12 research outputs found

    Long Term Results Of A Phase Iii Multicentre Trial Of The Adjustable Male Sling For Treating Urinary Incontinence After Prostatectomy: Minimum 3 Years [resultados A Largo Plazo Del Estudio Multicéntrico Fase Iii Del Tratamiento De La Incontinencia De Orina Post Prostatectomia Con Un Sling Masculino Ajustable: Seguimiento Minimo 3 Años]

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    Objective: To communicate long- term results of the multicentre phase III trial post-prostatectomy urinary incontinence (PPI) treated with an adjustable male sling1. Patients and Methods: 48 PPI patients were included in this trial from april 2003 to September 2004. 39 post radical prostatectomy and 9 post adenomectomy. 19 wore 5 pads per day (3-8) each weight 83gr (17-198). 29 wore condom catheter or penile clamp The Argus was implanted through perineal approach. Using needles, the sling was transferred to the abdominal wall where it was adjusted by washers. The adjustment was done with retrograde urethral pressure from 45 to 55 cm water. Clinical data were updated till September 2007. The mean follow-up was 45 months (36-54) and median age was 67 years (52-77). The evaluation was: the ICIQ-SF score and qualification as Dry: no pads, Improved: 1 pad and Failed: 2 or more pads in 24 hr, including those with slings removed. Results: 47 were evaluated, resulting: 31 (66%) Dry, 6 (12.8%) Improved and 10 (21%) Failed. The ICIQ-SF score changed from 19.5 to 6. Of the 31 dry pts, 5 required one adjustment. 10 pts failed, 9 after sling removal, 6 due to erosion and 3 for infection. One patient failed with the sling in place, 6 erosions were registered: 4 in the urethra, 1 into the bladder and 1 through the abdominal wall. Perineal pain persisted in 2. One patient was excluded, died in September 2006. Conclusions: Argusâ„¢ has demonstrated its efficacy in long- term follow-up. The social continence rate was about 80%. The important comDlication was erosion or infection.333309314Romano, S.V., Metrebian, S.E., Vaz, F., Muller, V., Levi D'Ancona, C.A., Costa De Souza, E.A., Nakamura, F., An adjustable male sling for treating urinary Incontinence after prostatectomy - A phase 111 multi-centre trial (2006) BJU Int, 97 (3), pp. 533-539Shaeffer, A., Clemens, Q., Ferrari, M., Stamey, T., The male bulbourethral. Sling procedure for post-radical prostatectomy Incontinence (1998) J Urol, 159, pp. 510-1515Tse, V., Stone, A., Incontinence after prostatectomy: The artificial urlnay sphincter (2003) BJU Int, 92 (9), pp. 886-889Urban, M., Heracek, J., Romano, S.V., New sugical method of trea-tement for male Incontinence with argus adjustable male sling (2006) Urologe Pro Praxl, 1, pp. 20-23Galllstl, H., Shlarp, O., Hiibner, W.A., Argus: Elne neuartlge adjus-tlerbare shllnge In der theraple der postprostatektomlelncontl-nenz (2006) Urologe A, 45 (SUPPL. 1), pp. S43Sandoval, J.C., Salazar, A., Oyanedel, P., Verdugo, F., Romano, S.V., Sling bulbouretral para el tratamiento de la Incontlnencla urinaria de esfuerzo mascullna post cirugia prostatlca (2007) Rev. Chllena De Urologla., 72 (2), pp. 185-188Reges, R., Dancona, C., Rels, L., Mlyakoa, R., Netto, N., Treatmet of Male Urinary Incontinence with Male Sling: Long Term Follow-up Ics 2006, , Abst 361Kaufman, J.J., A New operation for male Incontinence (1970) Surg Gynecol Obstet., 131 (2), pp. 295-299Kaufman, J.J., Surgical treatment of post-prostatectomy Incontinence: Use of the penile crura to compress the bulbous urethra (1972) J Urol, 107 (2), pp. 293-297Kaufman, J.J., Treatment of post-prostatectomy urinary Incontinence using a silicone gel prosthesis (1973) Br J Urol., 45 (6), pp. 646-653Comlter, C.V., Sullivan, M.P., Yalla, S.V., Retrograde leak point pressure for evaluating post-radical prostatectomy Incontinence (1997) Urology., 49 (2), pp. 231-236Stamey, T., Perineal compression of the corpum spongiosum of the bulbar urethra. An operation for post-radical prostatectomy incontinence (1994) J Urol(Part 2), 151 (PART. 2). , 490A, Abstract 1049Romano, S.V., Tecnica quinirgica del sling masculino (2005) Rev. Arg. De Urol., 70 (3)Sousa-Escandon, A., Rodriguez Gomez, J.I., Uribarri Gonzalez, C., Marquez-Queimadelos, A., Externally readjustable sling on male stress urinary incontinence treatment: Point of technique and preliminary results (2004) J Endourol., 18 (1), pp. 113-11

    Correlates of sexual functioning in Italian menopausal women.

