Genome-wide association analysis identifies resistance loci for bacterial blight in a diverse collection of indica rice germplasm

Bacterial blight, which is caused by Xanthomonas oryzae pv. oryzae (Xoo), is one of the most devastating rice diseases worldwide. The development and use of disease-resistant cultivars have been the most effective strategy to control bacterial blight. Identifying the genes mediating bacterial blight resistance is a prerequisite for breeding cultivars with broad-spectrum and durable resistance. We herein describe a genome-wide association study involving 172 diverse Oryza sativa ssp. indica accessions to identify loci influencing the resistance to representative strains of six Xoo races. Twelve resistance loci containing 121 significantly associated signals were identified using 317,894 single nucleotide polymorphisms, which explained 13.3–59.9% of the variability in lesion length caused by Xoo races P1, P6, and P9a. Two hotspot regions (L11 and L12) were located within or nearby two cloned R genes (xa25 and Xa26) and one fine-mapped R gene (Xa4). Our results confirmed the relatively high resolution of genome-wide association studies. Moreover, we detected novel significant associations on chromosomes 2, 3, and 6–10. Haplotype analyses of xa25, the Xa26 paralog (MRKc; LOC_Os11g47290), and a Xa4 candidate gene (LOC_11g46870) revealed differences in bacterial blight resistance among indica subgroups. These differences were responsible for the observed variations in lesion lengths resulting from infections by Xoo races P1 and P9a. Our findings may be relevant for future studies involving bacterial blight resistance gene cloning, and provide insights into the genetic basis for bacterial blight resistance in indica rice, which may be useful for knowledge-based crop improvement. (Résumé d'auteur

Search for C=+C=+ charmonium and XYZ states in e+e−→γ+He^+e^-\to \gamma+ H at BESIII

Within the framework of nonrelativistic quantum chromodynamics, we study the production of $C=+$ charmonium states $H$ in $e^+e^-\to \gamma~+~H$ at BESIII with $H=\eta_c(nS)$ (n=1, 2, 3, and 4), $\chi_{cJ}(nP)$ (n=1, 2, and 3), and $^1D_2(nD)$ (n=1 and 2). The radiative and relativistic corrections are calculated to next-to-leading order for $S$ and $P$ wave states. We then argue that the search for $C=+$ $XYZ$ states such as $X(3872)$, $X(3940)$, $X(4160)$, and $X(4350)$ in $e^+e^-\to \gamma~+~H$ at BESIII may help clarify the nature of these states. BESIII can search $XYZ$ states through two body process $e^+e^-\to \gamma H$, where $H$ decay to $J/\psi \pi^+\pi^-$, $J/\psi \phi$, or $D \bar D$. This result may be useful in identifying the nature of $C=+$ $XYZ$ states. For completeness, the production of $C=+$ charmonium in $e^+e^-\to \gamma +~H$ at B factories is also discussed.Comment: Comments and suggestions are welcome. References are update

N-[3-(Dimethyl­amino)­prop­yl]-N′-(2-hy­droxy-5-methyl­phen­yl)oxamide

In the title compound, C14H21N3O3, the oxamide group has a transoid conformation. In the crystal, the mol­ecules are connected by N—H⋯O and O—H⋯N hydrogen bonds into a double chain running along the b axis

Are gravitational wave ringdown echoes always equal-interval ?

Gravitational wave (GW) ringdown waveforms may contain "echoes" that encode new physics in the strong gravity regime. It is commonly assumed that the new physics gives rise to the GW echoes whose intervals are constant. We point out that this assumption is not always applicable. In particular, if the post-merger object is initially a wormhole, which slowly pinches off and eventually collapses into a black hole, the late-time ringdown waveform exhibit a series of echoes whose intervals are increasing with time. We also assess how this affects the ability of Advanced LIGO/Virgo to detect these new signals.Comment: 10 pages,5 figure