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Experimental observation of chiral phonons in monolayer WSe2
Chirality characterizes an object that is not identical to its mirror image. In condensed matter physics, Fermions have been demonstrated to obtain chirality through structural and time-reversal symmetry breaking. These systems display unconventional electronic transport phenomena such as the quantum Hall effect and Weyl semimetals. However, for bosonic collective excitations in atomic lattices, chirality was only theoretically predicted and has never been observed. We experimentally show that phonons can exhibit intrinsic chirality in monolayer tungsten diselenide, whose lattice breaks the inversion symmetry and enables inequivalent electronic K and -K valley states. The time-reversal symmetry is also broken when we selectively excite the valley polarized holes by circularly polarized light. Brillouin-zone-boundary phonons are then optically created by the indirect infrared absorption through the hole-phonon interactions. The unidirectional intervalley transfer of holes ensures that only the phonon modes in one valley are excited. We found that such photons are chiral through the transient infrared circular dichroism, which proves the valley phonons responsible to the indirect absorption has non-zero pseudo-angular momentum. From the spectrum we further deduce the energy transferred to the phonons that agrees with both the first principle calculation and the double-resonance Raman spectroscopy. The chiral phonons have significant implications for electron-phonon coupling in solids, lattice-driven topological states, and energy efficient information processing
Zero-Annotation Object Detection with Web Knowledge Transfer
Object detection is one of the major problems in computer vision, and has
been extensively studied. Most of the existing detection works rely on
labor-intensive supervision, such as ground truth bounding boxes of objects or
at least image-level annotations. On the contrary, we propose an object
detection method that does not require any form of human annotation on target
tasks, by exploiting freely available web images. In order to facilitate
effective knowledge transfer from web images, we introduce a multi-instance
multi-label domain adaption learning framework with two key innovations. First
of all, we propose an instance-level adversarial domain adaptation network with
attention on foreground objects to transfer the object appearances from web
domain to target domain. Second, to preserve the class-specific semantic
structure of transferred object features, we propose a simultaneous transfer
mechanism to transfer the supervision across domains through pseudo strong
label generation. With our end-to-end framework that simultaneously learns a
weakly supervised detector and transfers knowledge across domains, we achieved
significant improvements over baseline methods on the benchmark datasets.Comment: Accepted in ECCV 201
Detection of Bacteroides forsythus and Porphyromonas gingivalis from root canals
published_or_final_versio
Design of dual-band slotted patch hybrid couplers based on PSO algorithm
A planar 3 dB patch hybrid coupler using cross and circular-shape slots is presented for a dual-band application. By inductively loading a pair of cross slots and four circular holes on a square patch, the matching and isolation performance of the miniaturized patch hybrid coupler is improved. In addition, the open-circuited shunt stubs are further installed at four ports to realize two operating bands. Since the slotted patch resonator cannot be characterized by the closed-form transmission line theory, the particle swarm optimization (PSO) algorithm is constructed and integrated with a full-wave solver to determine the variable parameters of the proposed structure. Finally, a prototype dual-band coupler operating at 915 MHz and 1575 MHz is designed and fabricated. Measured results show a good agreement with those obtained from simulation. © 2011 VSP.postprin
Factors that influence quality and yield of circulating-free DNA: A systematic review of the methodology literature.
