Use of quantitative micro-complement fixation for detection of small differences in protein structure

Quantitative micro-complement fixation for detection of small differences in protein structur

Wave Mechanics of a Two Wire Atomic Beamsplitter

We consider the problem of an atomic beam propagating quantum mechanically through an atom beam splitter. Casting the problem in an adiabatic representation (in the spirit of the Born-Oppenheimer approximation in molecular physics) sheds light on explicit effects due to non-adiabatic passage of the atoms through the splitter region. We are thus able to probe the fully three dimensional structure of the beam splitter, gathering quantitative information about mode-mixing, splitting ratios,and reflection and transmission probabilities

Systematic winter sea-surface temperature biases in the northern Arabian Sea in HiGEM and the CMIP3 models

Analysis of 20th century simulations of the High resolution Global Environment Model (HiGEM) and the Third Coupled Model Intercomparison Project (CMIP3) models shows that most have a cold sea-surface temperature (SST) bias in the northern Arabian Sea during boreal winter. The association between Arabian Sea SST and the South Asian monsoon has been widely studied in observations and models, with winter cold biases known to be detrimental to rainfall simulation during the subsequent monsoon in coupled general circulation models (GCMs). However, the causes of these SST biases are not well understood. Indeed this is one of the first papers to address causes of the cold biases. The models show anomalously strong north-easterly winter monsoon winds and cold air temperatures in north-west India, Pakistan and beyond. This leads to the anomalous advection of cold, dry air over the Arabian Sea. The cold land region is also associated with an anomalously strong meridional surface temperature gradient during winter, contributing to the enhanced low-level convergence and excessive precipitation over the western equatorial Indian Ocean seen in many models

A Spitzer Spectrum of the Exoplanet HD 189733b

We report on the measurement of the 7.5-14.7 micron spectrum for the transiting extrasolar giant planet HD 189733b using the Infrared Spectrograph on the Spitzer Space Telescope. Though the observations comprise only 12 hours of telescope time, the continuum is well measured and has a flux ranging from 0.6 mJy to 1.8 mJy over the wavelength range, or 0.49 +/- 0.02% of the flux of the parent star. The variation in the measured fractional flux is very nearly flat over the entire wavelength range and shows no indication of significant absorption by water or methane, in contrast with the predictions of most atmospheric models. Models with strong day/night differences appear to be disfavored by the data, suggesting that heat redistribution to the night side of the planet is highly efficient.Comment: 12 pages, 3 figures, accepted for publication in the Astrophysical Journal Letter

Order in glassy systems

A directly measurable correlation length may be defined for systems having a two-step relaxation, based on the geometric properties of density profile that remains after averaging out the fast motion. We argue that the length diverges if and when the slow timescale diverges, whatever the microscopic mechanism at the origin of the slowing down. Measuring the length amounts to determining explicitly the complexity from the observed particle configurations. One may compute in the same way the Renyi complexities K_q, their relative behavior for different q characterizes the mechanism underlying the transition. In particular, the 'Random First Order' scenario predicts that in the glass phase K_q=0 for q>x, and K_q>0 for q<x, with x the Parisi parameter. The hypothesis of a nonequilibrium effective temperature may also be directly tested directly from configurations.Comment: Typos corrected, clarifications adde

Front Propagation up a Reaction Rate Gradient

We expand on a previous study of fronts in finite particle number reaction-diffusion systems in the presence of a reaction rate gradient in the direction of the front motion. We study the system via reaction-diffusion equations, using the expedient of a cutoff in the reaction rate below some critical density to capture the essential role of fl uctuations in the system. For large density, the velocity is large, which allows for an approximate analytic treatment. We derive an analytic approximation for the front velocity depe ndence on bulk particle density, showing that the velocity indeed diverge s in the infinite density limit. The form in which diffusion is impleme nted, namely nearest-neighbor hopping on a lattice, is seen to have an essential impact on the nature of the divergence

Making Deflection the New Diversion for Drug Offenders

The argument unfolds as follows. In Part I, we describe the origins and operation of deflection programs that currently exist in the United States and present the published empirical evidence about their effect on recidivism rates, as well as police and user population responses to them. We specifically discuss the LEAD template from Seattle, in addition to other models in Massachusetts and Texas. In Part II, we take a closer look at how conventional policing differs from the pre-arrest diversion program that was recently instituted in Atlanta. Using data from an original dataset of all 2012 felony drug arrests in Atlanta, we contrast the conventional approach to handling drug possession cases to the pre-arrest diversion approach and speculate about the savings that might have accrued had pre-arrest diversion been implemented years earlier. In Part III, we argue that prosecutors ought to become participants in and champions of county-wide deflection partnerships. As New Jersey\u27s Burlington County Prosecutor\u27s Office is the national leader in this effort, features of the Burlington program appear prominently in this discussion. We conclude on a comparative note, assessing how deflection measures up against conventional prosecution, diversion, and non-prosecution of substance users

Enhancement of the ν=5/2\nu = 5/2 Fractional Quantum Hall State in a Small In-Plane Magnetic Field

Using a 50-nm width, ultra-clean GaAs/AlGaAs quantum well, we have studied the Landau level filling factor $\nu = 5/2$ fractional quantum Hall effect in a perpendicular magnetic field $B \sim$ 1.7 T and determined its dependence on tilted magnetic fields. Contrary to all previous results, the 5/2 resistance minimum and the Hall plateau are found to strengthen continuously under an increasing tilt angle $0 < \theta < 25^\circ$ (corresponding to an in-plane magnetic field 0 $<$ $B_\parallel$ $< 0.8$ T). In the same range of $\theta$ the activation gaps of both the 7/3 and the 8/3 states are found to increase with tilt. The 5/2 state transforms into a compressible Fermi liquid upon tilt angle $\theta > 60^\circ$, and the composite fermion series [2+$p/(2p\pm1)$], $p =$ 1, 2 can be identified. Based on our results, we discuss the relevance of a Skyrmion spin texture at $\nu = 5/2$ associated with small Zeeman energy in wide quantum wells, as proposed by W$\acute{\text o}$js $et$ $al$., Phys. Rev. Lett. 104, 086801 (2010).Comment: 5+ pages, 3 figures, accepted for by Phy. Rev. Let