Étude des antineutrinos de réacteurs (mesure de l'angle de mélange leptonique et recherche d'éventuels neutrinos stériles)

L expérience Double Chooz a pour but la mesure précise de l angle de mélange . Son évaluation repose sur l étude de la disparition des antineutrinos produits par les réacteurs de la centrale de Chooz, disparition due au phénomène d oscillation des neutrinos. Deux détecteurs identiques composés de liquide scintillant permettent d effectuer une mesure relative, diminuant ainsi les incertitudes systématiques. Le détecteur proche, qui fournit la normalisation du flux de neutrinos émis, est en cours d installation, son achèvement est prévu pour le printemps 2014. Le détecteur lointain, sensible à l effet de , est situé à un kilomètre environ et prend des données depuis 2011. Dans cette première phase de l expérience, les données acquises par le détecteur lointain sont comparées à une prédiction du flux de neutrinos émis par les réacteurs pour estimer le paramètre . Au sein de cette thèse, l expérience Double Chooz et son analyse sont présentées. Une attention particulière est portée à l étude des bruits de fond et au rejet de signaux parasites constitués de flashs lumineux émis par les photo-multiplicateurs. Les flux de neutrons aux interfaces entre les différents volumes du détecteur affectent la définition du volume d interaction et partant l efficacité de détection. L étude détaillée de ces effets de bord est présentée. Dans le cadre de l expérience Double Chooz, des études ont été menées afin d améliorer la prédiction des flux de neutrinos émis par les réacteurs. Ces travaux ont mis à jour un déficit des taux de neutrinos observés dans les expériences passées à courtes distances des réacteurs. Ce déficit pourrait s expliquer par une oscillation vers une saveur stérile. Le projet Stereo a pour but d observer la distorsion caractéristique de l oscillation du spectre des neutrinos en énergie et en distance de propagation. Cette thèse s attache à présenter le concept du détecteur, les simulations réalisées, ainsi que les études de sensibilité. Les différents bruits de fond et les blindages envisagés pour s en prémunir sont enfin discutés.The Double Chooz experiment aims to measure the mixing angle through the disappearance induced by the oscillation phenomenon of anti-neutrinos produced by the Chooz nuclear reactors. In order to reduce systematic uncertainties, the experiment relies on the relative comparison of detected signals in two identical liquid scintillator detectors. The near one, giving the normalization of the emitted flux, is currently being built and will be delivered in spring 2014. The far detector, sensitive to , is located at about one kilometer and is taking data since 2011. In this first phase of the experiment, the far detector data are compared to a prediction of the emitted neutrino flux to estimate . In this thesis, the Double Chooz experiment and its analysis are presented, especially the background studies and the rejection of parasitic signals due to light emitted by photo-multipliers. Neutron fluxes between the different detector volumes impact the definition of the fiducial volume of neutrino interactions and the efficiency of detection. Detailed studies of these effects are presented. As part of the Double Chooz experiment, studies were performed to improve the prediction of neutrino flux emitted by reactors. This work revealed a deficit of observed neutrino rates in the short baseline experiments of last decades. This deficit could be explained by an oscillation to a sterile state. The Stereo project aims to observe a typical signature of oscillations: the distortion of neutrino spectra both in energy and baseline. This thesis presents the detector concept and simulations as well as sensitivity studies. Background sources and the foreseen shielding are also discussed.PARIS11-SCD-Bib. électronique (914719901) / SudocSudocFranceF

A proposed search for a fourth neutrino with a PBq antineutrino source

Several observed anomalies in neutrino oscillation data can be explained by a hypothetical fourth neutrino separated from the three standard neutrinos by a squared mass difference of a few eV^2. We show that this hypothesis can be tested with a PBq (ten kilocurie scale) 144Ce or 106Ru antineutrino beta-source deployed at the center of a large low background liquid scintillator detector. In particular, the compact size of such a source could yield an energy-dependent oscillating pattern in event spatial distribution that would unabiguously determine neutrino mass differences and mixing angles.Comment: 4 pages ; 1 table ; 4 figures - Add energy spectrum shape only analysis + referee comments/suggestion

A comprehensive revision of the summation method for the prediction of reactor antineutrino fluxes and spectra

