The Topological Structure of the Space-Time Disclination

The space-time disclination is studied by making use of the decomposition theory of gauge potential in terms of antisymmetric tensor field and $\phi$-mapping method. It is shown that the self-dual and anti-self-dual parts of the curvature compose the space-time disclinations which are classified in terms of topological invariants--winding number. The projection of space-time disclination density along an antisymmetric tensor field is quantized topologically and characterized by Brouwer degree and Hopf index.Comment: 18 pages, Revte

Topological aspect of black hole with Skyrme hair

Based on the $\phi$-mapping topological current theory, we show that the presence of the black hole leaves fractional baryon charge outside the horizon in the Einstein-Skyrme theory. A topological current is derived from the Einstein-Skyrme system, which corresponds to the monopoles around the black hole. The branch process (splitting, merging and intersection) is simply discussed during the evolution of the monopoles.Comment: 10 pages,0 figure

Nebulized PPARγ agonists: a novel approach to augment neonatal lung maturation and injury repair in rats.

BackgroundBy stimulating lipofibroblast maturation, parenterally administered peroxisome proliferator-activated receptor γ (PPARγ) agonists promote lung homeostasis and injury repair in the neonatal lung. In this study, we determined whether PPARγ agonists could be delivered effectively via nebulization to neonates, and whether this approach would also protect against hyperoxia-induced lung injury.MethodsOne-day old Sprague-Dawley rat pups were administered PPARγ agonists rosiglitazone (RGZ, 3 mg/kg), pioglitazone (PGZ, 3 mg/kg), or the diluent, via nebulization every 24 h; animals were exposed to 21% or 95% O2 for up to 72 h. Twenty-four and 72 h following initial nebulization, the pups were sacrificed for lung tissue and blood collection to determine markers of lung maturation, injury repair, and RGZ and PGZ plasma levels.ResultsNebulized RGZ and PGZ enhanced lung maturation in both males and females, as evidenced by the increased expression of markers of alveolar epithelial and mesenchymal maturation. This approach also protected against hyperoxia-induced lung injury, since hyperoxia-induced changes in bronchoalveolar lavage cell and protein contents and lung injury markers were all blocked by nebulized PGZ.ConclusionNebulized PPARγ agonist administration promotes lung maturation and prevents neonatal hyperoxia-induced lung injury in both males and females

Novel Topological Invariant in the U(1) Gauge Field Theory

Based on the decomposition of U(1) gauge potential theory and the $\phi$-mapping topological current theory, the three-dimensional knot invariant and a four-dimensional new topological invariant are discussed in the U(1) gauge field.Comment: 10 pages, 0 figures accepted by MPL

The association of HDL-apoCIII with coronary heart disease and the effect of statin treatment on it

Effect of statin treatment on lipid variables in CHD patients with DM or not. (DOC 37 kb