929 research outputs found

    Nonsense Surveillance in Lymphocytes?

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    Quantifying Discourse Support for Omitted Pronouns

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    Pro-drop is commonly seen in many languages, but its discourse motivations have not been well characterized. Inspired by the topic chain theory in Chinese, this study shows how character-verb usage continuity distinguishes dropped pronouns from overt references to story characters. We model the choice to drop vs. not drop as a function of character-verb continuity. The results show that omitted subjects have higher character history-current verb continuity salience than non-omitted subjects. This is consistent with the idea that discourse coherence with a particular topic, such as a story character, indeed facilitates the omission of pronouns in languages and contexts where they are optional.Comment: to be published in Proceedings of the Fifth Workshop on Computational Models of Reference, Anaphora and Coreference, 202

    Fibrinogen-Like Protein 2: Its Biological Function Across Cell Types and the Potential to Serve as an Immunotherapy Target for Brain Tumors

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    Brain tumors are among the 10 leading causes of cancer-related death and present unique treatment challenges due to their critical location, genetic heterogeneity, and the blood-brain barrier. Recent advances in targeted immunotherapy and immune checkpoint blocking therapy provide alternative therapeutic strategies for brain tumors. Fibrinogen-like protein 2 (FGL2), which induces transformation from low-grade glioma to high-grade glioblastoma, is a type II membrane protein that is highly expressed in both host immune cells and tumor cells. Studies have uncovered multiple forms of FGL2 proteins with a broad range of roles in inducing immune tolerance and avoiding immune surveillance in tumor cells. Of note, presence of FGL2 transforms low grade to high grade brain tumors via promoting Treg, macrophages, and perhaps stemness. Absence (knockout) of FGL2 in tumor cells (not in host cells) induces CD103 DC cells, which triggers tumor specific CD8 +T cell activity to reject brain tumor progression. Immunotherapies targeting FGL2 have shown great promise in improving survival time in murine models. In this article, we will summarize the biological function of FGL2 in immune and tumor cells

    Application analysis of ai technology combined with spiral CT scanning in early lung cancer screening

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    At present, the incidence and fatality rate of lung cancer in China rank first among all malignant tumors. Despite the continuous development and improvement of China's medical level, the overall 5-year survival rate of lung cancer patients is still lower than 20% and is staged. A number of studies have confirmed that early diagnosis and treatment of early stage lung cancer is of great significance to improve the prognosis of patients. In recent years, artificial intelligence technology has gradually begun to be applied in oncology. ai is used in cancer screening, clinical diagnosis, radiation therapy (image acquisition, at-risk organ segmentation, image calibration and delivery) and other aspects of rapid development. However, whether medical ai can be socialized depends on the public's attitude and acceptance to a certain extent. However, at present, there are few studies on the diagnosis of early lung cancer by AI technology combined with SCT scanning. In view of this, this study applied the combined method in early lung cancer screening, aiming to find a safe and efficient screening mode and provide a reference for clinical diagnosis and treatment.Comment: This article was accepted by Frontiers in Computing and Intelligent Systems https://drpress.org/ojs/index.php/fcis/article/view/15781. arXiv admin note: text overlap with arXiv:nlin/0508031 by other author
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