FACTORS AFFECTING CONSUMER PREFERENCES FOR MAJOR FOOD MARKETS IN TAIWAN

The Food Industry Research and Development Institute conducted a nationwide survey of food consumption in Taiwan in 1999. A sample of 1200 consumers responded to a questionnaire, which asked whether there was a use/visit experience in the past year for each of six types of food markets: traditional vegetable market, supermarket, hypermarket, consumer cooperative, chain convenience store, and grocery store. Questions also asked which types of food markets consumers used most frequently for the purchase of fresh foods, planned purchases or occasional purchases of processed foods, and what factors influenced consumers to choose their most frequently used market. Nearly 84 percent of surveyed consumers have used/visited traditional vegetable markets in the past year, while 47 percent choose traditional markets as their most frequented marketplace for buying fresh food in Taiwan. Some 81 percent of surveyed consumers have used or visited a supermarket in past year, while 17.7 percent and 29.0 percent choose supermarkets as the most frequented marketplace for planned and occasional purchases of processed foods, respectively. We apply stepwise logistic regression to identify significant sociodemographic factors (such as gender, age, and others) which influence the choice of each of the six major types of food markets and to identify the promotional factors which positively or negatively influence consumers' preferences for the most often used market. Female consumers have almost four times higher odds of frequently using traditional vegetable markets in the past year. The unmarried, divorced/widowed, and/or those who had higher family monthly incomes demonstrate lower odds of frequently using traditional markets. For purchases of fresh foods, female respondents, older consumers, and/or those living in northern Taiwan have higher odds of choosing traditional vegetable markets as the most frequently used market, while occupation "chief," and those with higher levels of education have lower odds of choosing traditional markets. Price level influences consumers positively in choosing traditional vegetable markets, while products with mark registrations, such as GMP or CAS, negatively influence this choice. For planned purchases of processed foods, older consumers are more likely than others to choose traditional vegetable markets, and price level is also a positive influence for choosing these markets. For occasional purchases of processed foods, manual laborers and/or those living in northern Taiwan have higher odds of choosing traditional vegetable markets, while unmarried respondents have lower odds. Price level and products with nutrition labeling are positive promotional factors influencing consumers to choose traditional vegetable markets. For the other five market types, sociodemographic factors influence consumers' choices of markets differently in each case, but marketing factors also influence choices of which type of marketplace to use most frequently.Consumer/Household Economics,

Factors Affecting Consumer Preferences for Shrimp in Taiwan

Survey data of food consumption were analyzed utilizing stepwise logistic regression to investigate factors affecting consumer choice of shrimp as the most frequently consumed non-fish seafood in Taiwan. Demographic factors, consumer attention to food attributes, and consumer preferences for fish were considered in modeling. Results showed more people preferring shrimp than actually choosing shrimp. Those choosing shrimp as the most often consumed seafood tended to have higher personal income, lived in southern Taiwan, and/or chose shrimp as their favorite seafood, while those who chose shrimp less often were married and/or lived in Middle Taiwan. Those who chose shrimp as the favorite consumed seafood tended to be married, white collar workers, liked to eat fish, had higher personal income, lived in middle Taiwan, and/or chose shrimp as the most often consumed, while those who disfavored shrimp tended to be believers in the religions of Yi-Guan-Daoism or of Daoism

Post-Occupancy Evaluation of the Chicago Riverwalk

This study focused on evaluating how Sasaki has implemented the design goals for the Chicago Riverwalk mainly from social and ecological perspectives. The Chicago Riverwalk is composed of six blocks. In order to establish new connections to the river and enrich people’s life, each block was designed to provide diverse programs through changes in its shape and form. The Post-Occupancy Evaluation (POE) was conducted by mixed methods, including on-site survey, observation, expert interview and river sediment. The results indicate that goals in the theme of recreational and cultural were achieved very well. Goals in the theme of ecological may not be achieved as expected; however, people’s perception of ecological environment especially the aesthetics of the terrestrial and floating wetland vegetation design was good. Finally, shortcomings of the design relative to the design goals and recommendation for future post-occupancy evaluation project are discussed.Master of Landscape Architecture Master of ScienceSchool for Environment and SustainabilityUniversity of Michiganhttps://deepblue.lib.umich.edu/bitstream/2027.42/143161/1/Post-occupancy Evaluation of the Chicago Riverwalk_329.pd

