536 research outputs found

    Evolution of cooperation in spatial traveler's dilemma game

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    Traveler's dilemma (TD) is one of social dilemmas which has been well studied in the economics community, but it is attracted little attention in the physics community. The TD game is a two-person game. Each player can select an integer value between RR and MM (R<MR < M) as a pure strategy. If both of them select the same value, the payoff to them will be that value. If the players select different values, say ii and jj (Ri<jMR \le i < j \le M), then the payoff to the player who chooses the small value will be i+Ri+R and the payoff to the other player will be iRi-R. We term the player who selects a large value as the cooperator, and the one who chooses a small value as the defector. The reason is that if both of them select large values, it will result in a large total payoff. The Nash equilibrium of the TD game is to choose the smallest value RR. However, in previous behavioral studies, players in TD game typically select values that are much larger than RR, and the average selected value exhibits an inverse relationship with RR. To explain such anomalous behavior, in this paper, we study the evolution of cooperation in spatial traveler's dilemma game where the players are located on a square lattice and each player plays TD games with his neighbors. Players in our model can adopt their neighbors' strategies following two standard models of spatial game dynamics. Monte-Carlo simulation is applied to our model, and the results show that the cooperation level of the system, which is proportional to the average value of the strategies, decreases with increasing RR until RR is greater than the threshold where cooperation vanishes. Our findings indicate that spatial reciprocity promotes the evolution of cooperation in TD game and the spatial TD game model can interpret the anomalous behavior observed in previous behavioral experiments

    The Extraction of Trajectories from Real Texts Based on Linear Classification

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    Proceedings of the 16th Nordic Conference of Computational Linguistics NODALIDA-2007. Editors: Joakim Nivre, Heiki-Jaan Kaalep, Kadri Muischnek and Mare Koit. University of Tartu, Tartu, 2007. ISBN 978-9985-4-0513-0 (online) ISBN 978-9985-4-0514-7 (CD-ROM) pp. 121-127

    Proteomic analysis of effluents from perfused human heart for transplantation: identification of potential biomarkers for ischemic heart damage

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    <p>Abstract</p> <p>Background</p> <p>Biomarkers released from the heart at early stage of ischemia are very important to diagnosis of ischemic heart disease and salvage myocytes from death. Known specific markers for blood tests including CK-MB, cardiac troponin T (cTnT) and cardiac troponin I (cTnI) are released after the onset of significant necrosis instead of early ischemia. Thus, they are not good biomarkers to diagnose myocardial injury before necrosis happens. Therefore, in this study, we performed proteomic analysis on effluents from perfused human hearts of donors at different ischemic time.</p> <p>Results</p> <p>After global ischemia for 0 min, 30 min and 60 min at 4°C, effluents from five perfused hearts were analyzed respectively, by High performance liquid chromatography-Chip-Mass spectrometry (HPLC-Chip-MS) system. Total 196 highly reliable proteins were identified. 107 proteins were identified at the beginning of ischemia, 174 and 175 proteins at ischemic 30 min and ischemic 60 min, respectively. With the exception of cardiac troponin I and T, all known biomarkers for myocardial ischemia were detected in our study. However, there were four glycolytic enzymes and two targets of matrix metalloproteinase released significantly from the heart when ischemic time was increasing. These proteins were L-lactate dehydrogenase B(LDHB), glyceraldehyde-3-phosphate dehydrogenase, glucose-6-phosphate isomerase (GPI), phosphoglycerate mutase 2 (PGAM2), gelsolin and isoform 8 of titin. PGAM2, LDHB and titin were measured with enzyme-linked immunosorbent assays kits. The mean concentrations of LDHB and PGAM2 in samples showed an increasing trend when ischemic time was extending. In addition, 33% identified proteins are involved in metabolism. Protein to protein interaction network analysis showed glycolytic enzymes, such as isoform alpha-enolase of alpha-enolase, isoform 1 of triosephosphate isomerase and glyceraldehyde-3-phosphate dehydrogenase, had more connections than other proteins in myocardial metabolism during ischemia.</p> <p>Conclusion</p> <p>It is the first time to use effluents of human perfused heart to study the proteins released during myocardial ischemia by HPLC-Chip-MS system. There might be many potential biomarkers for mild ischemic injury in myocardium, especially isoform 8 of titin and M-type of PGAM2 that are more specific in the cardiac tissue than in the others. Furthermore, glycolysis is one of the important conversions during early ischemia in myocardium. This finding may provide new insight into pathology and biology of myocardial ischemia, and potential diagnostic and therapeutic biomarkers.</p

    Bank lending and CEO turnover: Evidence from China

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    To maintain bank relationship, borrowers have motives to discipline themselves by forcing out underperforming CEOs. In this paper, we show that the state ownership in emerging markets renders this disciplinary mechanism ineffective. Using the contract information of bank loans for Chinese listed firms, we find that higher bank loan intensity overall does not affect the probability of forcing out an underperforming CEO. The absence of disciplinary effect is driven by the bank-firm pairs in which either the borrower or the lender is state-owned. However, the disciplinary effect is significant if a firm’s bank loans mostly consist of secured and short-term bank loans. Bank loans increase the likelihood of a forced CEO turnover, especially when joint-equity banks serve as the main lender. Overall, we propose that state ownership is an important factor driving the inefficiency of credit market in emerging countries

    Combining remote sensing and ground census data to develop new maps of the distribution of rice agriculture in China

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    Large-scale assessments of the potential for food production and its impact on biogeochemical cycling require the best possible information on the distribution of cropland. This information can come from ground-based agricultural census data sets and/or spaceborne remote sensing products, both with strengths and weaknesses. Official cropland statistics for China contain much information on the distribution of crop types, but are known to significantly underestimate total cropland areas and are generally at coarse spatial resolution. Remote sensing products can provide moderate to fine spatial resolution estimates of cropland location and extent, but supply little information on crop type or management. We combined county-scale agricultural census statistics on total cropland area and sown area of 17 major crops in 1990 with a fine-resolution land-cover map derived from 1995–1996 optical remote sensing (Landsat) data to generate 0.5° resolution maps of the distribution of rice agriculture in mainland China. Agricultural census data were used to determine the fraction of crop area in each 0.5° grid cell that was in single rice and each of 10 different multicrop paddy rice rotations (e.g., winter wheat/rice), while the remote sensing land-cover product was used to determine the spatial distribution and extent of total cropland in China. We estimate that there were 0.30 million km2 of paddy rice cropland; 75% of this paddy land was multicropped, and 56% had two rice plantings per year. Total sown area for paddy rice was 0.47 million km2. Paddy rice agriculture occurred on 23% of all cultivated land in China
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