanium alloys like Ti-Al-Nb alloys, have higher fatigue strength, lower modulus of elasticity, and improved biocompatibility. All these properties are closely related to their microstructures that can be engineered by recovery, recrystallization, grain growth, transformation and precipitation. Furthermore, microstructural features can also be controlled to some extent by diffusion phenomena.Bibliometric studies show that in the uprising of Biomaterials research "Nanoparticles" has become the hottest topic after the turn of millennium. Indeed, nanotechnology, having been at the forefront of research for many years, has brought new genuine technical solutions in many different fields like biology, materials, electronics and medicine etc. One of the most exciting among them is that of therapeutical applications of nanoparticles (NPs), in which toxicity is also the main concern. For instance, in NP mediated magnetic hyperthermia for cancer therapy, only iron oxide nanoparticles (IONP), and particularly maghemite (-Fe2O3), are clinically accepted, in spite of existence of other materials like Co ferrite (CoFe2O4) that present clear advantages in terms of heating performance but show toxicity issues. Therefore, research efforts in this area have been mostly devoted to improve the performance of maghemite NPs by optimizing their structural parameters such as size, size distribution, shape, crystallinity, etc. There is however another polymorph of iron oxide, -Fe2O3, that has exceptional magnetic properties, but nevertheless has never been explored as a potential candidate for magnetic hyperthermia therapy.The idea of hyperthermia is to elevate the temperature of the tumor tissue over 42 ℃, in a selective way, to cause the apoptotic death of cancer cells. In order to heat selectively the tumor, it is peremptory to precisely monitor and control the temperature of the surrounding healthy tissue. Moreover, actual clinical magnetic hyperthermia technology uses massive direct injection of nanoparticles, which carries out some degree of invasiveness and toxicity issues. In order to avoid these problems and to expand the use of this technology in clinics, a new strategy has emerged that requires a reduced heat production. It is based on applying small amounts of heat but concentrated at certain intracellular regions that may lead to cancer cell apoptosis. To proof this hypothesis, it is first necessary to determine whether the heat produced by the MNPs is enough to generate large temperature gradients in small intracellular regions in the competition with heat dissipation process across the cell cytoplasm and then to the extracellular matrix. For this purpose, a non-invasive thermometric technique is required capable to determine local temperatures inside the cells with ultra-high spatial resolution. In this matter the use of lanthanide-based luminescent molecular thermometers can be a good option, as it will be shown in this thesis.This thesis is about: the diffusion phenomenon in the Ti-Al-Nb alloys, the hyperthermia performance of epsilon iron oxide nanoparticles, the fine-tuning of a ultra-high spatial and time resolution 2D temperature imaging system, the performance of Ln3+-bearing nanoparticles as nano-thermometry probes, obtaining intracellular temperature images, and the determination of temperature gradients in magnetic nanoparticles inside cancer cells under an ac magnetic field irradiation, and finally to investigate the validity of the local hyperthermia hypothesis.Chapter 1 will give a general introduction to the application of Titanium alloys and magnetic nanoparticles. The focus concerning titanium alloys will be put on diffusion phenomena, while in the case of magnetic nanoparticles, it will be mainly directed to magnetic hyperthermia and molecular nanothermometry.Chapter 2 contains the experimental section including methods, preparation and characterization of Titanium alloys, and magnetic and thermometric nanoparticle suspensions, and a description of the temperature imaging system.Chapter 3 is focused on diffusion phenomenon study of body centered cubic Ti-Al-Nb alloys by both experimental and computational methods, and the construction of a diffusion kinetic database. The experiments were conducted by the diffusion couple technique, and the computational work thereafter was accomplished by the DICTRA software.Chapter 4 and 5 demonstrates the hyperthermia performance of pure and Ga-doped epsilon iron oxide nanoparticles, in comparison with that of gamma iron oxide nanoparticles.Chapter 6 is dedicated to intracellular 2D temperature imaging and local magnetic hyperthermia by using Ln3+-bearing polymeric micelles.Chapter 7 is dedicated to the study of local hyperthermia by means of intracellular 2D temperature imaging of Ln3+-bearing iron oxide nanoparticles ac magnetic field application to cell cultures.<br /

Improved fracture toughness by microalloying of Fe in Ti-6Al-4V

The widely used Ti–6Al–4V (TC4) titanium alloy has been modified through the micro-alloying of Fe. The microstructural features and mechanical properties of the designed alloy, TC4F, are compared with other alloys in Ti–6Al–4V class by combining experimental characterizations and thermodynamic calculations. TC4F alloy not only maintains strength, hardness, and elongation similar to baseline TC4 but also exhibits improved fracture toughness comparable to TC4_ELI and even superior to TC4_DT under the heat-treated condition. It opens up a new cost-reducing way to enhance fracture toughness in place of controlling interstitial contents, showing potential in engineering applications. The discerned mechanisms indicate that the trace addition of Fe gives rise to composition redistribution between V and Fe in the ß phase, boosts the lattice distortion and vibration, thereafter enhances Young''s modulus and fracture toughness. It has been validated and verified by experiments, thermodynamic calculations, and Hahn-Rosenfield empirical research. The enhanced fracture toughness also benefits from the kinked ß+a lamellar microstructure at crack tip as well as the improved fracture surface due to the Fe addition. The enlarged plastic zone, redirected crack propagation, and more dimples with even-distributed size additionally contribute to the improvement of fracture toughness