Factors Affecting Consumer Choice of Canned Fish in Taiwan

Survey data on the choice of canned fish were analyzed through stepwise logistic regression. Those who lived in northern Taiwan, those who paid more attention to food taste, those who preferred to eat fish, those who liked to eat sour food, those who liked to eat bitter gourds, those employed in manual labor, and those who paid more attention to food content and ingredient had higher odds of eating canned fish, while those who believed in the religion of Yi-Guan-Daoism, those who paid greater attention to food nutrition, and females had lower odds of eating canned fish. To promote the development of canned fish, the taste and nutrition attributes of the products should be strengthened, especially in markets targeted at females

Factors Affecting Consumer Preferences for Fish in Taiwan

Stepwise logistic regression was used to explore consumption survey data to identify factors affecting consumer preference for fish in Taiwan. Most of the consumers responding prefer to eat fish, although the per capita consumption of fish was stagnant. Some demographic factors and consumer preference for food attributes were identified to affect preferences for fish. The older, white collar worker, those who believed in the religion of Daoism, those who paid more attention to food nutrition, to food taste, and/or to food quality had higher odds of preference for fish, while the unmarried, the female, those who believed in the religion of Yi-Guan-Daoism, those who lived in eastern, middle, or southern Taiwan had lower odds of preference for eating fish. The results implied that fish had an overall good perception in Taiwan. However, the fact that younger consumers and/or female consumers had lower odds in preference for fish implies a risk for future development. Further exploration of characteristics of food preference of these groups may be needed to illuminate information of marketing and product development for the fishery industry to further development.Keywords: consumer preferences, fish, food attributes, demographic factors, Taiwan, logistic regression

AluScan: a method for genome-wide scanning of sequence and structure variations in the human genome

<p>Abstract</p> <p>Background</p> <p>To complement next-generation sequencing technologies, there is a pressing need for efficient pre-sequencing capture methods with reduced costs and DNA requirement. The Alu family of short interspersed nucleotide elements is the most abundant type of transposable elements in the human genome and a recognized source of genome instability. With over one million Alu elements distributed throughout the genome, they are well positioned to facilitate genome-wide sequence amplification and capture of regions likely to harbor genetic variation hotspots of biological relevance.</p> <p>Results</p> <p>Here we report on the use of inter-Alu PCR with an enhanced range of amplicons in conjunction with next-generation sequencing to generate an Alu-anchored scan, or 'AluScan', of DNA sequences between Alu transposons, where Alu consensus sequence-based 'H-type' PCR primers that elongate outward from the head of an Alu element are combined with 'T-type' primers elongating from the poly-A containing tail to achieve huge amplicon range. To illustrate the method, glioma DNA was compared with white blood cell control DNA of the same patient by means of AluScan. The over 10 Mb sequences obtained, derived from more than 8,000 genes spread over all the chromosomes, revealed a highly reproducible capture of genomic sequences enriched in genic sequences and cancer candidate gene regions. Requiring only sub-micrograms of sample DNA, the power of AluScan as a discovery tool for genetic variations was demonstrated by the identification of 357 instances of loss of heterozygosity, 341 somatic indels, 274 somatic SNVs, and seven potential somatic SNV hotspots between control and glioma DNA.</p> <p>Conclusions</p> <p>AluScan, implemented with just a small number of H-type and T-type inter-Alu PCR primers, provides an effective capture of a diversity of genome-wide sequences for analysis. The method, by enabling an examination of gene-enriched regions containing exons, introns, and intergenic sequences with modest capture and sequencing costs, computation workload and DNA sample requirement is particularly well suited for accelerating the discovery of somatic mutations, as well as analysis of disease-predisposing germline polymorphisms, by making possible the comparative genome-wide scanning of DNA sequences from large human cohorts.</p

Lipid anti-lipid antibody responses correlate with disease activity in systemic lupus erythematosus.

Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder characterized by broad clinical manifestations including cardiovascular and renal complications with periodic disease flares and significant morbidity and mortality. One of the main contributing factors to the pathology of SLE is the accumulation and impaired clearance of immune complexes of which the principle components are host auto-antigens and antibodies. The contribution of host lipids to the formation of these autoimmune complexes remains poorly defined. The aim of the present study was to identify and analyze candidate lipid autoantigens and their corresponding anti-lipid antibody responses in a well-defined SLE patient cohort using a combination of immunological and biophysical techniques. Disease monitoring in the SLE cohort was undertaken with serial British Isles Lupus Assessment Group (BILAG) scoring. Correlations between specific lipid/anti-lipid responses were investigated as disease activity developed from active flares to quiescent during a follow up period. We report a significant negative correlation between anti-lipid antibodies for 24S-hydroxycholesterol, cardiolipin and phosphatidylserine with SLE disease activity. Taken together, these data suggest that lipid autoantigens represent a new family of biomarkers that can be employed to monitor disease activity plus the efficacy of therapeutic intervention in SLE

Sentinel lymph node biopsy as guidance for radical trachelectomy in young patients with early stage cervical cancer

<p>Abstract</p> <p>Background</p> <p>The purpose of this study was to assess the feasibility and accuracy of sentinel lymph nodes (SLNs) detection using 99mTc phytate in predicting pelvic lymph nodes status for radical abdominal trachelectomy (RAT) in patients with early stage cervical cancer.</p> <p>Methods</p> <p>Sixty-eight women with stage IA2-IB1 cervical cancer and scheduled to undergo fertility-sparing surgery enrolled in this study. 99mTc-labeled phytate was injected before surgery. Intraoperatively, SLNs were identified, excised, and submitted to fast frozen section. Systematic bilateral pelvic lymphadenectomy and/or para-aortic lymph node dissection was performed. Then RAT was performed in patients with negative SLNs. All nodes were sent for routine pathological examination and immunostained with anti-cytokeratin antibody to detect micrometastases. Outcomes of follow up and fertility were observed.</p> <p>Results</p> <p>SLNs were identified in 64 of 68 patients (94.1%). Of these, SLNs of 8 patients (11.8%) were positive on frozen sections and proved to be metastasis by final pathologic examination. The sensitivity, accuracy, and false negative rates were 100%, 100%, and 0%, respectively. All 60 patients with negative SLN underwent RAT successfully. Two relapses occurred and no one died of tumor progression during follow-up. Five of the 15 patients with procreative desire conceived 8 pregnancies (3 term delivery, 2 premature birth, 1 spontaneous abortion, and 2 were still in the duration of pregnancy) after surgery.</p> <p>Conclusions</p> <p>The identification of SLN using 99mTc-labeled phytate is accurate and safe to assess pelvic nodes status in patients with early cervical cancer. SLNs biopsy guided RAT is feasible for patients who desire to have fertility preservation.</p

Impact of the Herbal Medicine Sophora flavescens on the Oral Pharmacokinetics of Indinavir in Rats: The Involvement of CYP3A and P-Glycoprotein

Sophora flavescens is a Chinese medicinal herb used for the treatment of gastrointestinal hemorrhage, skin diseases, pyretic stranguria and viral hepatitis. In this study the herb-drug interactions between S. flavescens and indinavir, a protease inhibitor for HIV treatment, were evaluated in rats. Concomitant oral administration of Sophora extract (0.158 g/kg or 0.63 g/kg, p.o.) and indinavir (40 mg/kg, p.o.) in rats twice a day for 7 days resulted in a dose-dependent decrease of plasma indinavir concentrations, with 55%–83% decrease in AUC0-∞ and 38%–78% reduction in Cmax. The CL (Clearance)/F (fraction of dose available in the systemic circulation) increased up to 7.4-fold in Sophora-treated rats. Oxymatrine treatment (45 mg/kg, p.o.) also decreased indinavir concentrations, while the ethyl acetate fraction of Sophora extract had no effect. Urinary indinavir (24-h) was reduced, while the fraction of indinavir in faeces was increased after Sophora treatment. Compared to the controls, multiple dosing of Sophora extract elevated both mRNA and protein levels of P-gp in the small intestine and liver. In addition, Sophora treatment increased intestinal and hepatic mRNA expression of CYP3A1, but had less effect on CYP3A2 expression. Although protein levels of CYP3A1 and CYP3A2 were not altered by Sophora treatment, hepatic CYP3A activity increased in the Sophora-treated rats. All available data demonstrated that Sophora flavescens reduced plasma indinavir concentration after multiple concomitant doses, possibly through hepatic CYP3A activity and induction of intestinal and hepatic P-gp. The animal study would be useful for predicting potential interactions between natural products and oral pharmaceutics and understanding the mechanisms prior to human studies. Results in the current study suggest that patients using indinavir might be cautioned in the use of S. flavescens extract or Sophora-derived products