The summation method for the calculation of reactor $\bar{\nu}_e$ fluxes and spectra is methodically revised and improved. For the first time, a complete uncertainty budget accounting for all known effects likely to impact these calculations is proposed. Uncertainties of a few percents at low energies and ranging up to 20% at high energies are obtained on the calculation of a typical reactor $\bar{\nu}_e$ spectrum. Although huge improvements have been achieved over the past decade, the quality and incompleteness of the present day evaluated nuclear decay data still limit the accuracy of the calculations and therefore dominate by far these uncertainties. Pushing the $\beta$-decay modeling of the thousands of branches making a reactor $\bar{\nu}_e$ spectrum to a high level of details comparatively brings modest changes. In particular, including nuclear structure calculations in the evaluation of the non-unique forbidden transitions gives a smaller impact than anticipated in past studies. Finally, this new modeling is challenged against state-of-the-art predictions and measurements. While a good agreement is observed with the most recent Inverse Beta Decay measurements of reactor $\bar{\nu}_e$ fluxes and spectra, it is unable to properly describe the reference aggregate $\beta$ spectra measured at the Institut Laue-Langevin High-Flux reactor in the 80s. This result adds to recent suspicions $\beta$ the reliability of these data and preferentially points toward a misprediction of the $^{235}$U $\bar{\nu}_e$ spectrum.Comment: 34 pages, 16 figures. Submitted to PR

Gravitational Waves From Known Pulsars: Results From The Initial Detector Era

We present the results of searches for gravitational waves from a large selection of pulsars using data from the most recent science runs (S6, VSR2 and VSR4) of the initial generation of interferometric gravitational wave detectors LIGO (Laser Interferometric Gravitational-wave Observatory) and Virgo. We do not see evidence for gravitational wave emission from any of the targeted sources but produce upper limits on the emission amplitude. We highlight the results from seven young pulsars with large spin-down luminosities. We reach within a factor of five of the canonical spin-down limit for all seven of these, whilst for the Crab and Vela pulsars we further surpass their spin-down limits. We present new or updated limits for 172 other pulsars (including both young and millisecond pulsars). Now that the detectors are undergoing major upgrades, and, for completeness, we bring together all of the most up-to-date results from all pulsars searched for during the operations of the first-generation LIGO, Virgo and GEO600 detectors. This gives a total of 195 pulsars including the most recent results described in this paper.United States National Science FoundationScience and Technology Facilities Council of the United KingdomMax-Planck-SocietyState of Niedersachsen/GermanyAustralian Research CouncilInternational Science Linkages program of the Commonwealth of AustraliaCouncil of Scientific and Industrial Research of IndiaIstituto Nazionale di Fisica Nucleare of ItalySpanish Ministerio de Economia y CompetitividadConselleria d'Economia Hisenda i Innovacio of the Govern de les Illes BalearsNetherlands Organisation for Scientific ResearchPolish Ministry of Science and Higher EducationFOCUS Programme of Foundation for Polish ScienceRoyal SocietyScottish Funding CouncilScottish Universities Physics AllianceNational Aeronautics and Space AdministrationOTKA of HungaryLyon Institute of Origins (LIO)National Research Foundation of KoreaIndustry CanadaProvince of Ontario through the Ministry of Economic Development and InnovationNational Science and Engineering Research Council CanadaCarnegie TrustLeverhulme TrustDavid and Lucile Packard FoundationResearch CorporationAlfred P. Sloan FoundationAstronom

Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs neutralizing type I IFNs

Life-threatening `breakthrough' cases of critical COVID-19 are attributed to poor or waning antibody response to the SARS- CoV-2 vaccine in individuals already at risk. Pre-existing autoantibodies (auto-Abs) neutralizing type I IFNs underlie at least 15% of critical COVID-19 pneumonia cases in unvaccinated individuals; however, their contribution to hypoxemic breakthrough cases in vaccinated people remains unknown. Here, we studied a cohort of 48 individuals ( age 20-86 years) who received 2 doses of an mRNA vaccine and developed a breakthrough infection with hypoxemic COVID-19 pneumonia 2 weeks to 4 months later. Antibody levels to the vaccine, neutralization of the virus, and auto- Abs to type I IFNs were measured in the plasma. Forty-two individuals had no known deficiency of B cell immunity and a normal antibody response to the vaccine. Among them, ten (24%) had auto-Abs neutralizing type I IFNs (aged 43-86 years). Eight of these ten patients had auto-Abs neutralizing both IFN-a2 and IFN-., while two neutralized IFN-omega only. No patient neutralized IFN-ss. Seven neutralized 10 ng/mL of type I IFNs, and three 100 pg/mL only. Seven patients neutralized SARS-CoV-2 D614G and the Delta variant (B.1.617.2) efficiently, while one patient neutralized Delta slightly less efficiently. Two of the three patients neutralizing only 100 pg/mL of type I IFNs neutralized both D61G and Delta less efficiently. Despite two mRNA vaccine inoculations and the presence of circulating antibodies capable of neutralizing SARS-CoV-2, auto-Abs neutralizing type I IFNs may underlie a significant proportion of hypoxemic COVID-19 pneumonia cases, highlighting the importance of this particularly vulnerable population