3,634 research outputs found

    Rheology at the micro-scale: new tools for bio-analysis

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    We present a simple and non-invasive experimental procedure to measure the linear viscoelastic properties of cells by passive particle tracking microrheology. In order to do this, a generalised Langevin equation is adopted to relate the timedependent thermal fluctuations of a probe sensor, immobilised to the cell’s membrane, to the frequency-dependent viscoelastic moduli of the cell. The method has been validated by measuring the linear viscoelastic response of a soft solid and then applied to cell physiology studies. It is shown that the viscoelastic moduli are related to the cell’s cytoskeletal structure, which in this work is modulated either by inhibiting the actin/myosin-II interactions by means of blebbistatin or by varying the solution osmolarity from iso- to hypo-osmotic conditions. The insights gained from this form of rheological analysis promises to be a valuable addition to physiological studies; e.g. cell physiology during pathology and pharmacological response

    FRW Universe in Ho\~rava Gravity

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    Recently, a field theoretic model for a UV complete theory of gravity has been proposed by Ho\~{r}ava. This theory is a non-relativistic renormalizable gravity theory which coincides with Einstein's general relativity at large distances. Subsequently L\"{u} et al have formulated the modified Friedmann equations and have presented a solution in vacuum. In the present work, we rewrite the modified FRW equations in the form of usual FRW equations in Einstein gravity and consequences has been analyzed. Also the thermodynamics of the FRW universe has been studied

    Numerical study of scars in a chaotic billiard

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    We study numerically the scaling properties of scars in stadium billiard. Using the semiclassical criterion, we have searched systematically the scars of the same type through a very wide range, from ground state to as high as the 1 millionth state. We have analyzed the integrated probability density along the periodic orbit. The numerical results confirm that the average intensity of certain types of scars is independent of \hbar rather than scales with \sqrt{\hbar}. Our findings confirm the theoretical predictions of Robnik (1989).Comment: 7 pages in Revtex 3.1, 5 PS figures available upon request. To appear in Phys. Rev. E, Vol. 55, No. 5, 199

    MIMO free-space optical communication employing subcarrier intensity modulation in atmospheric turbulence channels

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    In this paper, we analyse the error performance of transmitter/receiver array free-space optical (FSO) communication system employing binary phase shift keying (BPSK) subcarrier intensity modulation (SIM) in clear but turbulent atmospheric channel. Subcarrier modulation is employed to eliminate the need for adaptive threshold detector. Direct detection is employed at the receiver and each subcarrier is subsequently demodulated coherently. The effect of irradiance fading is mitigated with an array of lasers and photodetectors. The received signals are linearly combined using the optimal maximum ratio combining (MRC), the equal gain combining (EGC) and the selection combining (SelC). The bit error rate (BER) equations are derived considering additive white Gaussian noise and log normal intensity fluctuations. This work is part of the EU COST actions and EU projects

    Willmore minimizers with prescribed isoperimetric ratio

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    Motivated by a simple model for elastic cell membranes, we minimize the Willmore functional among two-dimensional spheres embedded in R^3 with prescribed isoperimetric ratio

    Comparison of Temperature-Dependent Hadronic Current Correlation Functions Calculated in Lattice Simulations of QCD and with a Chiral Lagrangian Model

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    The Euclidean-time hadronic current correlation functions, GP(τ,T)G_P(\tau, T) and GV(τ,T)G_V(\tau, T), of pseudoscalar and vector currents have recently been calculated in lattice simulations of QCD and have been used to obtain the corresponding spectral functions. We have used the Nambu-Jona-Lasinio (NJL) model to calculate such spectral functions, as well as the Euclidean-time correlators, and have made a comparison to the lattice results for the correlators. We find evidence for the type of temperature dependence of the NJL coupling parameters that we have used in previous studies of the mesonic confinement-deconfinement transition. We also see that the spectral functions obtained when using the maximum-entropy-method (MEM) and the lattice data differ from the spectral functions that we calculate in our chiral model. However, our results for the Euclidean-time correlators are in general agreement with the lattice results, with better agreement when our temperature-dependent coupling parameters are used than when temperature-independent parameters are used for the NJL model. We also discuss some additional evidence for the utility of temperature-dependent coupling parameters for the NJL model. For example, if the constituent quark mass at T=0 is 352MeV352 {MeV} in the chiral limit, the transition temperature is Tc=208MeVT_c=208 {MeV} for the NJL model with a standard momentum cutoff parameter. (If a Gaussian momentum cutoff is used, we find Tc=225MeVT_c=225 {MeV} in the chiral limit, with m=368MeVm=368 {MeV} at T=0.) The introduction of a weak temperature dependence for the coupling constant will move the value of TcT_c into the range 150-170 MeV, which is more in accord with what is found in lattice simulations of QCD with dynamical quarks

    Entropy and the variational principle for actions of sofic groups

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    Recently Lewis Bowen introduced a notion of entropy for measure-preserving actions of a countable sofic group on a standard probability space admitting a generating partition with finite entropy. By applying an operator algebra perspective we develop a more general approach to sofic entropy which produces both measure and topological dynamical invariants, and we establish the variational principle in this context. In the case of residually finite groups we use the variational principle to compute the topological entropy of principal algebraic actions whose defining group ring element is invertible in the full group C*-algebra.Comment: 44 pages; minor changes; to appear in Invent. Mat

    Finding co-solvers on Twitter, with a little help from Linked Data

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    In this paper we propose a method for suggesting potential collaborators for solving innovation challenges online, based on their competence, similarity of interests and social proximity with the user. We rely on Linked Data to derive a measure of semantic relatedness that we use to enrich both user profiles and innovation problems with additional relevant topics, thereby improving the performance of co-solver recommendation. We evaluate this approach against state of the art methods for query enrichment based on the distribution of topics in user profiles, and demonstrate its usefulness in recommending collaborators that are both complementary in competence and compatible with the user. Our experiments are grounded using data from the social networking service Twitter.com

    The asymptotic iteration method for the angular spheroidal eigenvalues with arbitrary complex size parameter c

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    The asymptotic iteration method is applied, to calculate the angular spheroidal eigenvalues λm(c)\lambda^{m}_{\ell}(c) with arbitrary complex size parameter cc. It is shown that, the obtained numerical results of λm(c)\lambda^{m}_{\ell}(c) are all in excellent agreement with the available published data over the full range of parameter values \ell, mm, and cc. Some representative values of λm(c)\lambda^{m}_{\ell}(c) for large real cc are also given.Comment: 15 pages, 1 figur

    Spin-dependent structure functions g^1\hat g_1 and g^2\hat g_2 for inclusive spin-half baryon production in electron-positron annihilation

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    Two spin-dependent structure functions g^1\hat g_1 and g^2\hat g_2 for the inclusive spin-half baryon production in electron-positron annihilation are studied in the context of QCD factorization as well as in the naive quark parton model. As a result, it is found that the sum of g^1\hat g_1 and g^2\hat g_2 is related to h^1\hat h_1 and g^T\hat g_T, two quark fragmentation functions defined by Jaffe and Ji. In connection with the measurement of quark fragmentation functions, the possible phenomenological consequences are discussed.Comment: RevTex, four Ps figures, to appear in Phys. Rev.
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