Multimodal imaging for clinical target volume definition in prone whole-breast irradiation: a single institution experience

Aim: The aim was identification of reference structures for breast clinical target volume (CTV) in prone position, throughout image fusion process. Materials & methods: We analyzed breast glandular tissue distribution in 20 diagnostic MRIs, referring to structures reported in ESTRO guidelines for supine irradiation. The volume containing breast glandular tissue in all cases was defined as MRI prone CTV (MRIpCTV). Then in ten subsequent patients planned for prone irradiation, MRI and computed tomography (CT) simulation was acquired. MRIpCTV was defined followed by our findings and transferred to CT for definitive delineation. Results: MRIpCTV was defined by the caudal edge of clavicular head, 3 mm above inframammary fold, by the medial thoracic artery, by a plane passing through the lateral surface of pectoralis muscles, by the anterior surface of pectoralis muscles and 3 mm from the skin. Deformed CTV was consistent with anatomy on CT; the limits chosen for MRIpCTV fit adequately also for CT. Conclusion: Prone irradiation is an alternative set up for selected cases, so the sample is very small. However, our suggestions could be of aid in defining prone CTV. The good consistency between MRI and CT seems to confirm that MRI may be unnecessary in routine practice

18F-Fluorodeoxyglucose positron emission tomography for the assessment of myositis: a case series

To establish whether 18FFluorodeoxyglucose (FDG) positron emission computerised tomography (FDG-PET/CT) might reveal active disease in patients with myositis

Do dermatomyositis and polymyositis affect similar thigh muscles? A comparative MRI-based study

Dermatomyositis (DM) and polymyositis (PM) commonly cause weakness of the thigh muscles. However, it is debated whether DM and PM affect similar thigh muscles. Muscle oedema on fat-suppressed MRI sequences is thought to represent active inflammation. In this study, we aimed to assess which thigh muscle groups are preferentially inflamed in DM and PM, respectively, using short-tau inversion-recovery MRI sequences

Multimodal imaging for clinical target volume definition in prone whole-breast irradiation: a single institution experience

Aim: The aim was identification of reference structures for breast clinical target volume (CTV) in prone position, throughout image fusion process. Materials & methods: We analyzed breast glandular tissue distribution in 20 diagnostic MRIs, referring to structures reported in ESTRO guidelines for supine irradiation. The volume containing breast glandular tissue in all cases was defined as MRI prone CTV (MRIpCTV). Then in ten subsequent patients planned for prone irradiation, MRI and computed tomography (CT) simulation was acquired. MRIpCTV was defined followed by our findings and transferred to CT for definitive delineation. Results: MRIpCTV was defined by the caudal edge of clavicular head, 3 mm above inframammary fold, by the medial thoracic artery, by a plane passing through the lateral surface of pectoralis muscles, by the anterior surface of pectoralis muscles and 3 mm from the skin. Deformed CTV was consistent with anatomy on CT; the limits chosen for MRIpCTV fit adequately also for CT. Conclusion: Prone irradiation is an alternative set up for selected cases, so the sample is very small. However, our suggestions could be of aid in defining prone CTV. The good consistency between MRI and CT seems to confirm that MRI may be unnecessary in routine practice