Surveillance of Schistosoma japonicum Infection in Domestic Ruminants in the Dongting Lake Region, Hunan Province, China

Background: Schistosomiasis japonica is prevalent in Asian countries and it remains a major public health problem in China. The major endemic foci are the marsh and lake regions of southern China, particularly the Dongting Lake region bordering Hunan and Hubei provinces, and the Poyang Lake region in Jiangxi province. Domestic ruminants, especially bovines, have long been considered to play a major role in the transmission of Schistosoma japonicum to humans. Methods and Findings: A miracidial hatching technique was used to investigate the prevalence of S. japonicum infections in domestic ruminants and field feces collected from two towns located to the south and east of Dongting Lake, Hunan province, between 2005 and 2010. The overall prevalence of infection was not significantly reduced from 4.93 % in 2005 to 3.64 % in 2008, after which it was maintained at this level. Bovines comprised 23.5–58.2 % of the total infected ruminants, while goats comprised 41.8–76.5%. Infection rates in cattle and goats were significantly higher than those found in buffalo in most study years. The prevalence in buffalo younger than three years was significantly higher than that in those aged over three years. All the positive field samples of feces were derived from bovines in Nandashan. In Matang Town, 61.22 % of the positive field feces were from bovines, while the rest were from goats. The positive rates for field feces were approximately the same in April and November/October. Conclusions: The present study found that bovines and goats are major sources of S. japonicum infection in the Dongtin

Application and Optimization of Kalman Filter for Baseband Signal Processing of GPS Receivers

High sensitivity tracking in GPS receiver is required in many weak signal circumstances. The key of improving sensitivity is the optimization of the loop filter in tracking. As Kalman filter is the most optimized linear filter, it is used in many engineering fields. This article introduced the application of Kalman filter as the loop filter of the carrier tracking loop in GPS receiver, to improve tracking sensitivity. The traditional loop filter is replaced. Simulation results show that the new structure improves the tracking sensitivity by 6dB and can make the tracking loop more robust when the navigation signal is languishing. The optimization of theKalman filter is also analysed, which further improves the sensitivity by 4dB

Application and Optimization of Kalman Filter for Baseband Signal Processing of GPS Receivers

High sensitivity tracking in GPS receiver is required in many weak signal circumstances. The key of improving sensitivity is the optimization of the loop filter in tracking. As Kalman filter is the most optimized linear filter, it is used in many engineering fields. This article introduced the application of Kalman filter as the loop filter of the carrier tracking loop in GPS receiver, to improve tracking sensitivity. The traditional loop filter is replaced. Simulation results show that the new structure improves the tracking sensitivity by 6dB and can make the tracking loop more robust when the navigation signal is languishing. The optimization of theKalman filter is also analysed, which further improves the sensitivity by 4dB

Application and Optimization of Kalman Filter for Baseband Signal Processing of GPS Receivers

High sensitivity tracking in GPS receiver is required in many weak signal circumstances. The key of improving sensitivity is the optimization of the loop filter in tracking. As Kalman filter is the most optimized linear filter, it is used in many engineering fields. This article introduced the application of Kalman filter as the loop filter of the carrier tracking loop in GPS receiver, to improve tracking sensitivity. The traditional loop filter is replaced. Simulation results show that the new structure improves the tracking sensitivity by 6dB and can make the tracking loop more robust when the navigation signal is languishing. The optimization of theKalman filter is also analysed, which further improves the sensitivity by 4dB

Китайские регулирующие органы в системе сертификации CCC

The Chinese CCC Certification, also known as “China Compulsory Certification” (in Chinese: zhongguo guojia qiangzhixing chanpin renzheng, or just “3C”) is the most widespread product safety certification in China, it is a mandatory certification. It was implemented in the context of China’s admission to the World Trade Organization in 2002. The CCC-mark covers a broad range of products and applies not only to Chinese manufacturers but worldwide to all goods imported to China. The article provides an overview of the functions of the various bodies and institutions involved in the certification process

Gallic acid mitigates LPS-induced inflammatory response via suppressing NF-κB signalling pathway in IPEC-J2 cells.

peer reviewedGallic acid is a phenolic compound that exhibits antibacterial, antioxidative and anti-inflammatory functions. In a previous study, we found that dietary supplementation with gallic acid decreased incidence of diarrhoea and protected intestinal integrity in weaning piglets. However, the underlying mechanism remains unclear. Here, a pig intestinal epithelial cell line (IPEC-J2) was used as an in vitro model to explore the antioxidant and anti-inflammatory capacity of gallic acid. IPEC-J2 cells were stimulated with hydrogen peroxide (H2 O2 ) and lipopolysaccharide (LPS) to establish oxidative and inflammatory models, respectively. Results showed that H2 O2 significantly decreased catalase (CAT) secretion and CAT mRNA abundance in the cells (p < 0.05), while pretreatment with gallic acid did not prevent the decrease in CAT expression induced by H2 O2 . However, gallic acid pretreatment mitigated the increased expression of the tumour necrosis factor-α and interleukin-8 genes caused by LPS in IPEC-J2 cells (p < 0.05). In addition, pretreatment with gallic acid significantly suppressed phosphorylation of NF-κB and IκBα in LPS-stimulated IPEC-J2 cells. Moreover, LPS stimulation decreased the protein abundance of zona occludens 1 (ZO-1) and occludin, while pretreatment with gallic acid preserved expression level of tight junction proteins ZO-1 and occludin in LPS-stimulated IPEC-J2 cells (p < 0.05). In conclusion, gallic acid may mitigate LPS-induced inflammatory responses by inhibiting the NF-κB signalling pathway, exerting positive effects on the barrier function of IPEC-J2 cells