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    Abstract OBJECTIVES: To analyze the sexuality of Italian menopausal women. DESIGN: Cross-sectional study. POPULATION: Menopausal women consecutively observed during the study period in menopause clinics. METHODS: Women were interviewed about their current and premenopausal sexual activity: sexual intercourse frequency and self-rated sexual desire, capacity for orgasm and sexual satisfaction were recorded. Women were defined as having poor sexual functioning if they had one or less sexual intercourses per week or answered 'absent/poor' to the questions about the sexual domains. RESULTS: Oral hormone therapy (HT) use (odds ratio (OR) 0.43 for desire, 0.54 for orgasm and 0.56 for overall sexual satisfaction, all p < 0.001) and transdermal HT (OR 0.38, 0.53 and 0.53, respectively, all p < 0.001) were significantly associated with lower risk of poor sexual functioning. Higher physical and mental component scores (PCS and MCS, range 0-100) of the Short Form-12 are inversely related to poor sexual functioning (OR by point 0.96, 0.95, 0.95 for PCS and 0.96, 0.96 and 0.95, for MCS, respectively, all p < 0.001). Pain during and symptoms after sexual intercourse were significantly related to desire (OR 1.96 and 1.78, respectively), orgasm (OR 2.22 and 2.06, respectively) and sexual satisfaction (OR 2.02 and 1.79, respectively). The partner's health problems were associated with low sexual intercourse frequency (OR 4.18, p < 0.001) and absent/poor overall satisfaction (OR 2.61, p < 0.001). CONCLUSIONS: This study shows that, in menopausal Italian women attending menopause clinics, sexual function is associated with the quality of sexual life in reproductive age, partner's health status, current quality of life, HT and occurrence of pain during and symptoms after sexual intercour

    Risk factors for type 2 diabetes in women attending menopause clinics in Italy: a cross-sectional study

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    OBJECTIVE: To analyze risk factors for type 2 diabetes among women attending menopause clinics in Italy for counselling about the menopause. SUBJECTS: Women attending a network of first-level outpatient menopause clinics in Italy for general counselling about menopause or treatment of menopausal symptoms. METHODS: Cross-sectional study with no exclusion criteria. Type 2 diabetes was defined according to National Diabetes Data Groups Indications and the fasting blood glucose at an oral glucose tolerance test within the previous year. RESULTS: Out of the 44 694 considered in this analysis, 808 had a diagnosis of diabetes type 2 (1.8%). In comparison with women aged or = 57 years. Type 2 diabetes was less frequently reported in more educated women (OR high school/university vs. primary school = 0.44 (95% CI, 0.36-0.55)). Being overweight was associated with an increased risk of type 2 diabetes. In comparison with women reporting a low level of physical activity, the multivariate OR of type 2 diabetes was 0.67 (95% CI, 0.54-0.84) for women reporting regular physical activity. In comparison with premenopausal women, the multivariate OR of type 2 diabetes was 1.38 (95% CI, 1.03-1.84) in women with natural menopause. This finding was present also after allowing for the potential confounding effect of age. The multivariate OR of diabetes for users of hormonal replacement therapy was 0.58 (95% CI, 0.46-0.73). CONCLUSIONS: This large cross-sectional study suggests that postmenopausal women are at higher risk of type 2 diabetes after allowance for the effect of age. Other main determinants of risk of type 2 diabetes in women around menopause were low socioeconomic status and being overweight. Diabetes was found less frequently in those taking hormone replacement therapy

    FACTORS ASSOCIATED WITH CLIMATERIC SYMPTOMS IN WOMEN AROUND MENOPAUSE ATTENDING MANOPAUSE CLINICS IN ITALY

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    Objective: To obtain data on correlates of climacteric symptoms in women around menopause attending menopause clinics in Italy. Methods: Since 1997 a large cross sectional study has been conducted on the characteristics of women around menopause attending a network of first level menopause outpatient\u2019s clinics in Italy. A total of 66,501 (mean age 54.4 years) women are considered in the present paper. Results: The odds ratios of moderate and severe hot flashes/night sweats were lower in more educated women and (for severe symptoms only) in women reporting regular physical activity. Depression, difficulty to sleep, forgetfulness and irritability tended to be less frequent in more educated women and (depression only) in women reporting regular physical activity. Parous women reported more frequently these symptoms. Conclusions: This large study confirms in Southern European population that low education, body mass index and low physical activity are associated with climacteric symptoms. Parous women are at greater risk of psychological symptoms. \ua9 2005 Elsevier Ireland Ltd. All rights reserved
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