248 research outputs found

    Sleep duration and patterns in Chinese older adults: A comprehensive meta-analysis

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    This meta-analysis examined the mean sleep duration and patterns in Chinese older adult population. A literature search was systematically conducted covering major English (PubMed, Embase and PsycINFO) and Chinese (Chinese National Knowledge Infrastructure (CNKI), WanFang and SinoMed) databases. Data in studies with the mean and standard deviation of sleep duration and/or the proportion of short and long sleep durations in Chinese older adults were extracted and pooled using random-effects models. Subgroup analyses were conducted according to gender, region, area, survey time and sample size. A total of 36 studies with 150,616 subjects were included for analyses. The pooled mean sleep duration of 21 studies with available data was 6.82 hours/day (95% CI: 6.59–7.05 hours/day). The estimated proportions of sleep duration \u3c5 hours/day, \u3c6 hours/day, \u3c7 hours/day were 18.8% (95% CI: 1.7%–35.9%), 26.7% (95% CI: 19.7%–33.7%) and 42.3% (95% CI: 34.8%–49.8%), respectively. The pooled proportions for long sleepers were 22.6% (95% CI: 13.9%–31.4%) (\u3e8 hours/day) and 17.6% (95% CI: 12.4%–22.9%) (\u3e9 hours/day). Given the adverse effects of unhealthy sleep patterns, health professionals should pay more attention to sleep patterns in this population in China

    A new post-frac evaluation method for shale gas wells based on fracturing curves

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    AbstractPost-fracturing evaluation by using limited data is of great significance to continuous improvement of the fracturing programs. In this paper, a fracturing curve was divided into two stages (i.e., prepad fluid injection and main fracturing) so as to further understand the parameters of reservoirs and artificial fractures. The brittleness and plasticity of formations were qualitatively identified by use of the statistics of formation fracture frequency, and average pressure dropping range and rate during the prepad fluid injection. The composite brittleness index was quantitatively calculated by using the energy zones in the process of fracturing. It is shown from the large-scale true triaxial physical simulation results that the complexity of fractures is reflected by the pressure fluctuation frequency and amplitude in the main fracturing curve, and combined with the brittleness and plasticity of formations, the fracture morphology far away from the well can be diagnosed. Well P, a shale gas well in SE Chongqing, was taken as an example for post-fracturing evaluation. It is shown that the shale beds are of stronger heterogeneity along the extension directions of horizontal wells, and with GR 260 API as the dividing line between brittleness and plasticity in this area, complex fracture systems tend to form in brittleness-prone formations. In Well P, half of the fractures are single fractures, so it is necessary to carry out fine subsection and turnaround fracturing so as to improve development effects. This paper provides a theoretical basis for improving the fracturing well design and increasing the effective stimulated volume in this area

    Formation and properties of chalcogenide glasses based on GeS2-​Sb2S3-​AgI system

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    International audienceNovel glasses in GeS2-​Sb2S3-​AgI system have been prepd. by melt-​quenching method. A large glass-​forming region was found in this novel system, in which almost 60 mol​% AgI has been incorporated. The basic physiochem. properties of glass samples were investigated. With the addn. of AgI, red shift of short-​wavelength absorption edge and distinct drop of the glass transition temp. (Tg) were obsd. In addn., a high Ag+ ion cond. of 6.37×10-​4 S​/cm at room temp. was obtained in 55(0.6GeS2-​0.4Sb2S3)​-​45AgI sample, indicating that these glasses have potential application as amorphous solid electrolytes

    Digital village construction, human capital and the development of the rural older adult care service industry

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    BackgroundThe advancement of digital villages in China is shaped by the degree of human capital within the rural labor force, which not only restricts the potential of digital village but also influences the impact of digital empowerment on the progression of the rural older adult care service industry.Materials and methodsUsing panel data from 30 Chinese provinces between 2011 and 2020, we created benchmark and threshold regression models to investigate the influence of digital village construction on the development of the rural older adult care service industry and to delineate the threshold effects of human capital on it. We further scrutinized the correlation between the two systems, along with the factors that affect it, through a coupling coordination model.ResultsPreliminary, the baseline regression outcomes show that the digital village construction is conducive to the progression of the rural older adult care service industry (p < 0.05). Moreover, we identified a significant nonlinear threshold relationship between the digital village, human capital, and the advancement of the rural older adult care service industry (HUM1ST, p < 0.05; HUM2DT, p < 0.01; HUM3DT, p < 0.01). These results indicate that the digital technology’s effect on the development of the rural older adult care service industry is limited by the rural human capital level. Lastly, we found that higher levels of human capital enhance the coupling of the digital village with the rural older adult care service industry (p < 0.01), with the influence of per capita education level being the most pronounced (CoefHUM1 > CoefHUM2 > CoefHUM3).ConclusionThe digital village substantially empowers the rural older adult care service industry, with human capital exhibiting a significant threshold effect on this empowerment. Furthermore, variances in the level of human capital have a considerable impact on the integration of the digital village and the rural older adult care service industry

    The Establishment and Characteristics of Rat Model of Atherosclerosis Induced by Hyperuricemia

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    Epidemiological studies have identified hyperuricemia as an independent risk factor for cardiovascular disease. However, the mechanism whereby hyperuricemia causes atherosclerosis remains unclear. The objective of the study was to establish a new rat model of hyperuricemia-induced atherosclerosis. Wistar-Kyoto rats were randomly allocated to either a normal diet (ND), high-fat diet (HFD), or high-adenine diet (HAD), followed by sacrifice 4, 8, or 12 weeks later. Serum uric acid and lipid levels were analyzed, pathologic changes in the aorta were observed by hematoxylin and eosin staining, and mRNA expression was evaluated by quantitative real-time polymerase chain reaction. Serum uric acid and TC were significantly increased in the HAD group at 4 weeks compared with the ND group, but there was no significant difference in serum uric acid between the ND and HFD groups. Aorta calcification occurred earlier and was more severe in the HAD group, compared with the HFD group. Proliferating cell nuclear antigen, monocyte chemotactic factor-1, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 mRNA levels were increased in the HFD and HAD groups compared with the ND group. This new animal model will be a useful tool for investigating the mechanisms responsible for hyperuricemia-induced atherosclerosis
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