Effects of dietary fiber levels on cecal microbiota composition in geese

Objective This study shows the effects of dietary fiber levels on cecal microbiota composition in geese at day 70 according to pyrosequencing of the 16S ribosomal RNA gene. Methods A total of 468 1-day-old healthy male Yangzhou goslings with similar body weight were randomly divided into 3 groups with 6 replicates per group and 26 geese per replicate. Geese were fed diets with fiber levels of 2.5% (low fiber level diet, Group I) and 6.1% (Group III) during days 1–70, respectively, or 4.3% for days 1–28 and 6.1% for days 29–70 (Group II). Results Low fiber level diet decreased body weight, average daily gain during, increased lower feed conversation rate of geese during day 1 to 70 (p<0.05). Low fiber level diet decreased the total operational taxonomic units, Chao1 index and Shannon index, whereas increased the Simpson index of cecal microbiota in geese at day 70. Low fiber level diet decreased the relative abundance of Bacteroidetes, Firmicutes, Bacteroides, and Paraprevotella in cecum of geese at day 70. The similarity of cecal microbiota between low fiber level diet group and other groups was smaller. Conclusion This study indicates that the low fiber level diet decreased diversity of microbiota, and relative abundance of some beneficial microbiota in cecum of geese at day 70, implying that the low fiber level diet has negative influence on performance by altering the diversity and population of cecal microbiota in geese

The Effects of Dietary Silybin Supplementation on the Growth Performance and Regulation of Intestinal Oxidative Injury and Microflora Dysbiosis in Weaned Piglets

Oxidative stress is the major incentive for intestinal dysfunction in weaned piglets, which usually leads to growth retardation or even death. Silybin has caught extensive attention due to its antioxidant properties. Herein, we investigated the effect of dietary silybin supplementation on growth performance and determined its protective effect on paraquat (PQ)-induced intestinal oxidative damage and microflora dysbiosis in weaned piglets. In trial 1, a total of one hundred twenty healthy weaned piglets were randomly assigned into five treatments with six replicate pens per treatment and four piglets per pen, where they were fed basal diets supplemented with silybin at 0, 50, 100, 200, or 400 mg/kg for 42 days. In trial 2, a total of 24 piglets were randomly allocated to two dietary treatments with 12 replicates per treatment and 1 piglet per pen: a basal diet or adding 400 mg/kg silybin to a basal diet. One-half piglets in each treatment were given an intraperitoneal injection of paraquat (4 mg/kg of body weight) or sterile saline on day 18. All piglets were euthanized on day 21 for sample collection. The results showed that dietary supplementation with 400 mg/kg silybin resulted in a lower feed conversion ratio, diarrhea incidence, and greater antioxidant capacity in weaned piglets. Dietary silybin enhanced intestinal antioxidant capacity and mitochondrial function in oxidative stress piglets induced by PQ. Silybin inhibited mitochondria-associated endogenous apoptotic procedures and then improved the intestinal barrier function and morphology of PQ-challenged piglets. Moreover, silybin improved intestinal microbiota dysbiosis induced by the PQ challenge by enriching short-chain fatty-acid-producing bacteria, which augmented the production of acetate and propionate. Collectively, these findings indicated that dietary silybin supplementation linearly decreased feed conversion ratio and reduced diarrhea incidence in normal conditions, and effectively alleviated oxidative stress-induced mitochondrial dysfunction, intestinal damage, and microflora dysbiosis in weaned piglets

Study on the Ti/SnO 2/PbO 2 Anode in Sulphuric Acid Solution

由于硫酸溶液具有高的电导、一般条件下性质稳定、价格相对低廉等优点，所以电化学合成大多在硫酸溶液中进行．阳极析氧是电化学合成不可避免的阳极过程．但因硫酸的强腐蚀性，以及从阳极析出的氧的强氧化性，使得能满足工业生产的阳极材料很缺乏．自１９５０年荷兰Ｈｅｎ...The Ti/SnO 2/PbO 2 electrode, prepared by the electrodeposition method, was tested as the anode for the oxygen evolution reaction in 1 mol/L H 2SO 4 solution and examined by means of EDS, SEM and XRD. The electrocatalytic activity and the electrochemical stability of the prepared electrode were found to be superior.作者联系地址：太原理工大学材料工程学院材料系,太原理工大学化工系Author's Address: Dept of chem., Taiyuan univ.of tecnology,Taiyuan 03002