BACKGROUND: Circulating-free DNA (cfDNA) is under investigation as a liquid biopsy of cancer for early detection, monitoring disease progression and therapeutic response. This systematic review of the primary cfDNA literature aims to identify and evaluate factors that influence recovery of cfDNA, and to outline evidence-based recommendations for standardization of methods. METHODS: A search of the Ovid and Cochrane databases was undertaken in May 2018 to obtain relevant literature on cfDNA isolation and quantification. Retrieved titles and abstracts were reviewed by two authors. The factors evaluated include choice of specimen type (plasma or serum); time-to-processing of whole blood; blood specimen tube; centrifugation protocol (speed, time, temperature and number of spins); and methods of cfDNA isolation and quantification. FINDINGS: Of 4,172 articles identified through the database search, 52 proceeded to full-text review and 37 met the criteria for inclusion. A quantitative analysis was not possible, due to significant heterogeneity in methodological approaches between studies. Therefore, included data was tabulated and a textual qualitative synthesis approach was taken. INTERPRETATION: This is the first systematic review of methodological factors that influence recovery and quantification of cfDNA, enabling recommendations to be made that will support standardization of methodological approaches towards development of blood-based cancer tests
Solving multi-scale low frequency electromagnetic problems
In this paper, we will discuss two methods to tackle the low-frequency, multi-scale electromagnetics problem. First we will discuss the augmented electric field integral equation (AEFIE), and then, we will discuss the equivalence principle algorithm (EPA). The AEFIE allows the solution of such problems without the need to perform a loop search of a complex structure. The EPA allows the separation of circuit physics from wave physics in a multiscale problem. Hybridization of these two methods will be discussed.published_or_final_versionThe 4th European Conference on Antennas and Propagation (EuCAP) 2010, Barcelona, Spain, 12-16 April 2010. In Proceedings of the 4th EuCAP, 2010, p. 1-
Neural crest migration is driven by a few trailblazer cells with a unique molecular signature narrowly confined to the invasive front
Neural crest (NC) cell migration is crucial to the formation of peripheral tissues during vertebrate development. However, how NC cells respond to different microenvironments to maintain persistence of direction and cohesion in multicellular streams remains unclear. To address this, we profiled eight subregions of a typical cranial NC cell migratory stream. Hierarchical clustering showed significant differences in the expression profiles of the lead three subregions compared with newly emerged cells. Multiplexed imaging of mRNA expression using fluorescent hybridization chain reaction (HCR) quantitatively confirmed the expression profiles of lead cells. Computational modeling predicted that a small fraction of lead cells that detect directional information is optimal for successful stream migration. Single-cell profiling then revealed a unique molecular signature that is consistent and stable over time in a subset of lead cells within the most advanced portion of the migratory front, which we term trailblazers. Model simulations that forced a lead cell behavior in the trailing subpopulation predicted cell bunching near the migratory domain entrance. Misexpression of the trailblazer molecular signature by perturbation of two upstream transcription factors agreed with the in silico prediction and showed alterations to NC cell migration distance and stream shape. These data are the first to characterize the molecular diversity within an NC cell migratory stream and offer insights into how molecular patterns are transduced into cell behaviors
Event anisotropy in 4.2A GeV/c C+C collisions
The directed and elliptic flow of protons and negative pions in 4.2A GeV/c
C+C collisions is studied using the Fourier analysis of azimuthal
distributions. It is found that the protons exhibit pronounced directed flow,
while the flow of pions is either non existent or too weak to be detected
experimentally. Also, it is found that in the entire rapidity interval the
elliptic flow is very small if not zero. These results are confirmed by the
Quark-Gluon-String Model (QGSM) and the relativistic transport model (ART 1.0),
except that these models predict very weak antiflow of pions. The more detailed
comparison with the QGSM suggests that the decay of resonances and rescattering
of secondaries dominantly determine the proton and negative pion flow at this
energy.Comment: 7 pages, 3 figures, TeX file changed from double to single-spacin
Anisotropic flow in 4.2A GeV/c C+Ta collisions
Anisotropic flow of protons and negative pions in 4.2A GeV/c C+Ta collisions
is studied using the Fourier analysis of azimuthal distributions. The protons
exhibit pronounced directed flow. Directed flow of pions is positive in the
entire rapidity interval and indicates that the pions are preferentially
emitted in the reaction plane from the target to the projectile. The elliptic
flow of protons and negative pions is close to zero. Comparison with the
quark-gluon-string model (QGSM) and relativistic transport model (ART 1.0) show
that they both yield a flow signature similar to the experimental data.Comment: 4 pages, 3 figures, Accepted for publication in Phys. Rev.
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