50,714 research outputs found

    A mechanical fastening technique development for application in space Final report

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    Mechanical fastening technique development for aerospace applicatio

    On Horizontal and Vertical Separation in Hierarchical Text Classification

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    Hierarchy is a common and effective way of organizing data and representing their relationships at different levels of abstraction. However, hierarchical data dependencies cause difficulties in the estimation of "separable" models that can distinguish between the entities in the hierarchy. Extracting separable models of hierarchical entities requires us to take their relative position into account and to consider the different types of dependencies in the hierarchy. In this paper, we present an investigation of the effect of separability in text-based entity classification and argue that in hierarchical classification, a separation property should be established between entities not only in the same layer, but also in different layers. Our main findings are the followings. First, we analyse the importance of separability on the data representation in the task of classification and based on that, we introduce a "Strong Separation Principle" for optimizing expected effectiveness of classifiers decision based on separation property. Second, we present Hierarchical Significant Words Language Models (HSWLM) which capture all, and only, the essential features of hierarchical entities according to their relative position in the hierarchy resulting in horizontally and vertically separable models. Third, we validate our claims on real-world data and demonstrate that how HSWLM improves the accuracy of classification and how it provides transferable models over time. Although discussions in this paper focus on the classification problem, the models are applicable to any information access tasks on data that has, or can be mapped to, a hierarchical structure.Comment: Full paper (10 pages) accepted for publication in proceedings of ACM SIGIR International Conference on the Theory of Information Retrieval (ICTIR'16

    Viking orbiter stereo imaging catalog

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    The extremely long mission of the two Viking Orbiter spacecraft produced a wealth of photos of surface features. Many of these photos can be used to form stereo images allowing the student of Mars to examine a subject in three dimensional. This catalog is a technical guide to the use of stereo coverage within the complex Viking imaging data set

    Longevity and mortality in Kennel Club registered dog breeds in the UK in 2014

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    Abstract Background The domestic dog is one of the most diverse mammalian species, exhibiting wide variations in morphology, behaviour and morbidity across breeds. Therefore, it is not unexpected that breeds should also exhibit variation in mortality and longevity. While shorter longevity per se may not necessarily be a welfare issue, a generally foreshortened lifespan in a breed that is accompanied by a high prevalence of a particular cause of death may reveal potentially serious welfare concerns and highlight scope to improve breed welfare. Survey data gathered directly from owners offer useful insights into canine longevity and mortality that can support the overall evidence base for welfare reforms within breeds. Results Mortality data on 5663 deceased dogs registered with the UK Kennel Club were collected from an owner-based survey. The most commonly reported causes of death were old age (13.8%), unspecified cancer (8.7%) and heart failure (4.9%); with 5.1% of deaths reported as unknown cause. Overall median age at death was 10.33 years (interquartile range: 7.17–12.83 years). Breeds varied widely in median longevity overall from the West Highland Terrier (12.71 years) to the Dobermann Pinscher (7.67 years). There was also wide variation in the prevalence of some common causes of death among breeds, and in median longevity across the causes of death. Conclusion Substantial variation in the median lifespan and the prominent causes of death exists across breeds. This study has identified some breeds with both a low median lifespan and also a high proportional mortality for one or more specific causes of death that should be considered as both potential welfare concerns as well as opportunities for improvement

    Large-scale survey to estimate the prevalence of disorders for 192 Kennel Club registered breeds

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    Abstract Background Pedigree or purebred dogs are often stated to have high prevalence of disorders which are commonly assumed to be a consequence of inbreeding and selection for exaggerated features. However, few studies empirically report and rank the prevalence of disorders across breeds although such data are of critical importance in the prioritisation of multiple health concerns, and to provide a baseline against which to explore changes over time. This paper reports an owner survey that gathered disorder information on Kennel Club registered pedigree dogs, regardless of whether these disorders received veterinary care. This study aimed to determine the prevalence of disorders among pedigree dogs overall and, where possible, determine any variation among breeds. Results This study included morbidity data on 43,005 live dogs registered with the Kennel Club. Just under two thirds of live dogs had no reported diseases/conditions. The most prevalent diseases/conditions overall were lipoma (4.3%; 95% confidence interval 4.13-4.52%), skin (cutaneous) cyst (3.1%; 2.94-3.27%) and hypersensitivity (allergic) skin disorder (2.7%; 2.52-2.82%). For the most common disorders in the most represented breeds, 90 significant differences between the within breed prevalence and the overall prevalence are reported. Conclusion The results from this study have added vital epidemiological data on disorders in UK dogs. It is anticipated that these results will contribute to the forthcoming Breed Health & Conservation Plans, a Kennel Club initiative aiming to assist in the identification and prioritisation of breeding selection objectives for health and provide advice to breeders/owners regarding steps that may be taken to minimise the risk of the disease/disorders. Future breed-specific studies are recommended to report more precise prevalence estimates within more breeds

    Critical X-ray Scattering Studies of Jahn-Teller Phase Transitions in TbV1x_{1-x}Asx_{x}O4_{4}

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    The critical behaviour associated with cooperative Jahn-Teller phase transitions in TbV1x_{1-x}Asx_{x}O4_{4} (where \textit{x} = 0, 0.17, 1) single crystals have been studied using high resolution x-ray scattering. These materials undergo continuous tetragonal \to orthorhombic structural phase transitions driven by Jahn-Teller physics at TC_C = 33.26(2) K, 30.32(2) K and 27.30(2) K for \textit{x} = 0, 0.17 and 1 respectively. The orthorhombic strain was measured close to the phase transition and is shown to display mean field behavior in all three samples. Pronounced fluctuation effects are manifest in the longitudinal width of the Bragg scattering, which diverges as a power law, with an exponent given by x=0.45±0.04x=0.45 \pm 0.04, on approaching the transition from either above or below. All samples exhibited twinning; however the disordered x = 0.17 sample showed a broad distribution of twins which were stable to relatively low temperatures, well below TC_C. This indicates that while the orthorhombic strain continues to develop in a conventional mean field manner in the presence of disorder, twin domains are easily pinned by the quenched impurities and their associated random strains.Comment: 8 pages, 6 figure

    Antigenic and genetic evolution of contemporary swine H1 influenza viruses in the United States

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    Several lineages of influenza A viruses (IAV) currently circulate in North American pigs. Genetic diversity is further increased by transmission of IAV between swine and humans and subsequent evolution. Here, we characterized the genetic and antigenic evolution of contemporary swine H1N1 and H1N2 viruses representing clusters H1-α (1A.1), H1-β (1A.2), H1pdm (1A.3.3.2), H1-γ (1A.3.3.3), H1-δ1 (1B.2.2), and H1-δ2 (1B.2.1) currently circulating in pigs in the United States. The δ1-viruses diversified into two new genetic clades, H1-δ1a (1B.2.2.1) and H1-δ1b (1B.2.2.2), which were also antigenically distinct from the earlier H1-δ1-viruses. Further characterization revealed that a few key amino acid changes were associated with antigenic divergence in these groups. The continued genetic and antigenic evolution of contemporary H1 viruses might lead to loss of vaccine cross-protection that could lead to significant economic impact to the swine industry, and represents a challenge to public health initiatives that attempt to minimize swine-to-human IAV transmission

    Cosmology on a Mesh

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    An adaptive multi grid approach to simulating the formation of structure from collisionless dark matter is described. MLAPM (Multi-Level Adaptive Particle Mesh) is one of the most efficient serial codes available on the cosmological 'market' today. As part of Swinburne University's role in the development of the Square Kilometer Array, we are implementing hydrodynamics, feedback, and radiative transfer within the MLAPM adaptive mesh, in order to simulate baryonic processes relevant to the interstellar and intergalactic media at high redshift. We will outline our progress to date in applying the existing MLAPM to a study of the decay of satellite galaxies within massive host potentials.Comment: 3 pages, 2 figures, to appear in the proceedings of "The IGM/Galaxy Connection - The Distribution of Baryons at z=0", ed. M. Putman & J. Rosenber

    Spatio-temporal patterns in a mechanical model for mesenchymal morphogenesis

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    We present an in-depth study of spatio-temporal patterns in a simplified version of a mechanical model for pattern formation in mesenchymal morphogenesis. We briefly motivate the derivation of the model and show how to choose realistic boundary conditions to make the system well-posed. We firstly consider one-dimensional patterns and carry out a nonlinear perturbation analysis for the case where the uniform steady state is linearly unstable to a single mode. In two-dimensions, we show that if the displacement field in the model is represented as a sum of orthogonal parts, then the model can be decomposed into two sub-models, only one of which is capable of generating pattern. We thus focus on this particular sub-model. We present a nonlinear analysis of spatio-temporal patterns exhibited by the sub-model on a square domain and discuss mode interaction. Our analysis shows that when a two-dimensional mode number admits two or more degenerate mode pairs, the solution of the full nonlinear system of partial differential equations is a mixed mode solution in which all the degenerate mode pairs are represented in a frequency locked oscillation

    Crystallization of the regulatory and effector domains of the key sporulation response regulator Spo0A

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    The key response-regulator gene of sporulation, spo0A, has been cloned from Bacillus stearothermophilus and the encoded protein purified. The DNA-binding and phospho-acceptor domains of Spo0A have been prepared by tryptic digestion of the intact protein and subsequently crystallized in forms suitable for X-ray crystallographic studies. The DNA-binding domain has been crystallized in two forms, one of which diffracts X-rays to beyond 2.5 Angstrom spacing. The crystals of the phospho-acceptor domain diffract X-rays beyond 2.0 Angstrom spacing using synchrotron radiation
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